Impact of the digital health application ViViRA on spinal mobility, physical function, quality of life and pain perception in patients with seronegative spondyloarthropathies: a randomized controlled trial

Abstract

Background: Seronegative spondyloarthropathies (SpA) are a group of common rheumatic diseases that often cause limited mobility and lower back pain. Physiotherapy is an integral part of treatment, but access to physiotherapy limits treatment success. Digital health applications (DHAs) enable home-based physiotherapy and could significantly improve access for SpA patients. The aim is to investigate the clinical effects of the DHA ViViRA compared with those of standard physiotherapy. Methods: SpA patients with persistent back pain were enrolled in a randomized controlled trial. The intervention group received ViVira DHA, whereas the control group received standard physiotherapy. Pain (verbal rating scale, PAIN-Detect), quality of life (SF-36) and mobility (BASMI) were assessed at baseline and after 12 weeks as the primary outcomes. Results: Data from 59 participants (71.2% female, mean age 45.2 years) were analyzed. The intervention group showed a significant improvement in mobility (average BASMI score: baseline: 1.12 [range 0.7-1.5]; follow-up: 0.95 [range 0.5-1.4]; p=0.047), whereas the control group showed a significant decrease in mobility (baseline: 1.5 [range 1.1-1.9]; follow-up: 1.8 [range 1.4-2.2]; p=0.002). The intervention group demonstrated significantly lower pain intensity (VRS pain level at week 3.5 ± 2.8) than did the control group (VRS pain level at week 4.5 ± 2) after 12 weeks. Conclusion: Our results highlight the efficacy of DHAs such as ViViRA in the treatment of lower back pain in SpA patients. Compared with the current gold standard, physiotherapy, DHA use results in superior outcomes. However, further larger studies are needed to confirm these promising results. Trial Registration: The study is registered in the German clinical trial registry (DRKS) under the following ID: DRKS00031254