Impact of Time Interval Between Glenn and Fontan Procedures on Fontan Operative and Long-Term Follow-up Results

Fan, Guohui; Xing, Yunchao; Zhao, Wei; Zhang, Liang; Fan, Fan; Jiang, Xianchao; Ma, Zhiling; Yan, Jun; Li, Shoujun; Wang, Qiang

doi:10.1007/s00246-018-2049-7

Cited by 2 publications

(4 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our study, the mean BCPS-Fontan duration was significantly shorter in patients with a Fontan completion at ≤ 6 years compared to > 6 years (2 years vs 5 years, p < 0.001). This is consistent with the study by Yi et al [ 13 ].…”

Section: Discussionsupporting

confidence: 94%

“…Yi et al investigated the mortality and morbidity based on the duration between BCPS and Fontan completion > 3.7 years and < 3.7 years. [ 13 ] They found that group with longer duration between BCPS and Fontan (> 3.7 years) had an older mean age of Fontan completion (8.24 ± 3.82 years) compared to group with shorter duration of BCPS and Fontan (< 3.7 years) [ 13 ]. However, no significant difference in mortality and morbidity was found between both groups [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

“…[ 13 ] They found that group with longer duration between BCPS and Fontan (> 3.7 years) had an older mean age of Fontan completion (8.24 ± 3.82 years) compared to group with shorter duration of BCPS and Fontan (< 3.7 years) [ 13 ]. However, no significant difference in mortality and morbidity was found between both groups [ 13 ]. In our study, the mean BCPS-Fontan duration was significantly shorter in patients with a Fontan completion at ≤ 6 years compared to > 6 years (2 years vs 5 years, p < 0.001).…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Impact of older age at Fontan completion on mid-term survival

et al. 2022

View full text Add to dashboard Cite

Background The optimum age of Fontan completion remains unknown. Currently, the majority of centers worldwide are performing Fontan completion at 2–4 years of age. In Indonesia, lack of awareness and limited resources probably explain why patients seek treatment at advanced stage. This study aimed to evaluate the impact of older age at Fontan completion on mid-term survival. Results A single-center retrospective cohort study was performed on 261 patients who underwent Fontan completion between 2008 and 2019 and survived to discharge. The patients were followed up until April 2020, with a median follow-up period of 3 years (range 0–12 years). The median age was 5 years (range 2–24 years). The survival rates of patients with the age at operation ≤ 6 years and > 6 years were 92.1% and 82.8%, respectively. A subgroup analysis showed that the survival rates for age < 4 years, 4–6 years (reference age), 6–8 years, 8–10 years, 10–18 years, and > 18 years were 85.7%, 94.8%, 85.4%, 78.8%, 85.7%, and 66.7%, respectively. Age at Fontan completion of > 6 years (HR 3.84; p = 0.020) was associated with a lower 12-year survival rate. The age at operation of 8–10 years (HR 6.79; p = 0.022) and > 18 years (HR 15.30; p = 0.006) had the worst survival rates. Conclusions An older age at Fontan completion (> 6 years) significantly reduced mid-term survival rate. The age at Fontan of 8–10 years and > 18 years had higher risk of mid-term death than age of 4–6 years.

show abstract

Section: Discussionsupporting

confidence: 94%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Impact of older age at Fontan completion on mid-term survival

et al. 2022

View full text Add to dashboard Cite

show abstract

“…However, we found that doing the operation at older age was not significantly associated with frequency of complications in our post Glenn and Fontan patients (p=0.793, p=0.079 respectively). Our results were comparable to others who recommended postponing Fontan to a feasible extent (8,9). A previous study concluded that Glenn operation was enough as the outcome is reasonable with few late complications (7).…”

Section: Discussionsupporting

confidence: 87%

Children Surviving Post-Univentricular Repair: Single Center Experience

Ibrahim

Mostafa²,

Hanna³

et al. 2022

Pediatric Sciences Journal

View full text Add to dashboard Cite

Background: The children population who underwent single ventricle repair is growing in number with longer follow up periods and increased frequency of complications. Aim of work: To evaluate the outcome and complications post Glenn and Fontan single ventricle repair in children. Material and Methods: A retrospective study of data within files of all surviving patients post univentricular surgical repair, who were following up at Post Cardiac Interventions Clinic in Cairo University Children Hospital from October 2007 until October 2020.Results: The files of 113 patients were enrolled in the study, 93 (82.3%) of them were post Glenn operation. Their mean± SD age at the time of the operation was 1.4± 0.9years, and mean follow up duration of 8.3 ±3 years. The study included 20 (17.7%) patients post Fontan operation, with a mean age at the time of the operation of 7.82± 1.63years, and mean follow up duration of 4.75 ±0.08 years. They were 77 (68.15%) males, and 36(31.85%) females. Complications post Glenn operation were heart failure in 34(36.5%) patients, pericardial and pleural effusion in 4 (4.3%) and hypoalbuminemia in 2 (2.15%). Complications post Fontan were heart failure in 4 (20%) patients, arrhythmia in 2 (10%), and protein losing enteropathy in 2 (10%). Frequency of complications was not related to the age at the time of the Glenn and Fontan operation (p =0.793) and (p=0.079) respectively. Conclusion: Performing Glenn and Fontan at older age was not related to the frequency of complications in our patients. Heart failure was the most common complication post Glenn and Fontan operations.

show abstract

Impact of Time Interval Between Glenn and Fontan Procedures on Fontan Operative and Long-Term Follow-up Results

Cited by 2 publications

References 24 publications

Impact of older age at Fontan completion on mid-term survival

Impact of older age at Fontan completion on mid-term survival

Children Surviving Post-Univentricular Repair: Single Center Experience

Contact Info

Product

Resources

About