The examination of nano-fluid in recent time has been encouraging just as its research interest cuts across some disciplines such as mathematics, mechanical, chemical, civil engineering, physics, earth and natural sciences. Its applicability in the industrial and technological advancement helps in controlling the rate at which heat is conducted and diffuses in a given medium, as well as improving thermal transportation through convection, radiation and conduction. In this work, the analysis of hydromagnetic nano-fluid flow past an inclined heated surface with temperature dependent non-uniform heat source/sink and thermal radiation under heat and mass transmission perspective is considered. Adequate similarity variables are employed in recovering the nonlinear coupled ordinary differential equations (ODEs) from the partial differential equations (PDEs) which describe the equation of the boundary layer. The transformed equations (ODEs) are addressed both analytically and numerically with the aid of regular series approximation technique and Wolfram Mathematica package. The numerically simulated obtained results are graphically presented with legends. The computations opined that velocity declines while energy increases as the magnetic field number enhances. Similarly, improvement on angle of inclination, breeds velocity deceleration. Furthermore, the rate of energy transfer increases as the temperature dependent non-uniform parameters due to thermal generation enhances. In addition, the nanoparticle concentration decreases with increasing values of Schmidt and thermal radiation factors.