Impact of Pharmacist Initiated Antimicrobial Stewardship Program ~Evaluation of Antimicrobial Resistance Rate at Three Years after Intervention~

Sasaki, Yasuhiro; Kurishima, Akira; Amano, Misato; Kanamaru, Ayumi; Yamakuchi, Akiko; Takayasu, Hirobumi; Yano, Masataka

doi:10.4058/jsei.35.201

Cited by 1 publication

(1 citation statement)

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“…Prior to this, the pharmacist sorted out the in-hospital adoption of intravenous antimicrobial agents, post-prescription audits and feedback for broad-spectrum antimicrobial agents [ 6 ], as well as actively intervene in blood culture-positive patients [ 7 ]. Mid- to long-term intervention with intravenous antimicrobial agents decreases the resistance rate of Pseudomonas aeruginosa [ 8 ]. AS pharmacists reconsidered their SSI countermeasures after receiving a report from an infection control nurse (ICN), stating that SSI incidence in patients undergoing colorectal cancer surgery was high.…”

Section: Introductionmentioning

confidence: 99%

Evaluation after implementation of chemical bowel preparation for surgical site infections in elective colorectal cancer surgery and role of antimicrobial stewardship pharmacist: Retrospective cohort study

Sasaki,

Kurishima,

Miyamoto

et al. 2024

J Pharm Health Care Sci

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Background We evaluated the predictive factors for surgical site infections (SSIs) in elective colorectal cancer surgery and the role of antimicrobial stewardship (AS) pharmacists in modifying the clinical pathway. Main body Between February 2017 and January 2022, 414 elective colorectal cancer surgeries were performed. The results of multivariate analysis by SSI incidence were adjusted odds ratio (aOR): 0.45; 95% confidence interval (CI): 0.22–0.96 (P = 0.039) for sex (female), aOR: 0.27; 95% CI: 0.13–0.58 (P < 0.001) for laparoscopy, aOR: 0.42; 95% CI: 0.19–0.91 (P = 0.029) for chemical bowel preparation. The median (interquartile range) postoperative length of stay was 12 (10.0–18.5) vs. 10 (9.0–13.0) days before and after the clinical pathway was modified (P < 0.001). Conclusion The role of AS pharmacists was primarily to conduct a literature search to explore whether SSIs could be ameliorated by pharmacotherapy, coordinate the addition of chemical bowel preparation, and epidemiologically confirm their effectiveness.

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Section: Introductionmentioning

confidence: 99%