Impact of the volume of blood collected by phlebotomy on transfusion requirements in preterm infants with birth weight of less than 1500 g. A quasi-experimental study

Dik, Pablo H Brener; Galletti, María F; Carrascal, María P; Gregorio, Alejandra De; Pratx, Leandro Burgos; Saldaño, Ana María Gómez; Mariani, Gonzalo

doi:10.5546/aap.2020.eng.109

Cited by 4 publications

(1 citation statement)

References 34 publications

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“…In 2012, Hospital Italiano De Buenos Aires practiced a micro-collection technique for blood samples that significantly reduced blood transfusion requirements. 70 Collection of cord blood samples, clustering blood tests together, and performing tests closer to discharge for greater accuracy can potentially help with these efforts.…”

Section: Future Directionsmentioning

confidence: 99%

Neonatal Anemia

Singh¹,

Chaudhary²,

Jassar³

2022

Newborn

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Neonatal anemia is a public health problem of global concern and has significant associations with many short-and long-term morbidities. Many etiological factors ranging from perinatal physiologic transition, hematological maturation, illnesses, and iatrogenic reasons such as the phlebotomies necessary for laboratory evaluation may be involved, and there is a need for careful clinical decisions. In premature infants, the management of anemia also has to factor in the unique hematological transition seen during development, co-morbidities associated with preterm birth, the severity of illness severity, and all the iatrogenic factors. Untreated severe anemia is known to negatively impact long-term growth and neurodevelopment outcomes, making early diagnosis and treatment imperative. Additionally, there is a lack of consensus about the threshold and timing of packed red blood cell transfusions, and we need further consideration in view of various associated complications. Therefore, clinicians need to focus on preventable causes of anemia such as nutritional deficiencies, chronic illness, and excessive phlebotomy losses. In this article, we attempt to summarize the pathophysiology, etiologies, clinical management, and the opportunities in research in the field of neonatal anemia.

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Section: Future Directionsmentioning

confidence: 99%

Neonatal Anemia

Singh¹,

Chaudhary²,

Jassar³

2022

Newborn

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Analysis of Influencing Factors on the Number of Red Blood Cell Transfusions in NICU Neonates

赵¹

2022

ACM

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The Efficacy of Erythrocyte Transfusion in Very Low Birth Weight Infants with Premature Anemia

YAZICI

Bilgin²,

ÖZCAN>³

et al. 2023

Türkiye Çocuk Hast Derg

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Objective: This study aimed to determine the clinical efficacy of erythrocyte transfusion (ET) in premature infants. Material and Methods: Very low birth weight (VLBW) infants with gestational age (GA) < 32 weeks and/or birth weight (BW) <1500 g and hospitalized in neonatal intensive care unit (NICU) between 2012-2018 were retrospectively evaluated. ET was performed according to Ohls 2007 and Turkish Neonatalogy Society Blood Products Transfusion Guidelines. Results: 72 infants included in this study. Mean BW was 1325 g (680-2290 g), GA was 30 weeks (25-32), median postnatal age was 36.7±26.9 days (8-129), number of ET during hospitalization was 2±1.2 (1-6). There were no significant changes in mean heart rates (p=0.183) and median respiratory rates before and after ET (p=0.123). Weight gain (16 g/day-11 g/day) was statistically similar before and after ET (p=0.861). A significant decrease in apnea, non-invasive ventilation (NIV) and caffeine therapy requirements after ET was determined (p<0.001, p=0.016 and p=0.016). Serum lactate (2.9-1.5) levels were decreased by ET (p=0.017). Conclusion: Premature infants should closely follow-up for anemia and related symptoms during NICU stay. ET may help to decrease frequency of apnea of prematurity, requirements of caffeine therapy and NIV. ET improves tissue oxygenation in VLBW infants with anemia. Decision of ET should be made according to severity of symptoms, and should be performed according to international, national or local transfusion guidelines.

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Impact of the volume of blood collected by phlebotomy on transfusion requirements in preterm infants with birth weight of less than 1500 g. A quasi-experimental study

Cited by 4 publications

References 34 publications

Neonatal Anemia

Neonatal Anemia

Analysis of Influencing Factors on the Number of Red Blood Cell Transfusions in NICU Neonates

The Efficacy of Erythrocyte Transfusion in Very Low Birth Weight Infants with Premature Anemia

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