Impact of pre-hospital vital parameters on the neurological outcome of out-of-hospital cardiac arrest: Results from the French National Cardiac Arrest Registry

Javaudin, François; Desce, Natacha; Bastard, Quentin Le; Carvalho, Hugo De; Conte, Philippe Le; Escutnaire, Joséphine; Hubert, Hervé; Montassier, Emmanuel; Leclère, Brice; GR-RéAC,

doi:10.1016/j.resuscitation.2018.09.016

Cited by 16 publications

(9 citation statements)

References 7 publications

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“…The benefit of our study design was that it eliminated the confounding effect of inotropic agents and TTM, which strongly affect hemodynamic levels due to the inconsistent use of inotropic agents and different TTM protocols. Other studies similar to our study reported a relationship between outcomes and early hemodynamic level after resuscitation [ 1 , 3 , 13 ]. However, these studies were conducted on patients with pre-hospital ROSC, and only SBP was addressed.…”

Section: Discussionsupporting

confidence: 88%

“…Targeting higher blood pressure (BP) might theoretically improve cerebral blood perfusion and neurologic outcomes [10]. However, current evidence is not conclusive, and several observational studies have reported controversial results [6,[11][12][13][14][15][16][17]. Recent randomized studies reported no difference in long-term cognitive function, serum neuron-specific enolase level, or brain image findings when targeting higher MBP levels during early postcardiac arrest care [18][19][20].…”

Section: Introductionmentioning

confidence: 99%

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Post-resuscitation diastolic blood pressure is a prognostic factor for outcomes of cardiac arrest patients: a multicenter retrospective registry-based analysis

et al. 2022

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Background Post-resuscitation hemodynamic level is associated with outcomes. This study was conducted to investigate if post-resuscitation diastolic blood pressure (DBP) is a favorable prognostic factor. Methods Using TaIwan Network of Targeted Temperature ManagEment for CARDiac Arrest (TIMECARD) registry, we recruited adult patients who received targeted temperature management in nine medical centers between January 2014 and September 2019. After excluding patients with extracorporeal circulation support, 448 patients were analyzed. The first measured, single-point blood pressure after resuscitation was used for analysis. Study endpoints were survival to discharge and discharge with favorable neurologic outcomes (CPC 1–2). Multivariate analysis, area under the receiver operating characteristic curve (AUC), and generalized additive model (GAM) were used for analysis. Results Among the 448 patients, 182 (40.7%) patients survived, and 89 (19.9%) patients had CPC 1–2. In the multivariate analysis, DBP > 70 mmHg was an independent factor for survival (adjusted odds ratio [aOR] 2.16, 95% confidence interval [CI, 1.41–3.31]) and > 80 mmHg was an independent factor for CPC 1–2 (aOR 2.04, 95% CI [1.14–3.66]). GAM confirmed that DBP > 80 mmHg was associated with a higher likelihood of CPC 1–2. In the exploratory analysis, patients with DBP > 80 mmHg had a significantly higher prevalence of cardiogenic cardiac arrest (p = 0.015) and initial shockable rhythm (p = 0.045). Conclusion We found that DBP after resuscitation can predict outcomes, as a higher DBP level correlated with cardiogenic cardiac arrest.

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Section: Discussionsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Post-resuscitation diastolic blood pressure is a prognostic factor for outcomes of cardiac arrest patients: a multicenter retrospective registry-based analysis

et al. 2022

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“…We selected adults from the French National OHCA Registry, admitted to the hospital. This registry and the OHCA management by a mobile medical team have been previously described [3]. The present study was approved by the French Advisory Committee on Information Processing in Health Research.…”

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confidence: 99%

Improving identification of pulmonary embolism-related out-of-hospital cardiac arrest to optimize thrombolytic therapy during resuscitation

Javaudin

Lascarrou²,

Esquina

et al. 2019

Crit Care

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“…[8,9] S pO 2 , as an indicator that reflects peripheral perfusion, is a vital parameter associated with a better 30day neurological outcome of out-of-hospital cardiac arrest (OHCA). [10] Javaudin et al [10] indicated that SpO 2 ≥94% was associated with a better prognosis in adult OHCA. Our data showed that for all causes of CA, the P ETCO 2 and SpO 2 values in ROSC+ p atients were significantly higher than those in ROSC-patients.…”

Section: Discussionmentioning

confidence: 99%

Factors associated with the clinical outcomes of adult cardiac and non-cardiac origin cardiac arrest in emergency departments: a nationwide retrospective cohort study from China

Wang¹

2023

World J Emerg Med

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Cardiac arrest (CA) is one of the most common causes of death. Despite extensive studies on the management of CA, the global survival rate in adults is only approximately 7%, and 30-day survival is even less than 2% in China. [1] Some studies have shown that CA patients of cardiac and non-cardiac origin may differ in underlying diseases, clinical manifestations, and prognosis, which leads to diff erences in terms of the pathophysiological mechanism and treatment measure. [2,3] However, little is known about the risk factors in relation to the prognosis of CA across arrest etiologies.

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Impact of pre-hospital vital parameters on the neurological outcome of out-of-hospital cardiac arrest: Results from the French National Cardiac Arrest Registry

Cited by 16 publications

References 7 publications

Post-resuscitation diastolic blood pressure is a prognostic factor for outcomes of cardiac arrest patients: a multicenter retrospective registry-based analysis

Post-resuscitation diastolic blood pressure is a prognostic factor for outcomes of cardiac arrest patients: a multicenter retrospective registry-based analysis

Improving identification of pulmonary embolism-related out-of-hospital cardiac arrest to optimize thrombolytic therapy during resuscitation

Factors associated with the clinical outcomes of adult cardiac and non-cardiac origin cardiac arrest in emergency departments: a nationwide retrospective cohort study from China

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