Impact of polycystic ovary syndrome on eating behavior, depression and health related quality of life: A cross-sectional study in Riyadh

Abstract

Background & objectives Polycystic ovary syndrome (PCOS) is the most common endocrinal disorder, and the greatest cause of infertility in women. Despite availability of individual data on impact of multiple endocrinal, reproductive and even metabolic factors in PCOS individuals, the data on the co-existence of BED and depression in PCOS patients with its relationship on the quality of life in Saudi Arabian females is not found. Hence this study is aimed to elucidate the implication of PCOS on eating behaviour, induction of depression and general health quality in Saudi Arabian population of Riyadh. Materials and methods This is a cross-sectional study carried out in multiple health facilities of Riyadh from January to March 2019. The study samples (494) were recruited by convenience sampling and administered validated questionnaire by trained research participants. The data obtained was analysed by binary logistic regression using SPSS-IBM 25. Results Of the total 494 women participated in the study, 23.48% (116) were PCOS individuals. The odds of developing abnormal health related quality of (HRQ) in patients with PCOS was significantly (P = 0.000, OR = 3.472) high when compared to non-PCOS participants. The odds of showing high binge eating disorder (BED, P = 0.007, OR = 2.856) and depression (P = 0.000, OR = 2.497) scores in PCOS participants were significantly more than patients who were not having PCOS. Out of the three parameters studied, abnormal health related quality of life possessed a higher influence of PCOS compared to depression and abnormal eating behavior. Interpretation & conclusion In conclusion, the present study shows that women with PCOS are at a significant risk for depressive disorders, disorganized eating behavior and impaired quality of life. Therefore, necessary care and screening is required to minimize the impact of PCOS on already burdened individuals.

Role of polycystic ovarian syndrome in developing psychological burden in Saudi Arabian females: A case control study

“…The mood swings in our PCOS group patients could be caused by PCOS-related hyperandrogenism, which can disrupt monoamine balance and contribute to depression in PCOS patients (37). Our findings are consistent with previous reports of PCOS women having a higher incidence of depression (38).…”

Prevalence and associated risk factors for mental health problems among patients with polycystic ovary syndrome in Bangladesh: A nationwide cross—Sectional study

“…Women with PCOS frequently report that they feel less attraction to their sexual life [ 19 ]. These reasons may justify a high divorce rate among women with PCOS [ 20 ]. Therefore, they are more prone to have psychological issues such as anxiety, depression, sadness, and loneliness than others [ 21 , 22 ].…”

Metabolic and Molecular Mechanisms of Diet and Physical Exercise in the Management of Polycystic Ovarian Syndrome

“…First of all, identifying and correcting abnormal eating disorders is a successful strategy in providing weight loss [ 106 ]. In fact, PCOS women are more susceptible to depressive disorders and altered eating behaviors [ 109 ]. Moreover, depression has proved to be a typical tract of PCOS that affects about 40% of these patients [ 110 ] and is responsible for a worse metabolic profile: depression, in fact, is considered an inflammatory disorder and the overlap of symptoms between PCOS and depression suggests that mood modifications would be desirable to achieve better PCOS phenotypes [ 111 ].…”