The present work is devoted to studying the characteristics of the spatiotemporal microearthquake distribution in the Lena Delta using data from local seismological monitoring conducted from 2016 to 2018. The results revealed the confinement of microearthquake sources to the Olenek segment of the Lena–Taimyr zone of boundary uplifts, marking the boundary of the Siberian Platform and the Laptev Sea Rift System. The Olenek segment fault zone is traced by hypocenters up to the Moho at a depth of about 40 km. Microearthquakes are distributed unevenly in both space and time, forming clusters in different parts of the fault zone. These clusters can be interpreted as originating from unstable stick-slip sliding during the process of background stable creeping. Seasonal variability in the number of recorded weak earthquakes in the Lena Delta has been revealed. An extended regional catalog (2003–2022) was also used to analyze the seasonal seismicity modulation. The average number of events per day increases by approximately a factor of two during cold seasons. Comparison of these results with snow cover thickness, the Lena water level, GNSS data, gravity data, and calculated additional Coulomb stresses revealed that the seasonal seismicity increase in the Lena Delta correlates with the positive additional Coulomb stresses under conditions of prevalence of normal faults in the Olenek segment. Additional Coulomb stress directly depends on equivalent water thickness, which, in turn, correlates with snow cover thickness. The summer flood does not have a significant impact on the seismicity rate, presumably due to its short duration.