Impact of risk factors, activities and psychological disorders on the health of patients with chronic obstructive pulmonary disease in China: a cross-sectional study

Abstract

BackgroundPatients with chronic obstructive pulmonary disease (COPD) often have organ dysfunction and resulting poor quality of life; however, in China little information is available regarding factors that affect their health. Here, the relationship between risk factors, activities and psychological disorders and health of patients with COPD in rural areas of Xuzhou, China was assessed.MethodsA cross-sectional study of 7597 COPD patients randomly selected by place of residence from 24,641 COPD patients who had been identified by screening of the 1.10 million health records of all residents of the target area was carried out to evaluate the relationships between risk factors, activities, psychological disorders and the ADO index (age, dyspnea, and airflow obstruction). The participants were assessed by spirometry and by administering a newly designed face-to-face questionnaire, which included items on general factors, risk factors, activities and psychological disorders. Correlations between the ADO index and the items addressed by the questionnaire were calculated.ResultsThe mean score of the ADO index was 3.7 ± 1.6. The ADO indices of current smokers, ex-smokers, and non-smokers were 3.9 ± 2.1, 3.7 ± 1.9, and 3.2 ± 1.5, respectively (P < 0.001). The ADO indices of cooks and non-cooks were 4.0 ± 2.2 and 3.5 ± 1.7, respectively (P < 0.001). The correlation coefficient between self-assessment of health status and ADO index was 0.976 (P < 0.001). Only 5.7% of patients reported no limitation of their daily living activities. The correlation coefficient between daily living activities and ADO index was 0.981 (P < 0.001). Only 5.5% of patients reported no limitation of social activities. The correlation coefficient between social activities and ADO index was 0.989 (P < 0.001), between the assessed anxiety score and ADO index 0.972 (P < 0.001), and between the assessed depression score and ADO index 0.989 (P < 0.001).ConclusionsCOPD severity was significantly correlated with behavior (especially regarding smoking and cooking with biofuel in confined spaces), physical strength, daily living activities, social activities, anxiety and depression. Comprehensive approaches are required for the prevention and treatment of COPD.

Psychometric properties of the Anxiety Inventory for Respiratory Disease in patients with COPD in China

“…Previous reviews indicated that up to 55% of patients with COPD may have a clinical anxiety disorder 8,9. One cross-sectional study in China showed the prevalence of anxiety at approximately up to 57.1% 10. Despite the high prevalence of anxiety in patients with COPD, it is often neglected and undermanaged 11.…”

Frequent Exacerbator: The Phenotype at Risk of Depressive Symptoms in Geriatric COPD Patients

“…In Lou et al's study [30] of 1100 COPD patients conducted in Xuzhou, the prevalence rate of depression in COPD patients was 18.3 % as measured by the Hospital Anxiety and Depression Scale (HADS). In rural China, Zhang et al's study [31] showed that 28.3 % of COPD patients had depressive symptoms as screened by the study questionnaire. Similar prevalence rate of depressive symptoms (22.8 %) was observed in Chinese COPD patients in a Singaporean study [32] that used GDS as a screening tool.…”

“…In the above studies [21,[29][30][31][32][33], the mean age of COPD subjects ranged from 59 to 65 years. In contrast, majority of COPD patients in our study were from geriatric population (mean age 75 years).…”

Smoking, aging, and expression of proteins related to the FOXO3 signaling pathway in lung tissues

“…In developing countries such as China, the high incidence of COPD is a major public health concern (Zhou and Chen, 2013;Zhang et al, 2013). COPD is correlated with various factors, including infection, genetics, and environmental exposure (particularly cigarette smoke).…”