Impact of the level of metabolic control on the non-surgical periodontal therapy outcomes in diabetes mellitus type 2 patients: Clinical effects

Mirnic, Jelena; Djuric, M.; Predin, Tanja; Gusic, Ivana; Petrovic, Dan; Anđelković, Aleksandra; Bajkin, Branislav

doi:10.2298/sarh1312738m

Cited by 10 publications

(18 citation statements)

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“…excluded articles). Twelve studies enrolling 491 participants were finally selected (Camargo et al., ; Cirano et al., ; da Cruz et al., ; Dag, Firat, Arikan, Kadiroglu, & Kaplan, ; Dogan et al., ; Kara, Cifcibasi, Karsidag, & Cintan, ; Kardesler, Buduneli, Cetinkalp, & Kinane, ; Mirnic et al., ; Navarro‐Sanchez, Faria‐Almeida, & Bascones‐Martinez, ; Shen, Yin, & Shu, ; Silva‐Boghossian, Orrico, Goncalves, Correa, & Colombo, ; Wei, Chang, Pan, Yu, & Zhao, ) and fifteen data sets were included in the analyses because three studies had groups of patients with DM at different levels of glycaemic control (Dag et al., ; Kardesler et al., ; Mirnic et al., ).…”

Section: Resultsmentioning

confidence: 99%

“…Since the difference in mean baseline PD between the two groups was significantly associated with mean PD reduction after nonsurgical treatment, these data sets were categorized into mean baseline PD difference ≥0 (mean baseline PD in the DMP group is higher than the P group) or <0 (mean baseline PD in the DMP group is lower than the P group). The mean baseline PD difference ≥0 group ap- (Mirnic et al, 2013).…”

Section: Subgroup Analysis and Sensitivity Analysismentioning

confidence: 96%

“…Four out of twelve studies had included less than 30% smokers; whereas the rest of the selected articles either did not include smokers or did not mention in the study. (Kara et al, 2015;Kardesler et al, 2010;Mirnic et al, 2013;Navarro-Sanchez et al, 2007;Wei et al, 2011). (Table 1).…”

Section: Study Characteristicsmentioning

confidence: 99%

“…WDCAL was the lowest while one study,Navarro-Sanchez et al (2007), was omitted (−0.047, CI: [−0.133, 0.040])(Navarro-Sanchez et al, 2007). WDCAL was the highest while the data set ofMirnic et al (2013), a well-controlled DMP group, was omitted (0.014, CI: [−0.07, 0.099])(Mirnic et al, 2013).…”

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confidence: 99%

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Impact of diabetes on clinical periodontal outcomes following non‐surgical periodontal therapy

Hsu

Nair

Angelov

et al. 2019

J Clinic Periodontology

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Aim This systematic review aimed to evaluate the impact of diabetes mellitus on clinical outcomes of non‐surgical periodontal therapy. Materials and Methods Searches were conducted in electronic databases to screen studies published from January 1960 to August 2018. The included studies had at least two groups of patients: chronic periodontitis only (P) or both diabetes and chronic periodontitis (DMP). Outcomes of interest included the difference between the two groups in probing depth (PD) reduction and clinical attachment level (CAL) gain following non‐surgical periodontal therapy. Meta‐regression was conducted to evaluate the correlation between the outcomes of interest and contributing factors. Results A total of 12 studies with a follow‐up period up to 6 months were included. There was no significant difference in PD reduction (p = 0.55) or CAL gain (p = 0.65) between the two groups. A positive association between PD reduction and baseline PD difference (p = 0.03), and a negative association between PD reduction and age (p = 0.04) were found. The level of HbA1c at baseline did not significantly affect the difference in PD reduction (p = 0.39) or CAL gain (p = 0.44) between two groups. Conclusions Recognizing the study's limitations, we conclude that diabetes mellitus (HbA1c ≤ 8.5%) does not appear to significantly affect short‐term clinical periodontal outcomes of non‐surgical periodontal treatment.

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Section: Resultsmentioning

confidence: 99%

Section: Subgroup Analysis and Sensitivity Analysismentioning

confidence: 96%

Section: Study Characteristicsmentioning

confidence: 99%

mentioning

confidence: 99%

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Impact of diabetes on clinical periodontal outcomes following non‐surgical periodontal therapy

Hsu

Nair

Angelov

et al. 2019

J Clinic Periodontology

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“…Secondly, diabetes mellitus can increase the severity of periodontitis [15]–[17] and the severity of the periodontitis is always greater than individuals without diabetes [10], [11]. And periodontitis is considered to be one of the diabetic complications [18], [19].…”

Section: Introductionmentioning

confidence: 99%

The Effect of Periodontal Treatment on Hemoglobin A1c Levels of Diabetic Patients: A Systematic Review and Meta-Analysis

et al. 2014

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BackgroundThere is growing evidence that periodontal treatment may affect glycemic control in diabetic patients. And several systematic reviews have been conducted to assess the effect of periodontal treatment on diabetes outcomes. Researches of this aspect are widely concerned, and several new controlled trials have been published. The aim of this study was to update the account for recent findings.MethodsA literature search (until the end of January 2014) was carried out using various databases with language restriction to English. A randomized controlled trial (RCT) was selected if it investigated periodontal therapy for diabetic subjects compared with a control group received no periodontal treatment for at least 3 months of the follow-up period. The primary outcome was hemoglobin A1c (HbA1c), and secondary outcomes were periodontal parameters included probing pocket depth (PPD) and clinical attachment level (CAL).ResultsTen trials of 1135 patients were included in the analysis. After the follow-up of 3 months, treatment substantially lowered HbA1c compared with no treatment after periodontal therapy (–0.36%, 95%CI, −0.52% to −0.19%, P<0.0001). Clinically substantial and statistically significant reduction of PPD and CAL were found between subjects with and without treatment after periodontal therapy (PPD −0.42 mm, 95%CI: −0.60 to −0.23, P<0.00001; CAL −0.34 mm, 95%CI: −0.52 to −0.16, P = 0.0002). And there is no significant change of the level of HbA1c at the 6-month comparing with no treatment (–0.30%, 95%CI, −0.69% to 0.09%, P = 0.13).ConclusionsPeriodontal treatment leads to the modest reduction in HbA1c along with the improvement of periodontal status in diabetic patients for 3 months, and this result is consistent with previous systematic reviews. And the effect of periodontal treatment on HbA1c cannot be observed at 6-month after treatment.

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The influence of bone mineral density and bisphosphonate therapy on the determinants of oral health and changes on dental panoramic radiographs in postmenopausal women

et al. 2016

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Impact of the level of metabolic control on the non-surgical periodontal therapy outcomes in diabetes mellitus type 2 patients: Clinical effects

Cited by 10 publications

References 0 publications

Impact of diabetes on clinical periodontal outcomes following non‐surgical periodontal therapy

Impact of diabetes on clinical periodontal outcomes following non‐surgical periodontal therapy

The Effect of Periodontal Treatment on Hemoglobin A1c Levels of Diabetic Patients: A Systematic Review and Meta-Analysis

The influence of bone mineral density and bisphosphonate therapy on the determinants of oral health and changes on dental panoramic radiographs in postmenopausal women

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