Background
Cardiovascular disease (CVD) hospitalizations declined worldwide during the COVIDâ19 pandemic. It is unclear how shelterâinâplace orders affected acute CVD hospitalizations, illness severity, and outcomes.
Hypothesis
COVIDâ19 pandemic was associated with reduced acute CVD hospitalizations (heart failure [HF], acute coronary syndrome [ACS], and stroke [CVA]), and worse HF illness severity.
Methods
We compared acute CVD hospitalizations at Duke University Health System before and after North Carolina's shelterâinâplace order (January 1âMarch 29 vs. March 30âAugust 31), and used parallel comparison cohorts from 2019. We explored illness severity among admitted HF patients using ADHERE (âhigh riskâ: >2 points) and GWTGâHF (â>10%â: >57 points) inâhospital mortality risk scores, as well as echocardiographyâderived parameters.
Results
Comparing hospitalizations during January 1âMarch 29 (N = 1618) vs. March 30âAugust 31 (N = 2501) in 2020, mean daily CVD hospitalizations decreased (18.2 vs. 16.1 per day, p = .0036), with decreased length of stay (8.4 vs. 7.5âdays, p = .0081) and no change in inâhospital mortality (4.7 vs. 5.3%, p = .41). HF hospitalizations decreased (9.0 vs. 7.7 per day, p = .0019), with higher ADHERE (âhigh riskâ: 2.5 vs. 4.5%; p = .030), but unchanged GWTGâHF (â>10%â: 5.3 vs. 4.6%; p = .45), risk groups. Mean LVEF was lower (39.0 vs. 37.2%, p = .034), with higher mean LV mass (262.4 vs. 276.6âg, p = .014).
Conclusions
CVD hospitalizations, HF illness severity, and echocardiography measures did not change between admission periods in 2019. Evaluating shortâterm data, the COVIDâ19 shelterâinâplace order was associated with reductions in acute CVD hospitalizations, particularly HF, with no significant increase in inâhospital mortality and only minor differences in HF illness severity.