Impact of rotavirus vaccines in low and middle-income countries

Sindhu, Kulandaipalayam Natarajan; Babji, Sudhir; Ganesan, Santhosh Kumar

doi:10.1097/qco.0000000000000397

Cited by 15 publications

(12 citation statements)

References 88 publications

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“…Second, data on diarrhoea-related hospital admissions and deaths were not available at this time due to delays when collecting information at national level. These data require further study considering the well-known impact that rotavirus vaccination produces on severe diarrhoea cases [7, 8, 29, 30]. Third, due to the procedures of data collection, we were not able to further disaggregate the 1–4 years sub-group.…”

Section: Discussionmentioning

confidence: 99%

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First assessment of all-cause acute diarrhoea and rotavirus-confirmed cases following massive vaccination in Argentina

Degiuseppe

Stupka

2018

Epidemiol. Infect.

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Argentina incorporated rotavirus massive vaccination in 2015. No specific strategy has been designed to accurately measure the impact of this recent introduction on the diarrhoeal disease burden in our country. We assessed post-vaccine introduction data (all-cause acute diarrhoea and rotavirus laboratory-confirmed cases, and genotype distribution), compared with pre-vaccination period in children under 5 years of age in Argentina. Cross-sectional ecologic analysis was conducted with data from the Argentine Surveillance Health System. Endemic channel and global and seasonal incidence rates of pre- and post-vaccination periods were calculated and further compared. Conventional binary genotypification on rotavirus-positive samples was also performed. In post-vaccination period, a global decrease of 20.8% in the rate of all-cause acute diarrhoea cases was found. The endemic channel showed that declination was more significant in the autumn/winter season. Rotavirus laboratory-confirmed cases showed 61.7% of reduction and the weekly distribution analyses indicated a significant flattening of the expected seasonal peak. G2P[4] was the most prevalent circulating genotype (57.2%). This study represents the first assessment of diarrhoeal disease burden since rotavirus massive vaccination strategy was implemented in Argentina. This introduction represented a successful intervention due to the significant decrease in all-cause acute diarrhoea cases and rotavirus laboratory-confirmed cases.

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Section: Discussionmentioning

confidence: 99%

“…Since vaccine approval and licensing in 2006, the rotavirus massive vaccination strategy has been considered the most effective public health measure for reducing this disease burden [6][7][8]. Therefore, the World Health Organization has been continuously encouraging countries to include it in their National Immunization Programmes [9].…”

Section: Introductionmentioning

confidence: 99%

First assessment of all-cause acute diarrhoea and rotavirus-confirmed cases following massive vaccination in Argentina

Degiuseppe

Stupka

2018

Epidemiol. Infect.

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“…Furthermore, administration of these vaccines in humans has yielded some positive results as revealed in a few studies that reported reduction in human exposure to rotavirus in some LMICs (Armah et al., ; Bar‐Zeev et al., ; Schwartz et al., ). Notwithstanding, rotavirus vaccines are not yet widely available in some LMICs (Motayo, Faneye, & Adeniji, ; Sindhu, Babji, & Ganesan, ). Contrary to the case of rotavirus, development of norovirus vaccines is still ongoing (Hallowell, Parashar, & Hall, ; Riddle, Chen, Kirkwood, & MacLennan, ), and thus a licensed norovirus vaccine is currently unavailable (Huys, Grau, & Karst, ).…”

Section: Viruses In Rtes From Lmicsmentioning

confidence: 99%

Microbiological safety of ready‐to‐eat foods in low‐ and middle‐income countries: A comprehensive 10‐year (2009 to 2018) review

Makinde

Ayeni

Sulyok

et al. 2020

Comp Rev Food Sci Food Safe

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Ready‐to‐eat foods (RTEs) are foods consumed without any further processing. They are widely consumed as choice meals especially by school‐aged children and the fast‐paced working class in most low‐ and middle‐income countries (LMICs), where they contribute substantially to the dietary intake. Depending on the type of processing and packaging material, RTEs could be industrially or traditionally processed. Typically, RTE vendors are of low literacy level, as such, they lack knowledge about good hygiene and food handling practices. In addition, RTEs are often vended in outdoor environments such that they are exposed to several contaminants of microbial origin. Depending on the quantity and type of food contaminant, consumption of contaminated RTEs may result in foodborne diseases and several other adverse health effects in humans. This could constitute major hurdles to growth and development in LMICs. Therefore, this review focuses on providing comprehensive and recent occurrence and impact data on the frequently encountered contaminants of microbial origin published in LMICs within the last decade (2009 to 2018). We have also suggested viable food safety solutions for preventing and controlling the food contamination and promoting consumer health.

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“…In addition, continued monitoring will allow for the characterization of the evolving epidemiology of rotavirus genotypes.In countries that do not offer rotavirus vaccination through NIPs and have high RVGE disease burden and mortality, there is great potential to mitigate severe disease and deaths through the introduction of a rotavirus vaccination program. Experience from a varied range of geographic and socioeconomic settings, especially from countries in Africa, provides evidence that substantiates the effectiveness of their respective NIPs[104]. Such evidence gained through continued monitoring can be used to inform rotavirus vaccine implementation in Asia and the Pacific regions.…”

mentioning

confidence: 94%

A review of rotavirus vaccine use in Asia and the Pacific regions: challenges and future prospects

Buchy¹,

Chen²,

Zhang³

et al. 2021

Expert Review of Vaccines

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Impact of rotavirus vaccines in low and middle-income countries

Cited by 15 publications

References 88 publications

First assessment of all-cause acute diarrhoea and rotavirus-confirmed cases following massive vaccination in Argentina

First assessment of all-cause acute diarrhoea and rotavirus-confirmed cases following massive vaccination in Argentina

Microbiological safety of ready‐to‐eat foods in low‐ and middle‐income countries: A comprehensive 10‐year (2009 to 2018) review

A review of rotavirus vaccine use in Asia and the Pacific regions: challenges and future prospects

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