Impact of porcine circovirus type 2 (PCV2) vaccination on boar semen quality and quantity using two different vaccines

Caspari, Kai; Henning, Heiko; Schreiber, Fernanda; Maass, P.; Gössl, R.; Schaller, Christiane; Waberski, Dagmar

doi:10.1016/j.theriogenology.2014.05.017

Cited by 9 publications

(9 citation statements)

References 30 publications

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“…No significant differences were noticed for the remaining tested indicators between groups. Discussion Previous studies reported that vaccination of mature boars can reduce the virus load and duration of shedding in semen without any major impact on the sperm quality or quantity (Caspari et al 2011). The importance of the presence of PCV2 in semen of premature boars in relation with its quality after puberty is currently unknown and the purpose of this Different superscripts (a, b) denote significant differences between groups (P ≤ 0.05) SP = vaccinated sows -vaccinated piglets group; S = vaccinated sows -unvaccinated piglets group; P = unvaccinated sows -vaccinated piglets group; C = unvaccinated sows -unvaccinated piglets group; SEM -Standard Error of the Mean; VCL -curvilinear velocity (μm/s); VSL-straight line velocity (μm/s); VAP -average path velocity (μm/s); LIN -linearity (VSL/VCL×100); STR -straightness (VSL/VAP×100); WOB -wobble (VAP/VCL×100); ALH -amplitude of lateral head displacement (μm); BCF -beat/cross-frequency (Hz).…”

Section: Resultsmentioning

confidence: 81%

The effect of porcine circovirus type 2 (PCV2) vaccination of male piglets on sperm quality at the age of puberty

et al. 2019

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The objective of the study was to investigate the effect of porcine circovirus type 2 (PCV2) vaccination in piglets on sperm quality of young boars. A total of 136 sows were divided in four groups of 34 animals each (17 vaccinated with Circovac®, Merial and 17 unvaccinated in each group). A total of 1 200 piglets were selected, half of which were vaccinated against PCV2 on the 21st day (Porcilis® PCV, MSD) and the other half was left unvaccinated. Four groups of 300 pigs each were formed as follows: PS group (vaccinated sows + piglets), S group (vaccinated sows + unvaccinated piglets), P group (unvaccinated sows + vaccinated piglets), C group (unvaccinated sows + piglets). Furthermore, 80 boars (20 piglets per group) were selected and slaughtered at the age of 5.5 months and weight of 95 ± 5.5 kg and their epididymal sperm was collected and evaluated for motility and kinetics, concentration and morphology. Additionally, 10 pigs from each group were used for blood sampling and serological testing for PCV2 IgM and IgG antibodies at the age of 21, 70, 110 and 150 days. The IgG and IgM patterns suggested that the piglets were coming into contact with PCV2 early in life. The S group demonstrated significantly lower curvilinear velocity (VCL, μm/s), amplitude of lateral head displacement (ALH, μm) and significantly higher head abnormalities (%) compared to other groups (P < 0.05). In conclusion, vaccinated young boars showed some improved epididymal sperm kinetic indices and head morphology.

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Section: Resultsmentioning

confidence: 81%

The effect of porcine circovirus type 2 (PCV2) vaccination of male piglets on sperm quality at the age of puberty

et al. 2019

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“…The vaccine effectively reduced the incidence of viremia, viral tissue load, shedding, and transmission and promoted the growth of newborn piglets [41,42]. Another study showed that sperm quantity and quality did not alter after vaccination [43]. Subsequently, researchers discovered that Circovac ® could cross-protect pigs against PCV2b and PCV2d challenges, offering the possibility of protection against more PCV2 genotypes [41,44].…”

Section: Pcv2 Inactivated Vaccinementioning

confidence: 99%

Porcine Circovirus Type 2 Vaccines: Commercial Application and Research Advances

Guo

Hou

Zhou

et al. 2022

Viruses

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Porcine circovirus type 2 (PCV2) infection can lead to porcine circovirus-associated disease (PCVAD), causing great economic losses to the global swine industry. Conventional vaccination programs are a major measure in the prevention and control of this disease. Currently, there are 5 commercially available PCV2 vaccines in the international market and 10 kinds commercially available PCV2 vaccines in the Chinese market that confer good efficacy against this virus by alleviating clinicopathological manifestations and enhancing growth performance in pigs. In addition, diverse experimental PCV2 vaccines with protective efficiency have been developed, including attenuated chimeric, nucleic acid, subunit, multivalent, and viral-vectored vaccines. These experimental vaccines have been shown to be relatively effective in improving the efficiency of pig production and simplifying prevention procedures. Adjuvants can be used to promote vaccines with higher protective immunity. Herein, we review the application of multiple commercial vaccines over the years and research advances in experimental vaccines, which provide the possibility for the development of superior vaccines to successfully prevent and control PCV2 infection in the future.

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“…Modified live PRRSv vaccines in Eurpope are registered for use in piglets and sows only, and therefore their effect on semen quality has not been investigated in detail. More recently, vaccination against PCV2 with an oil-based adjuvant vaccine has been reported to cause fever and lethargy that could lead to reduced semen quality [43]. However, this adverse event was only observed in one out of four boars which makes it difficult to draw a conclusion about the safety of oil-based vaccines for use in boars.…”

Section: Managing the Boar: Factors Affecting Semen Production And Qumentioning

confidence: 99%

Boar management and semen handling factors affect the quality of boar extended semen

et al. 2017

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Artificial insemination (AI) is the preferred method for reproduction in the majority of the intensive pig production systems Worldwide. To this end, fresh extended ready-to-use semen doses are either purchased from AI-centres or produced by boars kept on-farm. For profitable semen production, it is necessary to obtain a maximum amount of high quality semen from each boar. This paper reviews current knowledge on factors that may affect semen quality by influencing the boar or the semen during processing.Genetic markers could be used for early detection of boars with the highest fertility potential. Genetic selection for fast growth might jeopardize semen quality. Early detection of boars no longer fit for semen production might be possible by ultrasonography of the testes. Seasonal variation in sperm quality could be associated with changes in photoperiod and heat stress during summer. Comfortable housing, with appropiate bedding material to avoid locomotion problems is essential. In some areas, cooling systems may be necessary to avoid heat stress. The sperm quality can be manipulated by feeding strategies aiming, for instance, to increase sperm resistance to oxidative stress and extend storage duration.High collection frequency will negatively influence sperm quality. Also, if collection is not hygienically performed it will result in bacterial contamination of the semen doses. The concern over bacterial contamination has risen not only because of its negative effect on semen quality but also due to the detection of antimicrobial resistance in isolates from extended semen. Moreover, bacterial and viral pathogens must be monitored because they affect semen production and quality and constitute a risk of herd infection. During processing, boar sperm are submitted to many stress factors that can cause oxidative stress and capacitation-like changes potentially reducing their fertility potential. Dilution rate or dilution temperature affects the quality of the semen doses. Some packaging might preserve semen better than others and some plastic components might be toxic for sperm. Standard operation procedures and quality assurance systems in AI centres are needed.

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Impact of porcine circovirus type 2 (PCV2) vaccination on boar semen quality and quantity using two different vaccines

Cited by 9 publications

References 30 publications

The effect of porcine circovirus type 2 (PCV2) vaccination of male piglets on sperm quality at the age of puberty

The effect of porcine circovirus type 2 (PCV2) vaccination of male piglets on sperm quality at the age of puberty

Porcine Circovirus Type 2 Vaccines: Commercial Application and Research Advances

Boar management and semen handling factors affect the quality of boar extended semen

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