Impact of short-course radiotherapy and low anterior resection on quality of life and bowel function in primary rectal cancer

Murata, Ariana; Brown, C. J.; Raval, Manoj J.; Phang, P. Terry

doi:10.1016/j.amjsurg.2007.12.034

Cited by 29 publications

(11 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In an earlier publication, we reported that radiotherapy has an independent negative influence on fecal incontinence in patients treated with low anterior resection. 19 A third patient in the present study had follow-up of …”

Section: Discussionmentioning

confidence: 99%

Transanal endoscopic microsurgery: impact on fecal incontinence and quality of life

Planting

Phang²,

Raval³

et al. 2013

cjs

Self Cite

View full text Add to dashboard Cite

Background: Anal dilation during tumour excision with transanal endoscopic microsurgery (TEM) has caused concerns regarding postoperative anal function. We sought to determine whether TEM affects anorectal function and quality of life. Results: Forty patients received TEM; 30 of them met all inclusion criteria and agreed to participate. The median age was 70 (42-93) years, and median follow-up time between the interview and the operation was 365 (55-712) days. Tumours excised included 19 adenomas, 8 carcinomas and 3 carcinoid tumours. The median distance from the tumour to the anal verge was 6.5 (2-13) cm. Median length of stay was 1 (0-12) day. For most aspects of quality of life, there were no detectable differences after surgery. The EORTC QLQ-C30 showed a significant improvement in diarrhea (27.8 v. 10, p = 0.002). The FIQL scores improved with surgery (3.59 v. 3.85, p = 0.020). There was no difference in pre-versus postoperative FISI scores (6.7 v. 6.3, p = 0.93). Methods Conclusion:Despite a large operating rectoscope, TEM improves quality of life related to fecal incontinence and does not have a negative impact on fecal continence.Contexte : La dilatation de l'anus au cours de l'excision d'une tumeur par microchirurgie endoscopique transanale (MET) soulève des préoccupations quant à la fonction anale postopératoire. Nous avons cherché à déterminer si la MET a un effet sur la fonction anorectale et la qualité de vie.

show abstract

Section: Discussionmentioning

confidence: 99%

Transanal endoscopic microsurgery: impact on fecal incontinence and quality of life

Planting

Phang²,

Raval³

et al. 2013

cjs

Self Cite

View full text Add to dashboard Cite

show abstract

“…10 A small number of studies have not been bound by these limitations, using validated instruments to examine LARS more comprehensively, beyond fecal incontinence. [11][12][13][14][15] The Low Anterior Resection Syndrome Score (LARS score) is 1 such instrument. 16 It is a concise questionnaire designed for quick evaluation of a diverse range of LARS symptoms that patients find the most bothersome, and is suitable for routine use in clinical settings.…”

Section: Introductionmentioning

confidence: 99%

Bowel Function 14 Years After Preoperative Short-Course Radiotherapy and Total Mesorectal Excision for Rectal Cancer: Report of a Multicenter Randomized Trial

Chen

Wiltink

Nout

et al. 2015

Clinical Colorectal Cancer

260

177

View full text Add to dashboard Cite

show abstract

“…Since recommended adjuvant therapy [20][21][22][23][24][25][26][27] can not only decrease HRQL due to side effects [28,29] but also improve HRQL due to better expected health outcomes [30], adjuvant therapy must also be considered. The objective of this study is to investigate rectal cancer patients' postoperative HRQL based on a broad multidimensional interpretation of HRQL using the FACT-C in a prospective population-based cohort.…”

Section: Introductionmentioning

confidence: 99%

Quality‐of‐life and surgical treatments for rectal cancer—a longitudinal analysis using the California Cancer Registry

et al. 2010

View full text Add to dashboard Cite

Background-Heterogeneous results for research investigating health-related quality of life (HRQL) in patients undergoing sphincter-ablating procedures for rectal cancer are likely due to single institution experiences and measurement of HRQL. To address this heterogeneity, we evaluated HRQL in patients with rectal cancer by type of surgery, location of tumor and receipt of adjuvant therapy using an HRQL instrument that has not been used to address rectal cancer patients in a population-based sample over time.

show abstract

Impact of short-course radiotherapy and low anterior resection on quality of life and bowel function in primary rectal cancer

Cited by 29 publications

References 28 publications

Transanal endoscopic microsurgery: impact on fecal incontinence and quality of life

Transanal endoscopic microsurgery: impact on fecal incontinence and quality of life

Bowel Function 14 Years After Preoperative Short-Course Radiotherapy and Total Mesorectal Excision for Rectal Cancer: Report of a Multicenter Randomized Trial

Quality‐of‐life and surgical treatments for rectal cancer—a longitudinal analysis using the California Cancer Registry

Contact Info

Product

Resources

About