Impact of the environment on the microbiome

Chong-Neto, Herberto José; D’Amato, Gennaro; Filho, Nelson Augusto Rosário

doi:10.1016/j.jped.2021.10.001

Cited by 10 publications

(4 citation statements)

References 53 publications

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“…Several studies have previously confirmed that indoor passive smoking, 16 parental smoking, 25 , 26 , 27 keeping houseplants, 28 petkeeping, 16 and indoor dampness phenomena 29 are closely related to the development of respiratory diseases in children, although this study did not draw the above conclusions. This may be because this study employed a case-control design, and for the case group, subjects were selected strictly according to the physician-diagnosed AR.…”

Section: Discussioncontrasting

confidence: 73%

Parental, gestational, and early-life exposure to indoor environmental hazardous factors on allergic rhinitis among preschool children in Urumqi City: a case-control study

Wang

Shi

et al. 2023

Jornal de Pediatria

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Section: Discussioncontrasting

confidence: 73%

Parental, gestational, and early-life exposure to indoor environmental hazardous factors on allergic rhinitis among preschool children in Urumqi City: a case-control study

Wang

Shi

et al. 2023

Jornal de Pediatria

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“…Many environmental factors have been described as being able to modulate the microbiota composition. Among them, age, diet, or the use of certain medications are the main ones [ 34 , 35 ]. Long-term alterations in the microbiota/mucosal interface can result in systemic translocation of commensal microorganisms, susceptibility to pathogenic invasion, and chronic inflammatory immune responses.…”

Section: Gut Microbiota Alterations In Multiple Sclerosismentioning

confidence: 99%

Microbiota, IgA and Multiple Sclerosis

2022

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Multiple sclerosis (MS) is a neuroinflammatory disease characterized by immune cell infiltration in the central nervous system and destruction of myelin sheaths. Alterations of gut bacteria abundances are present in MS patients. In mouse models of neuroinflammation, depletion of microbiota results in amelioration of symptoms, and gavage with MS patient microbiota exacerbates the disease and inflammation via Th17 cells. On the other hand, depletion of B cells using anti-CD20 is an efficient therapy in MS, and growing evidence shows an important deleterious role of B cells in MS pathology. However, the failure of TACI-Ig treatment in MS highlighted the potential regulatory role of plasma cells. The mechanism was recently demonstrated involving IgA+ plasma cells, specific for gut microbiota and producing IL-10. IgA-coated bacteria in MS patient gut exhibit also modifications. We will focus our review on IgA interactions with gut microbiota and IgA+ B cells in MS. These recent data emphasize new pathways of neuroinflammation regulation in MS.

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“…Recent researches have demonstrated the impact of environmental factors on the host microbiome [ 13 ]. Comparing to outdoor environments, the indoor microbial environments are often overlooked but equally important [ 14 ]. Meanwhile, growing evidence shows that the microbial structure of the perinatal maternal digestive tract is fragile [ 15 , 16 ] and can be modified by several factors including exogenous environmental microorganism colonization [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

Removal of leftover feed shapes environmental microbiota and limits houseflies-mediated dispersion of pathogenic bacteria in sow breeding farms

Li,

Chen,

Chen

et al. 2024

anim microbiome

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Background Intensive swine breeding industry generates a complex environment where several microbial interactions occur and which constitutes a challenge for biosafety. Ad libitum feeding strategies and low levels of management contribute to residual and wasted feed for lactating sows, which provides a source of nutrients and microbial source for houseflies in warm climates. Due to the absence of the all-in/all-out system, the coexistence of sows of two production stages including gestating and lactating sows in the farrowing barn may have potential negative impacts. In this research, we evaluated the effects of lactating sow leftover on the environmental microbiota of the farrowing barn and the contribution of microbial environments to the gestating sow fecal bacterial structure with a 30-day-long treatment of timely removing lactating residual feed. Results Houseflies in the farrowing barn mediate the transmission of microorganisms from lactating sow leftover to multiple regions. Leuconostoc, Weissella, Lactobacillus and Pediococcus from the leftover which can produce exopolysaccharides, are more capable of environmental transmission than pathogenic microorganisms including Staphylococcus and Streptococcus and utilize houseflies to achieve spread in environmental regions of the farrowing barn. Leftover removal treatment blocked the microbial transmission chain mediated by houseflies, downregulated the relative abundance of pathogenic bacteria including Escherichia-Shigella and Streptococcus among houseflies, environmental regions and fecal bacteria of gestating sows in the farrowing barn and effectively attenuate the increment of Weissella and RF39 relative abundance in gestating sow feces due to the presence of lactating sows. Conclusions Lactating sow leftover is a non-negligible microbial contributor of environment in farrowing barn whose transmission is mediated by houseflies. A 30-day-long treatment of removing lactating sow residual feed cause significant changes in the microbial structure of multiple environmental regions within the farrowing barn via altering the microbiota carried by houseflies. Meanwhile, lactating sow leftover affect the fecal microbial structure of gestating sows in the same farrowing barn, while removal of lactating sow leftover alleviates the contribution of microbial transmission.

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Impact of the environment on the microbiome

Cited by 10 publications

References 53 publications

Parental, gestational, and early-life exposure to indoor environmental hazardous factors on allergic rhinitis among preschool children in Urumqi City: a case-control study

Parental, gestational, and early-life exposure to indoor environmental hazardous factors on allergic rhinitis among preschool children in Urumqi City: a case-control study

Microbiota, IgA and Multiple Sclerosis

Removal of leftover feed shapes environmental microbiota and limits houseflies-mediated dispersion of pathogenic bacteria in sow breeding farms

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