2013
DOI: 10.1016/j.bjps.2012.12.019
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Impact of preoperative radiotherapy on head and neck free flap reconstruction: A report on 429 cases

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Cited by 120 publications
(86 citation statements)
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“…Previous retrospective study demonstrated that diabetes, salvage free flap transfer and use of interposition vein grafts were significant factors predicting free flap complications in head and neck reconstruction [11]. Another retrospective study demonstrated that preoperative neck irradiation at doses more than 60 Gy was associated with a significantly increased risk of free flap failure [12]. Therefore, this technique can be performed in selected cases with high risk for free flap transfer including cases described above.…”
Section: Resultsmentioning
confidence: 99%
“…Previous retrospective study demonstrated that diabetes, salvage free flap transfer and use of interposition vein grafts were significant factors predicting free flap complications in head and neck reconstruction [11]. Another retrospective study demonstrated that preoperative neck irradiation at doses more than 60 Gy was associated with a significantly increased risk of free flap failure [12]. Therefore, this technique can be performed in selected cases with high risk for free flap transfer including cases described above.…”
Section: Resultsmentioning
confidence: 99%
“…The effect of radiotherapy on free flap success is still a subject of debate (Choi et al, 2004;Kruse et al, 2010;David et al, 2011;Mucke et al, 2012;Benatar et al, 2013). Shin et al (2012) investigated the influence of postoperative radiotherapy on functional outcome after partial glossectomy with free flap reconstruction.…”
Section: Discussionmentioning
confidence: 99%
“…Several authors found no significant correlation between irradiation and free flap failure, but these authors did not take into account the potential impact of irradiation doses (Choi et al, 2004;Podrecca et al, 2006;Dassonville et al, 2008;Mucke et al, 2012). Benatar et al (2013) investigated the specific effect of irradiation doses over 60 Gy on the outcome of head and neck microvascular reconstruction. Previous neck irradiation at doses over 60 Gy was associated with an increased risk of free flap failure, overall local complications and hematoma (Benatar et al, 2013).…”
Section: Discussionmentioning
confidence: 99%
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“…La prévention de ces nécroses repose sur une indication bien posée et sur la réalisation d'un geste technique adapté et prudent.Bianchi et al considèrent que les pertes de lambeau sont liées à une thrombose veineuse dans 53,3% des cas et à une thrombose artérielle dans 46,7% des cas[4]. patient ayant bénéficié d'une radiothérapie cervicale, la fibrose du réseau veineux receveur conduit souvent à une perméabilité vasculaire précaire et expose d'autant plus au risque de thrombose veineuse, principale étiologie de nécrose des lambeaux libres[9].Dans le cas décrit précédemment, les antécédents de radiothérapie et la pauvreté du réseau veineux cervical secondaire à 2 interventions chirurgicales précédentes nous ont conduit à la réalisation d'une pharyngoplastie par un lambeau antébrachial semi-libre pédiculé en veineux sur la veine céphalique. Il est à noter qu'après chirurgie itérative et radiothérapie, la technique usuelle consiste à anastomoser les pédicules vasculaires sur l'artère carotide externe et/ou la veine jugulaire interne.…”
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