2024
DOI: 10.3389/fcvm.2024.1323423
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Impact of the MIF -173G/C variant on cardiovascular disease risk: a meta-analysis of 9,047 participants

Hamas Fouda,
Wisam N. Ibrahim,
Zumin Shi
et al.

Abstract: IntroductionMany factors contribute to the risk of cardiovascular disease (CVD), an umbrella term for several different heart diseases, including inflammation. Macrophage migration inhibitory factor (MIF) is an important immune modulator that has been shown to be involved in the pathogenesis of different heart diseases, so understanding pathogenic variants of the MIF gene is important for risk stratification. We therefore conducted a meta-analysis to investigate whether the MIF -173G/C (rs755622) polymorphism … Show more

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