Impact of patient‐reported outcome measures on routine practice: a structured review

Marshall, Susan; Haywood, Kirstie L.; Fitzpatrick, Ray

doi:10.1111/j.1365-2753.2006.00650.x

Cited by 546 publications

(428 citation statements)

References 54 publications

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“…The importance of incorporating patients' perspectives in drug development and treatment evaluations has been increasingly recognized [7][8][9][10]. In 2005, the US Federal drug agency issued detailed guidance on the use of PROMs in drug trials, emphasizing that patient benefit from a certain drug can only be claimed if this benefit is demonstrated using PROMs.…”

Section: Original Articlementioning

confidence: 99%

Asking the right questions to get the right answers: using cognitive interviews to review the acceptability, comprehension and clinical meaningfulness of patient self-report adverse event items in oncology patients

et al. 2016

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Background: Standardized reporting of treatment-related adverse events (AE) is essential in clinical trials, usually achieved by using the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) reported by clinicians. Patient-reported adverse events (PRAE) may add value to clinician assessments, providing patient perspective on subjective toxicity. We developed an online patient symptom report and self-management system for real-time reporting and managing AE during cancer treatment integrated with electronic patient records (eRAPID). As part of this program we developed a patient version of the CTCAE (version 4.0), rephrasing terminology into a self-report format. We explored patient understanding of these items via cognitive interviews. Material and method: Sixty patients (33 female, 27 male) undergoing treatment were purposively sampled by age, gender and tumor group (median age 61.5, range 35-84, 12 breast, 12 gynecological, 13 colorectal, 12 lung and 11 renal). Twenty-one PRAE items were completed on a touch-screen computer. Subsequent audio-recorded cognitive interviews and thematic analysis explored patients' comprehension of items via verbal probing techniques during three interview rounds (n ¼ 20 patients/ round). Results: In total 33 item amendments were made; 29% related to question comprehension, 68% response option and 3% order effects. These amendments to phrasing and language improved patient understanding but maintained CTCAE grading and key medical information. Changes were endorsed by members of a patient advisory group (N ¼ 11). Conclusion: Item adaptations resulted in a bank of consistently interpreted self-report AE items for use in future research program. In-depth analysis of items through cognitive interviews is an important step towards developing an internationally valid system for PRAE, thus improving patient safety and experiences during cancer treatment.

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Section: Original Articlementioning

confidence: 99%

Asking the right questions to get the right answers: using cognitive interviews to review the acceptability, comprehension and clinical meaningfulness of patient self-report adverse event items in oncology patients

et al. 2016

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“…There is a growing body of opinion that argues that subjective out come measures, such as pain, are more important for patients than profession ally assessed outcome measures. [14][15][16] It is clear that a more lucid understanding of the relationship between radiographi cally judged pathology and subjec tively assessed (patient judged) success of endodontic therapy is required. This information should be supplemented by a greater insight to the full costs and benefits of taking routine outcome radio graphs to inform the future development of guidelines.…”

Section: Discussionmentioning

confidence: 99%

The failure rate of NHS funded molar endodontic treatment delivered in general dental practice

et al. 2008

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VERIFIABLE CPD PAPER• Mandibular first molar root fi llings have low failure rates over a fi ve-year period.• Failure is most likely to occur in the first year following placement of the root fi lling.• Failure rates are similar for optimal versus sub-optimal appearance of root-fi llings on radiographs.• Coronal restoration is an important predictor of survival with crowns performing better than plastic restorations. I N B R I E F RESEARCHObjective To describe the quality and record the outcomes of root canal therapy on mandibular, first permanent molar teeth provided by GDPs working according to NHS contracts. Design Descriptive, retrospective cohort study. Setting Twelve general dental practices in Salford, North West England. Subjects and method All patients aged 20-60 years at tending the practices who had received a NHS-funded root filling in a mandibular first permanent molar between January 1998 and December 2003. The radiographic quality of root fillings in the teeth was assessed by an endodontic specialist and categorised into optimal, suboptimal and teeth which had no radiograph, or an unreadable radiograph. Teeth were also dichotomised into those restored with a crown and those restored with an intracoronal restoration. Failure as an outcome was defined as if a tooth was extracted, the root filling was replaced or periradicular surgery was performed on the tooth. Crude failure rates per 100 years were calculated for optimally, sub-optimally root filled teeth and for those with no or an unreadable radiograph, and according to how the tooth was coronally restored. Survival was assessed using Kaplan-Meier curves and Cox proportional hazards were used to determine factors linked with increased failures. Results One hundred and seventy-four teeth were included in the study, of which 16 failed. The crude failure rates per 100 years with a root filled tooth were very low and differed little (p = 0.9699) for optimally (2.6), sub-optimally (2.5) root filled teeth and for those with no or an unreadable radiograph (2.9), with approximately one in 37 root filled mandibular first molar teeth failing each year. The majority of root fillings fail within the first two years (N = 10, 62.5%). Some 67 teeth (38.5%) were restored with a crown, none of which failed during the follow up period compared to those with a plastic restoration (p = 0.0004). Conclusions The very low failure rates have significant implications for the design of research studies inves tigating outcomes of endodontic therapy. The similar failure rates for teeth that had optimal and suboptimal root fi llings suggest that endodontic treatment is not as technique sensitive as previously thought. The results also support the notion that the coronal restoration is more important than radiographic appearance of the root fi lling.

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“…PROMs have been used in research -as outcomes in clinical trials and economic evaluations -for many years (Appleby et al, 2004;Fung and Hays, 2008;Greenhalgh, 2008;Marshall et al, 2006;Rose and Bezjak, 2009;Snyder and Aaronson, 2009) and have recently migrated into everyday clinical practice (Appleby and Devlin, 2005;Black, 2013;Fung and Hays, 2008;Rothwell et al, 2010;Snyder and Aaronson, 2009).…”

Section: Introductionmentioning

confidence: 99%

An acute knee injury: tracking a two-year recovery online

Taylor

Williams

2015

IJEH

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Current government policy aims to deliver high quality healthcare by recording accurate data at the point of giving care, storing it efficiently and displaying it in a format, which is easily interpreted by healthcare professionals and patients. Few published reports describe the benefits of collecting and reporting such data from the point of view of the patient. We report the case of a 62-year-old lorry driver who used a web-based system to track patient reported outcome measures (PROMs) following an acute knee injury to full recovery over a 24-month period. The system reports clinical outcome scores in real-time to the patient and their medical team, clearly illustrating and enhancing recovery from injury. This case reveals how local software meets the needs of the individual patient linking and integrating such local systems must be the future focus of eHealth within the NHS to release the benefits presented by the information revolution.

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Impact of patient‐reported outcome measures on routine practice: a structured review

Cited by 546 publications

References 54 publications

Asking the right questions to get the right answers: using cognitive interviews to review the acceptability, comprehension and clinical meaningfulness of patient self-report adverse event items in oncology patients

Asking the right questions to get the right answers: using cognitive interviews to review the acceptability, comprehension and clinical meaningfulness of patient self-report adverse event items in oncology patients

The failure rate of NHS funded molar endodontic treatment delivered in general dental practice

An acute knee injury: tracking a two-year recovery online

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