Impact of mitral transcatheter edge-to-edge repair on pulmonary vein flow in patients with functional mitral regurgitation

Abstract

Mitral transcatheter edge-to-edge mitral valve repair (M-TEER) with the MitraClip system (Abbott Vascular, Santa Clara, California, USA) represents an option for selected patients with functional mitral regurgitation (FMR), 1-4 having also been associated in some cases with improved left ventricular (LV) strain and volumes. 5 Intra-procedural evaluation of the hemodynamic effect of M-TEER in this setting is still a matter for debate. Previous studies suggested intra-procedural assessment of pulmonary vein (PV) flow to estimate modifications in LV filling pressure and left atrial (LA) pressure. [6][7][8] The aim of our study was to evaluate the intra-procedural changes of PV flow after MitraClip positioning in patients affected by heart failure with reduced ejection fraction (HFrEF) and FMR.