Impact of pharmaceutical care on adherence, hospitalisations and mortality in elderly patients

Abstract

Pharmaceutical care given to our elderly polypharmacy patients made no significant impact on medication adherence, hospitalisation or mortality, when compared to comparable control patients.

Pharmaceutical care in Italy and other European countries: between care and commerce?

“…Many studies have set out to assess the effectiveness of PhC activities for years, and several have shown some positive impact of educational intervention (verbal or written information) on patients' health outcomes compared to non-intervention, mainly by improving compliance and adherence to drug therapy [11,12]. For European studies in particular, we conducted a specific literature search 1 and found seven studies on PhC in the community [13][14][15][16][17][18][19], all from northern countries ( Table 1). Only one study involved general practitioners (in addition to pharmacists) [14], and all but one [16] concluded in favor of PhC and were only co-authored by pharmacists.…”

“…For European studies in particular, we conducted a specific literature search 1 and found seven studies on PhC in the community [13][14][15][16][17][18][19], all from northern countries ( Table 1). Only one study involved general practitioners (in addition to pharmacists) [14], and all but one [16] concluded in favor of PhC and were only co-authored by pharmacists.…”

“…Pharmacist and GP PhC plan in primary care reduces drug-related problems Stuurman-Bieze, 2014 [15] The NL Osteoporosis Pharmacist PhC contributes to more optimal use of osteoporosis medication Olesen, 2014 [16] Denmark Elderly polypharmacy patients Pharmacist PhC has no significant impact on medication adherence, hospitalization or mortality Tommelein, 2014 [17] Belgium Chronic obstructive pulmonary disease Pharmacist PhC improves the pharmacotherapeutic regimen and could reduce hospitalization rates Stuurman-Bieze, 2013 [18] The NL Lipid-lowering therapy patients Pharmacist…”

O Papel Da Atenção Farmacêutica Frente Às Interações Fármaco-Nutriente

“…Além disso, os idosos são propensos a alterações e deficiências nutricionais por distintos fatores como desnutrição e desidratação, hipo-albuminemia e, consequente aumento da fração livre do fármaco, aumento da gordura corporal e redução do tecido muscular, deficiência nutricional de proteínas e micronutrientes, que podem alterar o metabolismo do fármaco; e alterações da função renal, ocasionando risco de toxicidade. As alterações supracitadas podem modificar os efeitos de agentes sedativos, cardiovasculares, diuréticos e outras classes terapêuticas muito utilizadas por idosos (19,20 (21).…”

Effectiveness of a multidisciplinary home‐based medication review program in reducing healthcare utilization among older adult Singaporeans

“…13 Despite ample evidence to support the roles of pharmacists in providing medication management services, studies for home-based medication reviews (HBMR) have shown conflicting results. 5,13,14 In the "Home based medication review" (HOMER) randomized controlled trial (2005), HBMR was counterintuitively associated with a higher rate of hospital admissions, and did not significantly improve quality of life or reduce mortality among elderly patients. 5 The POLYMED study showed cost savings, mainly as a result of reduced prescribing, but no significant improvements were seen in clinical outcomes and quality of life among elderly patients.…”