Impact of rotavirus vaccine introduction and genotypic characteristics of rotavirus strains in children less than 5 years of age with gastroenteritis in Ethiopia: 2011–2016

Abebe, Almaz; Getahun, Mekonen; Seheri, Mapaseka L; Beyene, Berhane; Assefa, Essete; Teshome, Birke; Tefera, Mesfin; Kebede, Ferehiwot; Habtamu, Abebe; Hailemariam, Tewodros; Mphahlele, M. Jeffrey; Teshager, Fasil; Ademe, Ayesheshem; Teka, Telahun; Weldegebriel, Goitom; Mwenda, Jason M.

doi:10.1016/j.vaccine.2018.09.048

Cited by 12 publications

(12 citation statements)

References 29 publications

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“…The result showed no significant difference in the prevalence of rotavirus infection between the pre-vaccine introduction 24% (95% CI: 23, 25) and post-vaccine introduction 21% (95% CI = 19, 23) periods (Figures 6 and 7). [16][17][18][19][20][21][22][23][24][25][26]. The red line represents the minimum possible prevalence value (0).…”

Section: Studies Included In Quantitative Synthesismentioning

confidence: 99%

“…Yassin (2012) Ramos (2015) Abebe (2014) Bizuneh (2004) Abebe (2018) Mwenda ( Figure 6. Forest plot of pooled prevalence estimates of rotavirus infection before the introduction of rotavirus vaccine among under-five children with acute gastroenteritis in Ethiopia, 2019 [16,17,19,20,[23][24][25][26]. The red line represents the minimum possible prevalence value (0).…”

Section: Studies Included In Quantitative Synthesismentioning

confidence: 99%

“…Mixed G and P types were also reported from diarrheic children. [16,17,19,20,[23][24][25][26]. The red line represents the minimum possible prevalence value (0).…”

Section: Genotype Diversity Of Rotavirus In Ethiopiamentioning

confidence: 99%

“…The blue diamond represents the 95% confidence interval of the pooled rotavirus prevalence estimate. [18,19,21,22]. The red line represents the minimum possible prevalence value (0).…”

Section: Genotype Diversity Of Rotavirus In Ethiopiamentioning

confidence: 99%

“…The blue diamond represents the 95% confidence interval of the pooled rotavirus prevalence estimate. [16,19,21,25,26]. n = 719 in (A), n = 719 in (B).…”

Section: Genotype Diversity Of Rotavirus In Ethiopiamentioning

confidence: 99%

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Prevalence and Genetic Diversity of Rotaviruses among under-Five Children in Ethiopia: A Systematic Review and Meta-Analysis

Damtie

Melku

Tessema

et al. 2020

Viruses

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Rotavirus infection is the major cause of acute gastroenteritis among children globally. Sub-Saharan Africa including Ethiopia is disproportionally affected by the disease. The aims of this review were to determine the pooled prevalence of rotavirus infection among children under-five and to identify the dominant rotavirus genotypes in Ethiopia. Twelve studies were included to estimate the pooled prevalence of rotavirus acute gastroenteritis and five studies were used to determine predominantly circulating genotypes of rotavirus. The pooled prevalence of rotavirus infection was 23% (95% CI = 22%–24%). G3 (27.1%) and P[8] (49%) were the dominant G and P types, respectively. The G8 G-type uncommon in humans but highly prevalent in cattle was also reported accounting for 1% of all cases. The major G/P combinations were G12P[8] (15.4%), G3P[6] (14.2%), G1P[8] (13.6%) and G3P[8] (12.9%) collectively accounting for 56.1% of rotavirus strains. Similar to other parts of the world, the dominance of G1, G3, P[6] and P[8] genotypes was noted in Ethiopia. The increased prevalence of G12P[8] strains observed in Ethiopia was similar to observations in other geographic regions in the post-vaccine introduction period. Thus, further studies are required on the vaccine effectiveness, genotype distribution and inter-species transmission potential of rotaviruses in Ethiopia.

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Section: Studies Included In Quantitative Synthesismentioning

confidence: 99%

Section: Studies Included In Quantitative Synthesismentioning

confidence: 99%

“…Mixed G and P types were also reported from diarrheic children. [16,17,19,20,[23][24][25][26]. The red line represents the minimum possible prevalence value (0).…”

Section: Genotype Diversity Of Rotavirus In Ethiopiamentioning

confidence: 99%

“…The blue diamond represents the 95% confidence interval of the pooled rotavirus prevalence estimate. [18,19,21,22]. The red line represents the minimum possible prevalence value (0).…”

Section: Genotype Diversity Of Rotavirus In Ethiopiamentioning

confidence: 99%

“…The blue diamond represents the 95% confidence interval of the pooled rotavirus prevalence estimate. [16,19,21,25,26]. n = 719 in (A), n = 719 in (B).…”

Section: Genotype Diversity Of Rotavirus In Ethiopiamentioning

confidence: 99%

See 3 more Smart Citations

Prevalence and Genetic Diversity of Rotaviruses among under-Five Children in Ethiopia: A Systematic Review and Meta-Analysis

Damtie

Melku

Tessema

et al. 2020

Viruses

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Genomic characterization of uncommon human G3P[6] rotavirus strains that have emerged in Kenya after rotavirus vaccine introduction, and pre-vaccine human G8P[4] rotavirus strains

Wandera

Komoto

Shah

et al. 2019

Infection, Genetics and Evolution

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Full genome characterization of human G3P[6] and G3P[9] rotavirus strains in Lebanon

Mishra

Reslan

El-Husseini

et al. 2020

Infection, Genetics and Evolution

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Impact of rotavirus vaccine introduction and genotypic characteristics of rotavirus strains in children less than 5 years of age with gastroenteritis in Ethiopia: 2011–2016

Cited by 12 publications

References 29 publications

Prevalence and Genetic Diversity of Rotaviruses among under-Five Children in Ethiopia: A Systematic Review and Meta-Analysis

Prevalence and Genetic Diversity of Rotaviruses among under-Five Children in Ethiopia: A Systematic Review and Meta-Analysis

Genomic characterization of uncommon human G3P[6] rotavirus strains that have emerged in Kenya after rotavirus vaccine introduction, and pre-vaccine human G8P[4] rotavirus strains

Full genome characterization of human G3P[6] and G3P[9] rotavirus strains in Lebanon

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Impact of rotavirus vaccine introduction and genotypic characteristics of rotavirus strains in children less than 5 years of age with gastroenteritis in Ethiopia: 2011–2016

Cited by 12 publications

References 29 publications

Prevalence and Genetic Diversity of Rotaviruses among under-Five Children in Ethiopia: A Systematic Review and Meta-Analysis

Prevalence and Genetic Diversity of Rotaviruses among under-Five Children in Ethiopia: A Systematic Review and Meta-Analysis

Genomic characterization of uncommon human G3P[6] rotavirus strains that have emerged in Kenya after rotavirus vaccine introduction, and pre-vaccine human G8P[4] rotavirus strains

Full genome characterization of human G3P[6] and G3P[9] rotavirus strains in Lebanon

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Impact of rotavirus vaccine introduction and genotypic characteristics of rotavirus strains in children less than 5 years of age with gastroenteritis in Ethiopia: 2011–2016