Impact of parametric imaging on contrast-enhanced ultrasound of breast cancer

Abstract

The use of parametric imaging improves the visibility of CEUS. The maximal diameter of the tumor determined on CEUS correlates substantially with the pathology.

Quantification of dynamic contrast-enhanced ultrasound (CEUS) in non-cystic breast lesions using external perfusion software

“… Author, Journal, Year, Title No. of lesions Conclusion Accuracy, sensitivity, specificity Du YR et al, Clinical Hemorheol Microcirculation, 2018 Application of contrast-enhanced ultrasound in the diagnosis of small breast lesions 19 105 CEUS was useful to differentiate benign from malignant breast lesions Acc: 80.9 Sens: 78.7 Spec: 84.1 Noro A et al, J Med Ultrasonics 2016 Impact of parametric imaging on contrast-enhanced ultrasound of breast cancer 20 65 The use of parametric imaging improves visibility of breast cancer NA Xiao X et al, PLoS One 2014 Breast contrast-enhanced ultrasound: is a scoring system feasible 21 839 The contrast-enhancement patterns of benign and malignant breast lesions is different Acc: 90.8 Sens: 93.7 Spec: 88.7 Luo J et al, World J Radiol 2016 Contrast-enhanced ultrasound improves performance of breast imaging reporting and data system of critical breast lesions 22 235 The evaluation of BI-RADS 4 lesions with CEUS result in reduced biopsy rates and increased cancer-to-biopsy yields Sens: 85.4 Spec: 87.8 Luo J et al, World J Radiol 2016 Predictive model for contrast-enhanced ultrasound of the breast 23 235 The breast CEUS model can predict risk of malignant breast lesions more accurately Sens: 84.4 Spec: 82.7 Sarocco A et al, Acta radiologica 2012 Differentiation between benign and malignant breast tumor using kinetic features of real-time harmonic contrast-enhanced ultrasound 24 96 Real-time CEUS can evolve into a new non-invasive option for differentiation of malignant from benign breast lesions NA Zhao H et al, European Journal of Radiology 2008 Contrast-enhanced ultrasound is helpful in the differentiation of malignant and benign breast lesions 25 76 CEUS cooperation with conventional US shows improved accuracy in ...…”

Diagnostic Value of Arrival Time Parametric Imaging Using Contrast‐Enhanced Ultrasonography in Superficial Enlarged Lymph Nodes

“…They concluded that, compared with routine CEUS, micro‐flow imaging could more effectively display specific features and could offer improved diagnostic performance in the differentiation of atypical HCC from FNH, especially when used by resident radiologists. Noro et al prospectively evaluated the usefulness of CEUS using parametric imaging for breast cancer in a multicenter study and found that the use of parametric imaging improved the visibility of CEUS. Most of the reports used an ultrasound system by the Toshiba Medical Systems Corporation (now Canon Medical Systems Corporation), and the contrast agent used was Sonazoid.…”

“…There were some differences in the perception of contrast enhancement on parametric color maps and conventional CEUS mode. Noro et al found that CEUS for breast examination was subjective; it was sometimes difficult to obtain agreement among operators. Yuan et al reported that parametric images enabled the objective distinction of malignant and benign breast tumors, clarifying the degree of homogeneity or heterogeneity within the tumor.…”

“…In arrival‐time parametric imaging, a color map overlying the B‐mode image is created for the region of interest, and different colors in this map are coded according to the arrival time of the microbubbles. Recently, several articles reported the value of arrival‐time parametric imaging in the diagnosis of focal liver lesions, breast cancers, adrenal nodules, and even diffuse liver disease . Until now, there has been no report focused on the use of arrival‐time parametric imaging technique on the diagnosis of superficial lymphadenopathy.…”

“…Recently, several articles reported the value of arrival-time parametric imaging in the diagnosis of focal liver lesions, breast cancers, adrenal nodules, and even diffuse liver disease. [10][11][12][13] Until now, there has been no report focused on the use of arrival-time parametric imaging technique on the diagnosis of superficial lymphadenopathy.…”