Impact of neuropathy on the adherence to diabetes-related self-care activities: a cross-sectional study

Timar, Bogdan; Timar, Romulus; Schiller, Adalbert; Oancea, Cristian; Roman, Deiana; Vlad, Mihaela; Balinisteanu, Bogdan; Mazilu, Octavian

doi:10.2147/ppa.s107621

Cited by 12 publications

(16 citation statements)

References 23 publications

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“…The most frequent variant of defeat of peripheral nervous system at a diabetes is distal symmetric sensorimotor neuropathy [21]. As a rule, this complication occurs in a few years from the onset of the underlying disease [22]. This form of diabetic polyneuropathy develops slowly (chronically), the first symptoms (numbness and paresthesia) occur in the lower extremities, sometimes unilateral [23].…”

Section: Introductionmentioning

confidence: 99%

Dynamic Properties of Skeletal Muscle Contraction in Rats with Diabetes

Beregova¹,

Nozdrenko²,

SergiiBerehovyi³

et al. 2018

Pathophysiology - Altered Physiological States

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The study was conducted on 20 white nonlinear male rats, which were divided into 2 groups of 10 animals each. Rats in the first group were used as control. Rats in the second group were induced type I diabetes by intraperitoneal (i.p.) administration of streptozotocin (65 mg/kg). Diabetes in rats was confirmed by the presence of hyperglycemia. For the establishment of nociceptive pain sensation, mechanical nociceptive test and tail-flick test were conducted in rats. Further animals were anesthetized by i.p. administration of Nembutal (40 mg/kg). The study of dynamic properties of muscle contraction was performed under conditions of the tibia muscle activation by using the modulated stimulation of efferent n. tibialis. Streptozotocin (STZ) was injected in rats; as a result, the blood glucose level was increased by 4.4 times (p ≤ 0.001). Pain sensitivity in diabetic rats was suppressed, indicating the development of peripheral neuropathy. In rats with diabetes, biomechanical parameters of tibia muscle contraction such as the maximum force of contraction, the speed of maximum force of contraction, the retention time of maximum force of contraction and integrated power of muscle contraction (it is calculated on the total area of the received force curves) were violated. This prevents adequate implementation motor neuron pools muscular system, which will have significant consequences in accurate positional movements.

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Section: Introductionmentioning

confidence: 99%

Dynamic Properties of Skeletal Muscle Contraction in Rats with Diabetes

Beregova¹,

Nozdrenko²,

SergiiBerehovyi³

et al. 2018

Pathophysiology - Altered Physiological States

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“…The use of exercise counselling and goal setting with follow‐up phone calls may be an effective way of providing some level of supervision, which is important in building participants' self‐regulation, especially when attempting to maintain compliance for a long‐term training programme . The individually tailored exercise counselling approach might also enhance self‐management skills and facilitate building exercise habits into lifestyle, as DPN is associated with a lower level of self‐care in areas including exercise and diet management …”

Section: Discussionmentioning

confidence: 99%

“…35 The individually tailored exercise counselling approach might also enhance self-management skills and facilitate building exercise habits into lifestyle, as DPN is associated with a lower level of self-care in areas including exercise and diet management. 36 DPN is thought to be caused by the cellular damage and inflammatory cascade induced by chronic hyperglycaemia and dyslipidaemia, [37][38][39][40][41] which arise from insulin resistance. However, many people with established T2DM develop DPN despite adequate glucose control, 3 and current evidence does not prove the effectiveness of intensive glycaemic control on DPN progression in T2DM.…”

Section: Adverse Eventsmentioning

confidence: 99%

Aerobic exercise training may improve nerve function in type 2 diabetes and pre‐diabetes: A systematic review

Dennis

Kiernan

et al. 2018

Diabetes Metabolism Res

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Summary Diabetic neuropathy is a major complication of type 2 diabetes. Emerging evidence also suggests that people with pre‐diabetes may develop similar symptoms related to nerve dysfunction. While regular exercise provides many benefits to patients with diabetes, whether exercise influences nerve function has not been established. As such, the aim of this systematic review was to evaluate current evidence regarding the effect of exercise training on the progression and development of diabetic neuropathy. A systematic search of MEDLINE (Ovid), CINAHL, AMED, PEDro, the Cochrane Library, Embase, and Scopus databases identified a total of 12 studies that were eligible for inclusion in this systematic review. Quality rating and data extraction were performed by two independent reviewers. The 12 included studies examined people with pre‐diabetes (n = 1) and with type 2 diabetes (n = 11). There was heterogeneity of study quality and exercise type and dosage among these studies. Eleven studies reported that exercise training had a positive influence on nerve function or neuropathy‐related symptoms; and only one study reported mild adverse events. Evidence from this systematic review suggests aerobic exercise training may positively influence nerve function among people with type 2 diabetes, with minimal risk of adverse events. Further research will be required to determine the optimal dosage of exercise training and the effect on nerve function in pre‐diabetes and in women with previous gestational diabetes. This review is registered on PROSPERO (CRD42018088182).

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“…There is increasing evidence to suggest that the peripheral impact of neuropathy extends beyond physical symptomology. People presenting with neuropathy are often identi ed as having lower selfesteem, an increase in depression symptomology, and as being less inclined to exercise and maintain a healthy diet [12,13]. A cyclical situation ensues with depression leading to poorer self-care behaviours, which in turn leads to worsening neuropathy and increasingly severe depression [12].…”

Section: Introductionmentioning

confidence: 99%

“…People presenting with neuropathy are often identi ed as having lower selfesteem, an increase in depression symptomology, and as being less inclined to exercise and maintain a healthy diet [12,13]. A cyclical situation ensues with depression leading to poorer self-care behaviours, which in turn leads to worsening neuropathy and increasingly severe depression [12]. An additional layer of complexity exists in that healthcare professionals tend to be insu ciently equipped to assist with the emotional and psychological components of self-management education [14].…”

Section: Introductionmentioning

confidence: 99%

Do standard neurological assessments tell us more than we realise?

Donnan¹,

Baker²,

Horn³

et al. 2020

Preprint

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Background Neurological assessments are commonly performed by podiatrists as a screening tool for peripheral neuropathy, and to identify the risk of foot ulceration and amputation. Monofilament and tuning fork assessments are routinely used to assess peripheral sensation. Whilst these assessments are commonly used to monitor foot health, there is potential for neurological results to illuminate a broader and more holistic perspective of a person’s overall health status. Methods Recruitment of fifty participants (31 female, 19 male; 71.78±9.64 years) for foot health screening was associated with a foot health week promotional event at the Charles Sturt University Community Engagement and Wellness Centre. Under the guidance of registered podiatrists, fourth year podiatry students completed basic neurological assessments to determine each participant’s neurological status. Participants also completed a modified Foot Health Status Questionnaire (FHSQ). Age and monofilament results were analysed using Spearman’s rho, while correlations involving FHSQ data were identified using a Kruskal-Wallis test. Results For those participants who reported an excellent rating of their own health, there was a statistically significant relationship with adequate vibration sensation (p<0.01). A person’s ability to get up from a sitting position (p<0.01), lift and carry shopping (p=0.02) and climb a flight of stairs (p=0.03), was significantly correlated with more sites detected using monofilament assessment. Discussion Significant correlations were observed between basic neurological assessments and a number of activities of daily living. While the findings reflect a correlational relationship, not causational, this still provides an opportunity for clinicians to view neurological assessment results more holistically. Whilst the immediate focus for a practitioner will be tissue viability, neurological findings may be useful to stimulate further discussion about a patient’s functional capacity by exploring issues beyond the presenting condition.

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Impact of neuropathy on the adherence to diabetes-related self-care activities: a cross-sectional study

Cited by 12 publications

References 23 publications

Dynamic Properties of Skeletal Muscle Contraction in Rats with Diabetes

Dynamic Properties of Skeletal Muscle Contraction in Rats with Diabetes

Aerobic exercise training may improve nerve function in type 2 diabetes and pre‐diabetes: A systematic review

Do standard neurological assessments tell us more than we realise?

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