Impact of the dosing of basic drugs on the risk of rehospitalization in patients with chronic heart failure

Ag, Arutyunov; Dragunov, Dmitry; Gp, Arutyunov; Av, Sokolova

doi:10.17116/terarkh201688129-34

Cited by 7 publications

(2 citation statements)

References 9 publications

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“…В российских и зарубежных исследованиях было показано, что самое выраженное неблагоприятное влияние на риск обострений течения заболевания и повторных госпитализаций оказывает факт нерегулярного приема диуретиков . Так, однократный прием мочегонных в неделю даже на фоне оптимальных, оттитрованных доз иАПФ и БАБ приводил к увеличению риска регоспитализации на 33 % [232] . В то же время при изучении 750 амбулаторных карт пациентов с ХСН в рамках пилотного исследования ЭПОХА-Д-ХСН на амбулаторном этапе ведения регистрировалось практически полное отсутствие контроля веса как со стороны пациентов, так и со стороны лечащих врачей .…”

Section: глава 11 немедикаментозное лечение и организация ухода за пациентами с хснunclassified

Russian Heart Failure Society, Russian Society of Cardiology. Russian Scientific Medical Society of Internal Medicine Guidelines for Heart failure: chronic (CHF) and acute decompensated (ADHF). Diagnosis, prevention and treatment

Mareev

Фомин

Агеев

et al. 2018

CARDIO

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Клинические рекомендации ОССН -РКО -РНМОТ . Сердечная недостаточность: хроническая (ХСН) и острая декомпенсированная (ОДСН) . Диагностика, профилактика и лечение Мареев В . Ю . 1 (сопредседатель рабочей группы), Фомин И . В . 2 (сопредседатель рабочей группы), Агеев Ф .

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Section: глава 11 немедикаментозное лечение и организация ухода за пациентами с хснunclassified

Russian Heart Failure Society, Russian Society of Cardiology. Russian Scientific Medical Society of Internal Medicine Guidelines for Heart failure: chronic (CHF) and acute decompensated (ADHF). Diagnosis, prevention and treatment

Mareev

Фомин

Агеев

et al. 2018

CARDIO

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294

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“…Оценка риска повторных госпитализаций пациентов с ХСН важна не только с экономических позиций, но и с учетом увеличения риска смерти с каждой последующей госпитализацией [17,29]. В настоящем исследовании доля повторно госпитализированных больных в течение двух лет наблюдения была ниже в группе специализированного наблюдения и лечения.…”

Section: южно-российский журнал терапевтической практикиunclassified

Rationale of specialized medical care for patients with chronic heart failure in the Russian Federation

Фомин

Vinogradova

2020

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Objectives: to determine the causes of ineffective observation and poor prognosis in patients undergoing ADHF, in real clinical practice and to consider the basics of the formation of specialized medical care for patients with heart failure (HF).Materials and methods: the study was conducted based on the City Center for the treatment of heart failure (center HF), N. Novgorod. The study consistently included 942 patients with heart failure (HF) at the age of 18 years and older who underwent ADHF and received inpatient treatment in center HF between March 4, 2016 and March 3, 2017. Based on the decisions of patients to continue outpatient monitoring in center HF, two groups of patients were distinguished: patients who continued to be monitored in center HF (group I, n = 510) and patients who continued to be monitored in outpatient clinics at the place of residence (group II, n = 432). The assessment of adherence to treatment, overall mortality, survival and re-admission to a depth of two years of observation was carried out. Statistical data processing was performed using Statistica 7.0 for Windows and the software package R.Results: all patients in the study groups had high comorbidity. Group 2 patients turned out to be statistically significantly older, more often had III functional class (FC) HF, lower the baseline test score of 6-minute walk, and higher the baseline clinical assessment scale. After 2 years of follow-up in group II, there was a significant deterioration in adherence to basic therapy of HF compared with group I. According to the results of multifactorial proportional risk Cox models, it was shown that observation of patients in the group 1 is an independent factor increasing the risk of overall mortality by 2.8 times by the end of the second year of observation. Survival after two years of follow-up was: in group I — 89.8 %, and in group II — 70.1 % of patients (OR = 0.3, 95 % CI 0.2 – 0.4; p1/2 < 0.001). After two years of follow-up, the proportion of re-hospitalized patients in group II was greater (78.0 % of patients) versus group 1 (50.6 % of patients, OR = 3.5, 95 % CI 2.6 – 4.6; p1/2 <0.001). The independent risk of re-hospitalization according to multinominal logit regression was 3.4 times higher in group II and 2.4 times for III – IV FC HF. Conclusions: the inclusion of patients with HF in the system of specialized medical care improves adherence to treatment, prognosis of life and reduces the risk of repeated hospitalizations. Patients of an older age and with an initially greater clinical severity refused specialized supervision in center HF.

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Study on the effect and mechanism of the dysfunction of CD4+ T cells in the disease process of chronic cardiac failure

Cai

et al. 2016

Asian Pacific Journal of Tropical Medicine

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Impact of the dosing of basic drugs on the risk of rehospitalization in patients with chronic heart failure

Abstract: The risk of rehospitalization is largely determined by the dosing factor in outpatient settings. Increasing the doses during adjustment reduces the risk of rehospitalization.

Cited by 7 publications

References 9 publications

Russian Heart Failure Society, Russian Society of Cardiology. Russian Scientific Medical Society of Internal Medicine Guidelines for Heart failure: chronic (CHF) and acute decompensated (ADHF). Diagnosis, prevention and treatment

Russian Heart Failure Society, Russian Society of Cardiology. Russian Scientific Medical Society of Internal Medicine Guidelines for Heart failure: chronic (CHF) and acute decompensated (ADHF). Diagnosis, prevention and treatment

Rationale of specialized medical care for patients with chronic heart failure in the Russian Federation

Study on the effect and mechanism of the dysfunction of CD4+ T cells in the disease process of chronic cardiac failure

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