2012
DOI: 10.1055/s-0032-1325406
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Impact of Protein Content on Proton Diffusibility in Intracranial Cysts

Abstract: The strong negative correlation of ADC and MTR values suggest a strong influence of proteins on proton diffusion in intracranial cysts. The phenomena can be explained by macromolecules that bind nearby protons in their vicinity.

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“…In contrast to other studies [13,14,16,19,22,23,62], the benign group contained also complicated cysts, haematomas and intramammary lymph nodes. Such lesions often have low D values [63,64] like malignant lesions, leading to false-positive assignments. Despite the inclusion of such lesions, the accuracy of single parameter D 1 ′ (86.9-88.0%, cutoff 1.23-1.24×10 -3 mm 2 /s) was in the range of other studies (75-91.3%, cutoff 1.01-1.21×10 -3 mm 2 /s) [14,16,17].…”
Section: Discussionmentioning
confidence: 99%
“…In contrast to other studies [13,14,16,19,22,23,62], the benign group contained also complicated cysts, haematomas and intramammary lymph nodes. Such lesions often have low D values [63,64] like malignant lesions, leading to false-positive assignments. Despite the inclusion of such lesions, the accuracy of single parameter D 1 ′ (86.9-88.0%, cutoff 1.23-1.24×10 -3 mm 2 /s) was in the range of other studies (75-91.3%, cutoff 1.01-1.21×10 -3 mm 2 /s) [14,16,17].…”
Section: Discussionmentioning
confidence: 99%