Impact of surgery on fertility among patients with deep infiltrating endometriosis

Raos, Maja; Mathiasen, Mie; Seyer‐Hansen, Mikkel

doi:10.1016/j.ejogrb.2022.12.004

Cited by 8 publications

(8 citation statements)

References 24 publications

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“…A 2023 retrospective study of nearly 200 women with DIE and pregnancy intention who underwent rectosigmoid resection found that 65% of patients conceived with ART following surgery [47 ▪▪ ]. In this study, the authors report a 16.6% Clavien–Dindo grade III complication rate, most commonly anastomotic leak or ureteral injury.…”

Section: Impact Of Surgery On Fertility For Deep Infiltrating Endomet...mentioning

confidence: 78%

“…ESHRE states that the effectiveness of surgical excision of deep nodular lesions before ART is not well established [28]. Since the publication of these guidelines, additional small cohort studies of fertility patients suggest potential benefit for surgical management of DIE prior to ART treatments [42–44,45,46 ▪▪ ,47 ▪▪ ].…”

Section: Impact Of Surgery On Fertility For Deep Infiltrating Endomet...mentioning

confidence: 99%

“…In this study, the authors report a 16.6% Clavien–Dindo grade III complication rate, most commonly anastomotic leak or ureteral injury. Interestingly, the pregnancy and live birth rates following surgery were not impacted by the presence of a surgical complication [47 ▪▪ ]. Surgery for endometriosis involving the bowel requires a high level of surgeon skill and often a multidisciplinary approach.…”

Section: Impact Of Surgery On Fertility For Deep Infiltrating Endomet...mentioning

confidence: 99%

See 2 more Smart Citations

Surgical management of endometriosis to optimize fertility

Hamilton

VanHise

Truong

et al. 2023

Current Opinion in Obstetrics &Amp; Gynecology

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Purpose of reviewSurgery is an integral element of treatment for infertility caused by endometriosis. This review summarizes the purported mechanisms of infertility in endometriosis, as well as the impacts of surgery for endometriosis on fertility, including pregnancy achieved spontaneously and with assisted reproductive technology (ART). Recent findingsEndometriosis' effect on fertility is multifactorial. The sequela of increased inflammation resulting from endometriosis causes alterations in ovarian, tubal, and uterine function. Removing or destroying these lesions reduces inflammation. Surgical treatment of both early-stage endometriosis and deeply infiltrating endometriosis improves spontaneous pregnancy rates and ART pregnancy rates. Conventional or robotic laparoscopy is the preferred surgical approach. SummaryEndometriosis has detrimental effects on fertility, including negative impacts on oocyte, tubal, and endometrial function. Laparoscopic surgery for endometriosis elevates both spontaneous and ART pregnancy rates above those achieved with expectant management alone. The resection or destruction of endometriosis implants reduces inflammation, which likely improves the multifactorial infertility related to endometriosis. This topic is complex and controversial; more research in the form of high-quality randomized control trials is needed.

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Section: Impact Of Surgery On Fertility For Deep Infiltrating Endomet...mentioning

confidence: 78%

Section: Impact Of Surgery On Fertility For Deep Infiltrating Endomet...mentioning

confidence: 99%

Section: Impact Of Surgery On Fertility For Deep Infiltrating Endomet...mentioning

confidence: 99%

See 1 more Smart Citation

Surgical management of endometriosis to optimize fertility

Hamilton

VanHise

Truong

et al. 2023

Current Opinion in Obstetrics &Amp; Gynecology

View full text Add to dashboard Cite

show abstract

“…Esto es especialmente relevante en casos de endometriosis infiltrante profunda con participación del sistema digestivo, donde el beneficio fue aún más notable con un OR de 2.43. Además, la cirugía para endometriosis rectosigmoidea demostró una tasa de embarazo del 60.6% y un 53.9% de nacimientos vivos, respaldando su eficacia (54,55).…”

Section: éXito De Tratamiento Para Abordar La Infertilidad Asociada A...unclassified

“…Además, incluso cuando se consideraron datos de cirugía incompleta, la cirugía previa mostró ventajas. En concordancia un estudio relacionado, Raos et al (55) sus hallazgos también fueron positivos, con tasas de embarazo y nacimientos vivos alentadoras. Esto respalda la idea de que la cirugía específica para tratar la DIE puede mejorar la fertilidad.…”

Section: Cirugía Para La Endometriosis Infiltrante Profunda (Die) Y F...unclassified

Infertilidad asociada a endometriosis. Revisión bibliográfica

Guamán Cango,

Mejia Campoverde

2023

Salud ConCienc.

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Antecedentes: la endometriosis es un trastorno ginecológico común que afecta a hasta el 10% de las mujeres en edad reproductiva, equivale a aproximadamente 170 millones. Además, esta afección está estrechamente relacionada con la infertilidad, afectando al 50% de mujeres que experimentan este problema. Objetivo: describir la infertilidad asociada a la endometriosis Resultados: los factores de riesgo ambientales asociados a la endometriosis, como el consumo de alcohol y la exposición a disruptores endocrinos, han sido ampliamente investigados, mostrando vínculos con la enfermedad debido a sus efectos en los niveles hormonales y los receptores de estrógenos. El consumo de carne roja también se asocia con un mayor riesgo debido a su influencia en los niveles de estrógeno y la inflamación. En cuanto al tratamiento, la cirugía previa a la FIV beneficia a las pacientes con endometriosis infiltrante profunda, mejorando las tasas de embarazo y nacimientos vivos. Las terapias hormonales, antes y después de la cirugía, son efectivas, y la transferencia de embriones congelados mejora las tasas de nacimientos vivos. La Medicina Tradicional China es una opción segura y efectiva para tratar la infertilidad en pacientes con endometriosis, prometiendo un futuro alentador en su manejo.

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