Impact of the <scp>CamAPS FX</scp> hybrid closed‐loop insulin delivery system on sleep traits in older adults with type 1 diabetes

Thabit, Hood; Boughton, Charlotte K; Mubita, Womba; Rubio, Jose; Mader, Julia K.; Narendran, Parth; Evans, Mark L.; Leelarathna, Lalantha; Wilinska, Malgorzata E.; Fullwood, Catherine; Gregory, Alice M.; Hovorka, Roman; Rutter, Martin K

doi:10.1111/dom.14914

Cited by 5 publications

(2 citation statements)

References 24 publications

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“…Studies have also found differences in sleep architecture (length of time in the various stages of sleep) and decreased insulin sensitivity with sleep deprivation, 66–68 but again there are mixed results. Only a few studies have directly examined interactions between sleep and glycaemic outcomes, but there is some evidence that variables such as sleep latency, awakenings, and sleep quality may be related to HbA1c, glycaemic variability and average glucose values 69–71 . Furthermore, sleep quality is connected with mental well‐being.…”

Section: Methodsmentioning

confidence: 99%

“…Only a few studies have directly examined interactions between sleep and glycaemic outcomes, but there is some evidence that variables such as sleep latency, awakenings, and sleep quality may be related to HbA1c, glycaemic variability and average glucose values. [69][70][71] Furthermore, sleep quality is connected with mental well-being. At present, the physiological basis of these interactions is unknown, but may involve hormonal mechanisms, such as cortisol.…”

Section: Sleep Quality and Quantitymentioning

confidence: 99%

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Towards the standardisation of adult person‐reported outcome domains in diabetes research: A Consensus Statement development panel

Barnard‐Kelly,

Marrero,

de Wit

et al. 2024

Diabet Med

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Diabetes is unique among chronic diseases because clinical outcomes are intimately tied to how the person living with diabetes reacts to and implements treatment recommendations. It is further characterised by widespread social stigma, judgement and paternalism. This physical, social and psychological burden collectively influences self‐management behaviours. It is widely recognised that the individual's perspective about the impact of trying to manage the disease and the burden that self‐management confers must be addressed to achieve optimal health outcomes. Standardised, rigorous assessment of mental and behavioural health status, in interaction with physical health outcomes is crucial to aid understanding of person‐reported outcomes (PROs). Whilst tempting to conceptualise PROs as an issue of perceived quality of life (QoL), in fact health‐related QoL is multi‐dimensional and covers indicators of physical or functional health status, psychological and social well‐being. This complexity is illuminated by the large number of person reported outcome measures (PROMs) that have been developed across multiple psychosocial domains. Often measures are used inappropriately or because they have been used in the scientific literature rather than based on methodological or outcome assessment rigour. Given the broad nature of psychosocial functioning/mental health, it is important to broadly define PROs that are evaluated in the context of therapeutic interventions, real‐life and observational studies. This report summarises the central themes and lessons derived in the assessment and use of PROMs amongst adults with diabetes. Effective assessment of PROMs routinely in clinical research is crucial to understanding the true impact of any intervention. Selecting appropriate measures, relevant to the specific factors of PROs important in the research study will provide valuable data alongside physical health data.

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Section: Methodsmentioning

confidence: 99%

Section: Sleep Quality and Quantitymentioning

confidence: 99%

Towards the standardisation of adult person‐reported outcome domains in diabetes research: A Consensus Statement development panel

Barnard‐Kelly,

Marrero,

de Wit

et al. 2024

Diabet Med

Self Cite

View full text Add to dashboard Cite

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Ageing well with diabetes: the role of technology

Maltese,

McAuley,

Trawley

et al. 2024

Diabetologia

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Over the past two decades there has been a substantial rise in the adoption of diabetes therapeutic technology among children, adolescents and younger adults with type 1 diabetes, and its use is now also advocated for older individuals. Older people with diabetes are more prone to experience hypoglycaemia because of numerous predisposing factors and are at higher risk of hypoglycaemic events requiring third-party assistance as well as other adverse sequelae. Hypoglycaemia may also have long-term consequences, including cognitive impairment, frailty and disability. Diabetes in older people is often characterised by marked glucose variability related to age-associated changes such as variable appetite and levels of physical activity, comorbidities and polypharmacotherapy. Preventing hypoglycaemia and mitigating glucose excursions may have considerable positive impacts on physical and cognitive function and general well-being and may even prevent or improve frailty. Technology for older people includes continuous glucose monitoring systems, insulin pumps, automated insulin delivery systems and smart insulin pens. Clinical trials and real-world studies have shown that older people with diabetes benefit from technology in terms of glucose management, reductions in hypoglycaemic events, emergency department attendance and hospital admissions, and improvement in quality of life. However, ageing may bring physical impairments and other challenges that hinder the use of technology. Healthcare professionals should identify older adults with diabetes who may benefit from therapeutic technology and then adopt an individualised approach to education and follow-up for individuals and their caregivers. Future research should explore the impact of diabetes technology on outcomes relevant to older people with diabetes. Graphical Abstract

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Exploring Technology’s Influence on Health Behaviours and Well-being in Type 1 Diabetes: a Review

McClure,

Talbo,

Bonhoure

et al. 2024

Curr Diab Rep

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Impact of the CamAPS FX hybrid closed‐loop insulin delivery system on sleep traits in older adults with type 1 diabetes

Cited by 5 publications

References 24 publications

Towards the standardisation of adult person‐reported outcome domains in diabetes research: A Consensus Statement development panel

Towards the standardisation of adult person‐reported outcome domains in diabetes research: A Consensus Statement development panel

Ageing well with diabetes: the role of technology

Exploring Technology’s Influence on Health Behaviours and Well-being in Type 1 Diabetes: a Review

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