“…Through the keyword co-occurrence clustering network analysis (Fig. 11), we can know the main research directions of hypertension combined with atrial fibrillation, that is, the research hotspots include the following 6 aspects: The red cluster is the research direction of heart failure caused by hypertension combined with atrial fibrillation and its echocardiography evaluation and treatment, [32,33] where the high-frequency words include: heart failure, mortality, echocardiography, elderly, prognosis, pulmonary hypertension, complications, coronary artery disease, heart failure with preserved ejection fraction, incidence; The green cluster is the research direction of the mutual influence, prevention and treatment strategies of hypertension combined with atrial fibrillation and stroke, [34,35] where the high-frequency words include: stroke, risk factors, prevalence, ischemic stroke, outcome, dementia, prediction, acute ischemic stroke, intracerebral hemorrhage, transient ischemic attack; The blue cluster is the research direction of diagnosis, treatment and prognosis evaluation of patients with hypertension combined with atrial fibrillation, [36,37] where the highfrequency words include: atrial fibrillation, arrhythmia, catheter ablation, obstructive sleep apnea, ablation, recurrence, COVID-19, meta-analysis, sleep apnea, renal denervation; The yellow cluster is the research direction of risk factors, ablation treatment and exercise intervention of hypertension combined with atrial fibrillation, [38,39] where the high-frequency words include: cardiovascular disease, diabetes mellitus, blood pressure, obesity, myocardial infarction, chronic kidney disease, atherosclerosis, treatment, metabolic syndrome, exercise; The purple cluster is the research direction of the relationship between hypertension-induced cardiac remodeling and atrial fibrillation occurrence and its intervention measures, [40,41] where the high-frequency words include: hypertension, electrocardiography, inflammation, prevention, cardiovascular risk factors, left ventricular hypertrophy, arterial hypertension, left atrium, fibrosis, oxidative stress; The sky blue cluster is the research direction of anticoagulation treatment selection and risk assessment of patients with hypertension combined with atrial fibrillation, [42,43] where the high-frequency words include: anticoagulation, warfarin, bleeding, cha( 2)ds( 2)-vasc score, oral anticoagulation, thromboembolism, atrial flutter, stroke prevention, acute coronary syndrome, cardioversion.…”