Impact of psychiatric disorders on patient satisfaction after Nissen Fundoplication

Holcomb, Carla N.; Switzer, Noah; Belle, Patricia; McNally, Monet; Perry, Kyle A.

doi:10.1007/s00464-019-06949-x

Cited by 6 publications

(4 citation statements)

References 16 publications

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“…Moreover, the patient's mental state and possible mental illnesses have a significant impact on the patient's satisfaction after anti-reflux surgery. Studies have shown that patients with anxiety show significantly less satisfaction with the procedure than the control group [20]. None of our patients had received psychiatric treatment or were taking psychiatric medications.…”

Section: Discussionmentioning

confidence: 74%

Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study

et al. 2021

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Background and Objectives: Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases. It affects 20% of the adult population and is the third most common cause of chronic cough in adults. This study describes the results of LNF for the relief of GERD-related cough. Materials and Methods: The prospectively collected data on 135 laparoscopic LNF in our department from 2014 to 2018 were reviewed. During consultations, patients were asked about the frequency of symptoms using the GERD Impact Scale (GERD-IS), their satisfaction and recommendation to others, and their general condition after the procedure. Results: We analyzed 23 of 111 patients (20.7%) reporting chronic cough. The mean age was 47 years (range 27–76 years, ±13.9 years) and the mean follow-up time was 48.3 months (range 22.6–76.3 ± 18.05 months). Most patients reported relief from cough after the surgery (78.3%, p < 0.001). Five patients (22%) reported the recurrence of symptoms after a mean of 10.8 months (6–18 months). Seventeen patients (74%) would undergo the surgery again and 18 patients (78%) would recommend the surgery to their relatives. There was a statistically significant improvement in all symptoms from the GERD-IS (p < 0.05). Conclusions: LNF may play an important role in the management of GERD patients with extraesophageal symptoms. After LNF, most of the operated patients reported complete resolution of chronic cough and would recommend the procedure to their relatives.

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Section: Discussionmentioning

confidence: 74%

Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study

et al. 2021

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“…The majority of the recent studies prove the relation between the poor outcome after laparoscopic Nissen fundoplication and psychiatric disorders. Holcomb et al [22] conducted a study about the Impact of psychiatric disorders on patient satisfaction after Nissen Fundoplication and concluded that anxiety and depression affect the patient's satisfaction on the long term follow up. Similarly, Grimsley et al [23] reported that psychological disorders, such as anxiety and depression, can also lead to poor out-come after Nissen fundoplication.…”

Section: Discussionmentioning

confidence: 99%

Predictors of Outcome after Laparoscopic Nissen Fundoplication

El-Atiar,

Almaadawy,

Naroz

et al. 2023

International Journal of Medical Arts

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Article informationBackground: Laparoscopic Nissen fundoplication with posterior hiatal repair is now thought to be the best way to treat severe Gastroesophageal Reflux Disease with surgery [GERD]. Long-term studies have shown that it gives most patients good control of their reflux symptoms and good clinical outcomes. Aim of the work:This study aims to identify the predictive factors of the surgical outcomes of laparoscopic Nissen fundoplication.

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“…In this regard, intensive study of the GERD pathophysiology continues to draw the attention of scientists to the humoral factors that influence the pathogenesis of this disease, and the use of the obtained data to improve the results of both therapeutic and surgical treatment [3,4]. One of the humoral substances of interest is serotonin, which plays a diverse role in the development of various gastrointestinal diseases, including GERD [5,6].…”

Section: є і гайдаржіmentioning

confidence: 99%

“…One of the humoral substances of interest is serotonin, which plays a diverse role in the development of various gastrointestinal diseases, including GERD [5,6]. It is promising to study the dynamics of this hormone both during therapeutic and surgical treatment of various variants of GERD in combination with dyspepsia, anxiety or depressive disorders, as well as the possibility of additional drug effects on serotonin receptors to correct the above disorders and achieve stable recovery after surgical treatment [4,5,6].…”

Section: є і гайдаржіmentioning

confidence: 99%

Serotonin blood level study, anxiety-depressive states indicators and patients life quality after laparoscopic treatment of gastroesophageal reflux disease

Haidarzhi

2024

Pathologia

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Nowadays effective treatment of gastroesophageal reflux disease (GERD) remains a difficult and still unsolved problem. The use of various antisecretory drugs in combination with surgical treatment does not allow to achieve a long lasting improvement of the quality of life and reliable prevention of complications. In this regard, special attention is paid to study humoral factors influencing the pathogenesis of GERD, data on which will improve the results of therapeutic and surgical treatment. It is promising to study the dynamics of serotonin after laparoscopic treatment of various types of GERD, especially in combination with dyspepsia, anxiety or depressive disorders, as well as the possibility of using drugs that affect the metabolism of this hormone to correct the above mentioned disorders and achieve long lasting recovery after laparoscopic fundoplication. The aim of the work was to study the dynamics of serotonin in the blood during laparoscopic total fundoplication and analyze the correlation of this hormone with the psychological well-being of patients before and after surgical treatment of GERD. Materials and methods. Laparoscopic fundoplication by Short Floppy Nissen modification was performed in 35 patients with GERD. There were 26 (74.3 %) women, 9 (25.7 %) men. Age – 55.3 ± 11.3. The comparison group consisted of 20 healthy volunteers (women – 14 (70.0 %); men – 6 (30.0 %), average age – 56.7 ± 10.6), who did not undergo surgery. The groups were comparable by gender and age. The studies were carried out in venous blood plasma, samples of which were maintained using standard methods and stored in a low-temperature freezer at a temperature of -80 °C. Tests for serotonin (Serotonin ELISA, RE59121, IBL) were studied on the immunoenzyme complex ImmunoChem-2100 (USA) of the Department of Clinical Laboratory Diagnostics in the Zaporizhzhia State Medical and Pharmaceutical University. The concentration of the last indicators was expressed in ng/ml. The presence of concomitant anxiety, depression and level of psychological well-being was assessed using the GAD-7, PHQ-9 and SF-36 questionnaires. Statistical assessment of the research results was carried out using the Statistica for Windows 13 software package (StatSoft Inc., No. JPZ804I382130ARCN10-J). Differences were considered statistically significant at p < 0.05. Results. The serotonin level in the blood of practically healthy people was 5.8 ± 1.5 ng/ml. In the main group serotonin values before surgical treatment were 3.1 ± 1.3 ng/ml. After surgical treatment the serotonin level increased to 5.4 ± 1.8 ng/ml and was not statistically different from the level of practically healthy patients. The dynamics of serotonin levels correspond to the dynamics of the patients number with signs of anxiety and depression before and after surgery in the main group, as well as the improvement in the psychological state of patients after surgery compared to preoperative data on the scales of the “psychological component” of SF-36 health questionnaire: Vitality (VT), Social Functioning (SF), Role-Emotional (RE), Mental Health (MH). Conclusions. Laparoscopic crurorrhaphy and fundoplication in the Short Floppy Nissen modification through the mechanism of serotonin helps to improve the psychological state of patients with GERD in the postoperative period, eliminate anxiety and depression, improve quality of life and achieve a lasting antireflux effect. The obtained dynamics of serotonin levels confirms its participation in the formation of behavioral reactions in GERD, helping to improve the results of surgical treatment.

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Impact of psychiatric disorders on patient satisfaction after Nissen Fundoplication

Cited by 6 publications

References 16 publications

Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study

Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study

Predictors of Outcome after Laparoscopic Nissen Fundoplication

Serotonin blood level study, anxiety-depressive states indicators and patients life quality after laparoscopic treatment of gastroesophageal reflux disease

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