Impact of Pregnancy on Women With Cystic Fibrosis

McMullen, Ann; Pasta, David J.; Frederick, Paul D.; Konstan, Michael W.; Morgan, Wayne J.; Schechter, Michael S.; Wagener, Jeffrey S.

doi:10.1378/chest.129.3.706

Cited by 164 publications

(74 citation statements)

References 11 publications

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“…Similar results have been demonstrated in other recent studies, with women who became pregnant experiencing similar respiratory and health trends as those who did not, although in some reports their utilization of health resources was greater. [32][33][34] Whether or not pregnancy impacts on the trajectory of progression of lung disease for patients with CF, there are physical and emotional demands of child rearing that have the potential to reduce any individual parent's ability to adhere to maintenance therapies themselves. This may lead to a deterioration in their own health.…”

Section: Impact Of Cf On Maternal Outcomesmentioning

confidence: 99%

Pregnancy and cystic fibrosis: Approach to contemporary management

et al. 2014

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Over the previous 50 years survival of patients with cystic fibrosis has progressively increased. As a result of improvements in health care, increasing numbers of patients with cystic fibrosis are now considering starting families of their own. For the health care professionals who look after these patients, the assessment of the potential risks, and the process of guiding prospective parents through pregnancy and beyond can be both challenging and rewarding. To facilitate appropriate discussions about pregnancy, health care workers must have a detailed understanding of the various important issues that will ultimately need to be considered for any patient with cystic fibrosis considering parenthood. This review will address these issues. In particular, it will outline pregnancy outcomes for mothers with cystic fibrosis, issues that need to be taken into account when planning a pregnancy and the management of pregnancy for mothers with cystic fibrosis or mothers who have undergone organ transplantation as a result of cystic fibrosis.

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Section: Impact Of Cf On Maternal Outcomesmentioning

confidence: 99%

Pregnancy and cystic fibrosis: Approach to contemporary management

et al. 2014

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“…Concerns have been raised regarding oral contraceptive pill (OCP) usage in CF due to potential malabsorption, and CF liver disease could result in either high serum levels as a consequence of decreased hydroxylated estrogens or decreased serum levels secondary to decreased glucurconide-conjugated estrogens impairing enterohepatic circulation of estrogens [3,4]. There is no difference in sexual practice between CF and age matched females [5] but pregnancy in CF women is associated with increased health care requirements [6,7] The expert opinion of the U.S. CF Foundation Consensus Statement regarding adult care suggests that "issues of female contraception are broadly similar for women with and without CF" [2]. Evidence in support of this assertion, however, is lacking.…”

Section: Introductionmentioning

confidence: 99%

Contraceptive practices in women with cystic fibrosis

Plant

Goss

Tonelli

et al. 2008

Journal of Cystic Fibrosis

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There is no literature regarding the contraception practices in female CF patients. A chart review identified 69 women with CF of whom two thirds were using contraception. Eleven different forms of contraception were being used with the oral contraceptive pill the preferred method. Despite theoretical concerns regarding efficacy and toxicity, the choices of contraception are similar to those of the general U.S. population.

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“…The health of the CF female would also determine optimal fertility. Pregnancy in CF increases risk for complications, such as exacerbation, hospitalization, and CFRD, but does not necessarily affect long term outcomes, such as lung function or nutrition (McMullen et al, 2006). Many women with CF have had successful pregnancies and outcomes are related to overall health status at baseline.…”

Section: Fertility and Cfmentioning

confidence: 99%

Cystic fibrosis: A clinician's tool for management of care advancing into the adult population

Nast¹,

Paniagua

Anderson

2012

Journal of the American Academy of Nurse Practitioners

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Purpose: To discuss the role of the nurse practitioner in medical management of adult patients with cystic fibrosis (CF). Data sources: A systematic literature review was done by searching online databases: CINAHYL, OVID, and Medline. The Cystic Fibrosis Foundation (CFF) guidelines were reviewed. Tables were compiled for recommended screening and treatment for adult CF patients. Conclusions: Comorbidities occur among adult CF patients and include: CF‐related diabetes (CFRD), fertility issues, CF liver disease (CFLD), and CF bone disease. Diabetes management is reviewed. Current fertility surgical treatments for males and recommendations for females are discussed. Ursodiol is the main treatment regimen for those affected. Bone disease and CF has multiple etiologies and the focus of treatment is based on appropriate vitamin D replacement and bisphosphonates. New standards for vitamin D replacement are discussed. Implications for practice: Clinicians must be familiar with the current treatments and regimens of adults with CF including comorbidities. The CF adult population is expanding and care is extending beyond the CF clinic. More healthcare providers must be educated on the best practices of adult CF care. The importance of early identification and treatment of CF comorbidities cannot be overestimated. To obtain CE credit for this activity, go to http://www.aanp.org and click on the CE Center. Locate the listing for this article and complete the post‐test. Follow the instructions to print your CE certificate. Disclosures  The authors report no competing interests.

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Impact of Pregnancy on Women With Cystic Fibrosis

Cited by 164 publications

References 11 publications

Pregnancy and cystic fibrosis: Approach to contemporary management

Pregnancy and cystic fibrosis: Approach to contemporary management

Contraceptive practices in women with cystic fibrosis

Cystic fibrosis: A clinician's tool for management of care advancing into the adult population

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