Impact of tobacco and/or nicotine products on health and functioning: a scoping review and findings from the preparatory phase of the development of a new self-report measure

Abstract

Background Measuring self-reported experience of health and functioning is important for understanding the changes in the health status of individuals switching from cigarettes to less harmful tobacco and/or nicotine products (TNP) or reduced-risk products (RRP) and for supporting tobacco harm reduction strategies. Methods This paper presents insights from three research activities from the preparatory phase of the development of a new self-report health and functioning measure. A scoping literature review was conducted to identify the positive and negative impact of TNP use on health and functioning. Focus groups (n = 29) on risk perception and individual interviews (n = 40) on perceived dependence in people who use TNPs were reanalyzed in the context of health and functioning, and expert opinion was gathered from five key opinion leaders and five technical consultants. Results Triangulating the findings of the review of 97 articles, qualitative input from people who use TNPs, and expert feedback helped generate a preliminary conceptual framework including health and functioning and conceptually-related domains impacted by TNP use. Domains related to the future health and functioning measurement model include physical health signs and symptoms, general physical appearance, functioning (physical, sexual, cognitive, emotional, and social), and general health perceptions. Conclusions This preliminary conceptual framework can inform future research on development and validation of new measures for assessment of overall health and functioning impact of TNPs from the consumers’ perspective.

Nicotine Exerts Cytotoxic Effects in a Panel of Healthy Cell Lines and Strong Irritating Potential on Blood Vessels

“…Transdermal nicotine patches and smoking’s toxic effects may adversely affect keratinocytes. Nicotine is metabolized primarily by hepatocytes, which is why tobacco use leads to various toxic changes at this level [ 20 ]. Therefore, the current study was designed to assess the effects of nicotine on these cells at the cellular level.…”

Effect of Animated Video Media on Smoking Behavior Students in Junior High School Muhammadiyah 1 Purbolinggo Kabupaten Lampung Timur

“…Berdasarkan hasil penelitian setelah diberikan intervensi menggunakan media video animasi dan kuesioner, hasil penelitian menunjukan adanya perubahan perilaku Kesehatan (Dai et al, 2022); (Flor et al, 2024); (Afolalu et al, 2021); (West, 2017), hal tersebut di tunjukan dengan perbedaan rata-rata jumlah batang rokok yang dihisap siswa sebelum di intervensi dan sesudah di intervensi, selisih rata-rata perbedaan tersebut menunjukan hasil penurunan jumlah batang rokok yang dihisap oleh siswa di SMP Muhammadiyah 1 Purbolinggo. Media video animasi dapat dijadikan sebagai salah satu media yang cukup efektif dalan memberikan edukasi promosi kesehatan tentang bahaya merokok, khususnya kepada siswa SMP Muhammadiyah 1 Purbolinggo Lampung Timur.…”

Smokeless tobacco use and public health nutrition: a global systematic review

“…In generating the framework, a panel of experts panel considered themes and concepts identified under each of the categories from the evidence systematic review, post which, the authors structured and reorganised concepts under main health, functioning and conceptually related domains. This framework provided the basis and insights to comprehend the impact of SLT on health and functioning and conceptually related domains (16) .…”