Impact of Ozone gel, PRF &amp; A-PRF on Pain and Trismus during Tissue Healing after Extraction of Mandibular Third Molars

Yousef, Eman; Ateia, Islam; Mansour, Noha O.; Abdelsameaa, Sally

doi:10.21608/edj.2021.76920.1643

Cited by 4 publications

(2 citation statements)

References 35 publications

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“…and study groups. While Alkholy et al,51 reported no statisti-cally significant difference in trismus between the study and control groups, Yousef et al,52 and Sivalingam Ozone as a supportive therapy may be use-ful in lowering pain, but it was ineffective in the reduction of trismus and swelling, according to the findings of the current study.It is impossible to provide a practical suggestion for employing ozone as a supportive therapy to reduce trismus, pain, and swelling in lower third molar extractions due to the limits of this research and the extremely low certainty of the studies' findings. To increase the certainty of the evidence, more standardized protocols must be established for this therapy.…”

supporting

confidence: 53%

Efficiency of topical ozone gel as an adjunct to antibiotics and analgesics on sequelae after extraction of impacted mandibular third molar

Alhelu,

Mahdi,

Saadi Abdulhameed

2023

J Oral Res

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Introduction: Extraction of the impacted mandibular third molar is a common procedure in dentistry. Many complications may arise after this operation, the most common being pain, trismus, and swelling. Systemic medications have been used in an attempt to manage these problems, but because of their side effects, the need for non-medication treatment arises to treat these complications without side effects, such as cryotherapy, ice packs, low-level laser therapy, and ozone. Ozone is one of the most effective antimicrobials used in the dentistry field, and it also has a positive effect on soft tissue healing, activates cellular metabolism, and can react with blood components; for these reasons ozone is used to manage trismus, swelling, and pain after removal of the mandibular third molar. Aim: The purpose of the study was to assess the effects of topical ozone gel on complications from the extraction of the impacted mandibular third molar. Materials and Methods: Thirty patients were enrolled in the current study and were randomly divided into two equal groups. Preoperatively clinical examination included measurement of facial swelling measurements and maximum mouth opening. The position and configuration of the impacted lower third molar, the surrounding bone, the mandibular canal, and the neighboring tooth were all assessed using a panoramic X-ray. On days 2 and 7, after surgery, the facial swelling dimensions and maximum mouth opening were again assessed. Statistics were used to analyze results. Results: Findings indicate statistical significance for pain, but not for swelling or mouth opening. Conclusions: After lower third molar surgery, topical ozone gel helps reduce postoperative pain. Keywords: Molar, third; Tooth, impacted; Ozone; Pain; Trismus; Edema.

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supporting

confidence: 53%

Efficiency of topical ozone gel as an adjunct to antibiotics and analgesics on sequelae after extraction of impacted mandibular third molar

Alhelu,

Mahdi,

Saadi Abdulhameed

2023

J Oral Res

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“…Articles dealing with the management of pediatric and nonsurgical cancer patients (cancer surgery) with CPSP were excluded from this evidence-based guideline. The severity of pain was assessed with the visual analog scale 45 , brief pain inventory 46 , and leeds assessment of neuropathic signs and symptoms 47 (Annex 2, Supplemental Digital Content 1, http://links.lww.com/MS9/A227 ).…”

Section: Resultsmentioning

confidence: 99%

Evidence-based guideline on chronic postsurgical pain management in adult patients in resource-restricted setting, 2023: systematic review and guideline

Milkias,

Mekonnen,

Ahmed

et al. 2023

Annals of Medicine &Amp; Surgery

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Background: Chronic postsurgical pain (CPSP) after tissue trauma is frequent and may have a long-lasting impact on the functioning and quality of life. The development of CPSP increases the burden on both the patient and the community. This review aims to systematically review articles and, lastly, pull an evidence-based guideline for CPSP management in adult patients in resource-limited areas. Methodology: The review was reported based on preferred reporting items for the systemic review and meta-analysis (PRISMA) protocol. A literature search was conducted from the Cochrane, PubMed/Medline, and Google Scholar databases, and other gray literature from 2010 to 2022. The conclusion was made based on the level of evidence. Results: A total of 3521 articles were identified through the database by searching strategies. Finally, by filtering duplicates unrelated to the topics, 22 articles (9 meta-analyses and systematic reviews, 12 systematic reviews, and one cohort study) were selected on the management of CPSP in adult patients. Filtering was made based on the intervention, outcome data of the population, and methodological quality. Conclusion: Given the complexity and multidimensional nature of chronic postsurgical pain, effective assessment, and management require a comprehensive, multiaxial approach. Adequate preoperative preparation and counseling, potential risk identification and optimization, and use of a multimodal approach, and noninvasive surgical techniques are crucial in reducing the development of chronic postsurgical pain.

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Evaluation of ozonated olive gel in treatment of chronic osteomyelitis of the jaws in diabetic patients

Saleh,

Khedr,

Saad

et al. 2023

Tanta Dental Journal

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Purpose This study was planned to evaluate clinically and radiographically the use of ozonated olive gel in the treatment of chronic osteomyelitis of the jaws in diabetic patients. Patients and methods This prospective study that was carried out on twenty controlled diabetic patients with osteomyelitis of the jaws and were divided randomly into two equal groups. Group 1 (study group): included 10 patients were treated by surgical debridement and systemic antimicrobial therapy with topical application of ozonated olive gel. Group II (control group): comprised of 10 patients were treated by surgical debridement and systemic antimicrobial therapy only. All Patients underwent regular follow-ups clinically and radiographically for six months. Results Clinically, there was a significant decrease in postoperative pain and enhancement of wound healing in the study group. There was no significant difference in edema between both groups. Radiographically, by CBCT there was a significant increase in bone height gain and bone density in the study group at P value <0.05. Conclusion This study showed significant effect of ozone gel on pain, soft tissue healing and elimination of infection as well as significant increase in bone height gain and bone density.

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Impact of Ozone gel, PRF & A-PRF on Pain and Trismus during Tissue Healing after Extraction of Mandibular Third Molars

Cited by 4 publications

References 35 publications

Efficiency of topical ozone gel as an adjunct to antibiotics and analgesics on sequelae after extraction of impacted mandibular third molar

Efficiency of topical ozone gel as an adjunct to antibiotics and analgesics on sequelae after extraction of impacted mandibular third molar

Evidence-based guideline on chronic postsurgical pain management in adult patients in resource-restricted setting, 2023: systematic review and guideline

Evaluation of ozonated olive gel in treatment of chronic osteomyelitis of the jaws in diabetic patients

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