Impact of Seminal Plasma Trace Elements on Human Sperm Motility Parameters

Hashemi, Mohammad; Behnampour, Nasser; Nejabat, Mojgan; Tabandeh, A; Ghazimoghaddam, B.; Joshaghani, Hamidreza

doi:10.1515/rjim-2017-0034

Cited by 24 publications

(28 citation statements)

References 21 publications

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“…According to El Aaleba's et al findings showed that PE patients had lower levels of seminal plasma Mg levels in comparison to healthy men alongside with similar results about the seminal levels of Mg levels in PE patients. Higher levels of Mg in normozoospermic males compared to asthenozoospermic males were observed in Hashemi's et al results, which can be suspected to affect sperm motility [77].…”

Section: Magnesiummentioning

confidence: 67%

“…As far as the copper is concerned, there is a some kind of inconstancy in several trial's findings. Eidi et al [75] and Yan Li et al [76] reported a negative correlation between semen quality and Cu levels (Cu was considered as an environmental chemical pollutant for the workers of the industrial factory in the study of Li et al), whilst in the study of Hashemi et al [77], significantly lower levels of Cu was observed in the seminal fluid of asthenozoospermic subjects in comparison to normozoospermic men not exposed to poisonous amounts of Cu.…”

Section: Coppermentioning

confidence: 99%

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An impact of selected micronutrients on fertility

Żak

Leziak

Niedobylski

et al. 2020

J Educ Health Sport

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Introduction and purpose: The problem with infertility affects between 8 and 12% of reproductive-aged couples. Among the reasons, smoking, adulterated food, hormonal disorder are featured. Our purpose is to check how micronutrients impact fertility. Brief description of the state of knowledge: Micronutrients deficiency, specifically zinc and selenium deficiencies have also unpropitious impact on fertility. In this review, the potential role of these microelements in male and female reproductive health is considered. Zinc had been proved to regulate sperm motility, spermatogenesis and reduce oxidative stress. Lower delivery of selenium decrease testosterone level by causing changes in receptor of the luteinising hormone. It is also compared with lower spermatozoa concentration. In this review the role of iron, manganese, lead, nickel, copper, magnesium and cobalt is described as well. Summary: Deficiencies of some micronutrients may make worse the fertility. That's the reason why additional supplementation may be important in the treatment of infertility.

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Section: Magnesiummentioning

confidence: 67%

Section: Coppermentioning

confidence: 99%

An impact of selected micronutrients on fertility

Żak

Leziak

Niedobylski

et al. 2020

J Educ Health Sport

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“…The excess or the deficiency may lead to defective spermatogenesis and to fertility impairment [6]. About this topic, Hashemi et al [7] reported a negative impact of iron on human sperm motility.…”

Section: Introductionmentioning

confidence: 99%

Semen Biochemical Components in Varicocele, Leukocytospermia, and Idiopathic Infertility

et al. 2020

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The evaluation of the seminal plasma plays a relevant role in the definition of male infertility and in assisted reproduction outcomes; for this reason, it would be recommended to find biochemical markers able to characterize sperm pathology. In this study, 53 infertile patients (grouped by the presence leukocytospermia, idiopathic infertility, or varicocele) and 10 fertile men were selected. Spermiogram was performed by light microscopy, and sperm ultrastructure was evaluated by transmission electron microscopy (TEM) mathematically elaborated. Testosterone (TESTO), estradiol (E2), ferritin (FERR), iron (Fe), transferrin (TRSF), triglycerides (TRG), cholesterol (CHOL), and isoprostanes (F 2-IsoPs) were detected in seminal plasma. Sperm characteristics and biochemical components were correlated by Spearman's rank correlation coefficient in the whole population and in each group. The levels of TESTO and E2 were positively correlated with sperm quality in particular, and E2 was correlated with fertility index expressing the number of sperm free of ultrastructural defects evaluated by TEM. On the contrary, the indices of iron metabolism (FERR, Fe, and TRSF) were positively associated with low sperm quality and sperm necrosis, particularly in leukocytospermia and varicocele groups, pathologies in which an inflammatory status and oxidative stress condition are present. The study of the seminal plasma composition deserves attention because the levels of the various components seem to be associated with specific reproductive pathologies.

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“…FRA is a glycaemic biomarker used to indicate DM (Lee, 2015) and is associated with the fertilisation process (Tomaszewski et al, 1992). Although imbalances in the biochemical components of seminal plasma have been demonstrated in male with fertility disorders (Hashemi et al, 2018), the alterations of seminal protein markers, MG and FRA in T1DM and T2DM have never been investigated. Many seminal proteins have been identified in different species (stallion: seminal plasma protein 1; cattle: spermadhesin Z13, heparin-binding proteins, osteopontin and phospholipase A2 isoforms; human: stabilin 2, centrosomal proteins, guanine nucleotide-releasing factors and prolactin-inducible proteins) as described previously (Brandon, Heusner, Caudle, & Fayrer-Hosken, 1999;Chacur, 2012;Moura, Koc, Chapman, & Killian, 2006;Yamakawa, Yoshida, Nishikawa, Kato, & Iwamoto, 2007).…”

Section: Introductionmentioning

confidence: 99%

Alterations of morphology and phosphorylated protein expression in the seminal vesicles of diabetic mice

Yannasithinon

Iamsaard

2019

Andrologia

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Although many studies reported the detrimental effects of type 1 and 2 diabetes mellitus (T1DM and T2DM) on testis, reproductive parameter changes in DM seminal vesicles have never been documented. This study aimed to examine the morphology, biochemical levels and tyrosine phosphorylation in seminal vesicles of T1DM and T2DM mice. Fifty-six male C57BL/6 mice were divided into four groups (n = 14/each): T1DM control, T1DM, T2DM control and T2DM. T1DM mice were daily injected of streptozotocin (STZ; 40 mg/kg BW) for 5 days. T2DM mice received high-fat diet for 14 days prior to STZ injection at a single dose (85 mg/kg BW). At the end of experiments (days 36 and 72), magnesium (MG) and fructosamine (FRA) levels, and phosphorylated protein expression in seminal vesicle were examined. The results showed that seminal and prostate weights and MG and FRA levels of T1DM animals were significantly increased as compared to T2DM mice. Some seminal histopathologies and decreased epithelial height were observed in both DM groups. Significantly, a 72-kDa phosphorylated protein expression was increased in DM seminal vesicle. We concluded that changes of biochemical components and phosphorylated proteins in seminal vesicle of T1DM and T2DM mice may be associated with low-quality seminal plasma. K E Y W O R D Sbiochemical components, diabetes mice, streptozotocin, tyrosine-phosphorylated protein

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Impact of Seminal Plasma Trace Elements on Human Sperm Motility Parameters

Cited by 24 publications

References 21 publications

An impact of selected micronutrients on fertility

An impact of selected micronutrients on fertility

Semen Biochemical Components in Varicocele, Leukocytospermia, and Idiopathic Infertility

Alterations of morphology and phosphorylated protein expression in the seminal vesicles of diabetic mice

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