“…(11) In the United States, the annual incidence of aortic valve replacement surgery is 8.33 per 100,000 Medicare beneficiaries under 65 years. (12) In the same work, the total annual incidence of aortic valve interventions was 88.9 per 100,000 Medicare beneficiaries (including transcatheter aortic valve implantation (TAVI) and elderly patients). ( 12) Compared with these values, we can say that patients with BAV have a much higher incidence of valve replacement than the general population.…”