Impact of Resistance Training on Factors Involved in the Development of New-Onset Diabetes After Transplantation in Renal Transplant Recipients: An Open Randomized Pilot Study

Karelis, Antony D.; Hébert, Marie‐Josée; Rabasa‐Lhoret, Rémi; Räkel, Agnès

doi:10.1016/j.jcjd.2015.08.014

Cited by 34 publications

(65 citation statements)

References 55 publications

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“…For further qualitative analysis, we extracted data from 11 RCTs and excluded 1 study [17] as it only measured bone mineral density as the primary outcome. Of the 11 RCTs for meta-analysis, aerobic training alone was performed in 2 trials [10,21], resistance training monotherapy was performed in 2 trials [14,16], 6 trials combined aerobic and resistance methods [11,13,15,18,23,24], and 1 trial did not specify the exercise type [22]. For exercise intensity, most trials adopted more than 60% maximum heart rate or maximal oxygen uptake, but 3 studies did not report details on exercise intensity [14,18,22].…”

Section: Resultsmentioning

confidence: 99%

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Effects of exercise training on cardiovascular risk factors in kidney transplant recipients: a systematic review and meta-analysis

Chen

Gao

2019

Renal Failure

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Background: Whether exercise can improve cardiovascular health in kidney transplant recipients (KTRs) is unclear. Therefore, we performed a systematic review of the effects of exercise on cardiovascular risk factors in this population setting. Methods: Randomized control trials (RCTs) evaluating the impact of exercise on major clinical outcomes in KTRs were identified by searches in Cochrane CENTRAL, PubMed, EMBASE, OVID and CBM updated to December 2018. The main outcomes of interest were blood pressure, lipid profile, blood glucose level, arterial stiffness, kidney function, body weight, body mass index, exercise tolerance (VO 2 peak) and quality of life (QOL). Results: After screening 445 studies in the database, we included 12 RCTs in the review and 11 RCTs for further qualitative analysis. The results indicate a significant improvement in small arterial stiffness [mean difference (MD): −1.14, 95% confidence interval (CI): −2.19–0.08, p = .03], VO 2 peak (MD: 2.25, 95% CI: 0.54–3.69, p = .01), and QOL (MD: 12.87, 95% CI: 6.80–18.94, p < .01) after exercise intervention in KTRs. However, there is no evidence for an improvement in blood pressure, lipid profile, blood glucose level, kidney function, body weight or body mass index. Conclusion: Exercise intervention in KTRs improves arterial stiffness but does not consistently contribute to the modification of other CVD risk factors like hypertension, dyslipidemia, hyperglycemia, decreased kidney function and obesity. Exercise also improves exercise tolerance and QOL in KTRs.

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Section: Resultsmentioning

confidence: 99%

“…Five trials investigated a total of 199 participants to judge the effects of exercise on BP [10,11,16,18,24], using different types of exercise training. Both the systolic and diastolic BP were measured during resting.…”

Section: Resultsmentioning

confidence: 99%

Effects of exercise training on cardiovascular risk factors in kidney transplant recipients: a systematic review and meta-analysis

Chen

Gao

2019

Renal Failure

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“…10 Forest plot of the effects of exercise intervention on changes in VO 2 peak for transplant patients (reference [115]) Fig. 11 Forest plot of the effects of exercise intervention on changes in quality of life for transplant patients (reference [115]) Karelis et al 2016 [114,116,118,119]. The outcome index was the SF-36 in some reports and the well-being score in others, but analysis was performed by integrating them.…”

Section: Positions Of Exercise Therapymentioning

confidence: 99%

Clinical practice guideline for renal rehabilitation: systematic reviews and recommendations of exercise therapies in patients with kidney diseases

et al. 2019

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In recent years, a concept of renal rehabilitation has become widely known among nephrology specialists, dialysis specialists, kidney transplantation specialists, rehabilitation specialists, nutrition specialists, guideline specialists, nurses, physiotherapists, and representatives of patients. Therefore, in order to make it clear the definition, methods, and effectiveness of renal rehabilitation in Japan, we launched Renal Rehabilitation Guideline Preparation Committee in 2016 as a part of works in the Japanese Society of Renal Rehabilitation, and created a guideline in accordance to the "Minds Handbook for Clinical Practice Guideline Development 2014". Here, we report systematic reviews and recommendations of exercise therapies in patients with kidney diseases based on the guideline preparation committee works. Six recommendations for the condition of each kidney disorder, groups addressing nephritis/nephrosis, chronic kidney diseases, dialysis therapy, and kidney transplantation were created. All the recommendation grades were determined by a consensus conference participated in by representatives of patients and various professionals. The purpose of this report is to provide an evidence-based, best practice summary to optimize the quality, safety and efficacy, and availability of renal rehabilitation service, and to provide care for maximum patient prognosis, quality of life, and satisfaction.

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“…Of the 47 articles that remained for full-text analysis, 12 were excluded. This left a total of 35[2-5,15-45] articles for inclusion in this review. The study flow and reasons for exclusion are shown in Figure 1.…”

Section: Resultsmentioning

confidence: 99%

Outcomes in randomized controlled trials of exercise interventions in solid organ transplant

Janaudis-Ferreira¹,

Mathur²,

Konidis³

et al. 2016

WJT

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AIMTo identify the outcome measures that have been used in randomized controlled trials (RCTs) of exercise training in solid organ transplant (SOT) recipients and to link these outcomes to the International Classification of Functioning, Disability and Health (ICF) framework.METHODSElectronic literature searches of MEDLINE, EMBASE, CINAHL, Cochrane, Scopus, and Web of Science were performed. We sought RCTs that investigated the effect of exercise training in SOT recipients. Reference lists of all eligible publications were searched for other appropriate studies not identified by the electronic search. A complete list of outcome measures used in the RCTs was generated and each of these was linked to an ICF category.RESULTSFour hundred and thirteen articles were retrieved, of which 35 met our inclusion criteria. The studies included were designed to compare the effects of exercise training programs to usual care or to another exercise training program and reported on recipients of heart (n = 21), kidney (n = 9), lung (n = 3) or liver (n = 2) transplant. Of the 126 outcome measures identified, 62 were used as primary outcome measures. The most commonly occurring primary outcomes were aerobic capacity using the peak VO2 (n = 13), quality of life using the short-form-36 (n = 8), and muscle strength (n = 7). These outcome measures were linked to 113 ICF categories and the majority of outcomes fall into the body function domain (n = 93).CONCLUSIONThere is little standardization in outcome measures used in RCTs of exercise interventions in SOT recipients. The ICF framework can be used to select a core set of outcomes that cross all domains of ICF and that would be appropriate to all SOT recipients.

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Impact of Resistance Training on Factors Involved in the Development of New-Onset Diabetes After Transplantation in Renal Transplant Recipients: An Open Randomized Pilot Study

Cited by 34 publications

References 55 publications

Effects of exercise training on cardiovascular risk factors in kidney transplant recipients: a systematic review and meta-analysis

Effects of exercise training on cardiovascular risk factors in kidney transplant recipients: a systematic review and meta-analysis

Clinical practice guideline for renal rehabilitation: systematic reviews and recommendations of exercise therapies in patients with kidney diseases

Outcomes in randomized controlled trials of exercise interventions in solid organ transplant

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