Oil leak from vehicles is one of the most common pollution types of the road. The spilled oil could be retained on the surface and spread in the air voids of the road, which results in a decrease in the friction coefficient of the road, affects driving safety, and causes damage to pavement materials over time. Photocatalytic degradation through nano-TiO2 is a safe, long-lasting, and sustainable technology among the many methods for treating oil contamination on road surfaces. In this study, the nano-TiO2 photocatalytic degradation effect of road surface oil pollution was evaluated through the lab experiment. First, a glass dish was used as a substrate to determine the basic working condition of the test; then, a test method considering the impact of different oil erosion degrees was proposed to eliminate the effect of oil erosion on asphalt pavement and leakage on cement pavement, which led to the development of a lab test method for the nano-TiO2 photocatalytic degradation effect of oil pollution on different road surfaces.