Abstract:BackgroundVancomycin is commonly used to treat acute pulmonary exacerbations in pediatric patients with cystic fibrosis (CF) and a history of methicillin‐resistant Staphylococcus aureus. Optimizing vancomycin exposure during therapy is essential and area under‐the‐curve (AUC)‐guided dosing is now recommended. Model‐informed precision dosing (MIPD) utilizing Bayesian forecasting is a powerful approach that can support AUC‐guided dose individualization. The objective of the current study was to examine the impac… Show more
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