Climate changes are increasing over time, adversely affecting water availability and crop productivity. Potassium silicate (K-Si) or Triacontanol (TRIA) reportedly plays an important role in mitigating water stress conditions. A two-year field experiment was carried out during the 2021 and 2022 growing seasons to assess the effect of three irrigation treatments as 120, 100 and 80% of reference evapotranspiration (ETo) and foliar spraying with K-Si and TRIA, compared to control (no spraying) on the yield, water and land equivalent ratio as well as farmer's benefits of sesame intercropped with peanut system (33% S: 100% P). The average values of applied irrigation water were 9654, 8045 and 6436 m 3 /ha for irrigation with 120, 100 and 80% ETo, respectively. The results indicated that the highest yield of both crops was obtained under irrigation with 120% ETo and spraying with K-Si. Foliar spraying with K-Si or TRIA mitigates the adverse effects of low irrigation water application and its adverse effects on yield and its components in both crops under study. Irrigation with 100% ETo (saved 17% of the applied water under 120% ETo) and spraying with K-Si produced a higher yield of both crops than the obtained under irrigation with 120% ETo and no spraying. Furthermore, the highest value of water equivalent ratio (WER), land equivalent ratio (LER), total income (TI) and monetary advantage index (MAI) of sesame intercropped with peanut system were found under irrigation with 120% ETo and spraying with K-Si. However, irrigation with 100% ETo and spraying with K-Si produced higher values of these indices than the obtained under irrigation with 120% ETo and no spraying. Thus, it could be concluded that, to increase the productivity of unit land and water (LER and WER), as well as TI and MAI of sesame intercropped with peanut, irrigation with 120% ETo and spraying with K-Si should be utilized. Furthermore, to save 17% of the applied irrigation water, irrigation with 100% ETo and spraying with K-Si can be used and that obtained higher values of LER, WER, TI and MAI, than the obtained under irrigation with 120% ETo and no spraying.