Impact of transcatheter aortic valve implantation on coexistent mitral regurgitation parameters

Abstract

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Association between calcification of mitro-aortic continuity and mitral regurgitation in patients undergoing transcatheter aortic valve replacement

“…Apart from reduced retrograde transmitral gradient, improvement of MR in patients with lower EF (also within normal limits) may be partially explained by the removal of afterload mismatch following TAVI [32], as acute improvement in MR reported following TAVR was related to immediate post-procedural changes in left ventricular hemodynamics and improved mitral leaflet tethering, resulting from reduced afterload [33]. In our patients, as in the other series, MR worsened following TAVI only in a minority of patients [34][35][36][37].…”

Neutrophil-to-lymphocyte ratio as a predictor of inflammatory response in patients with acute kidney injury after transcatheter aortic valve implantation

“…The median (Q1-Q3) left ventricular ejection fraction (LVEF) was 60% (47.25-60%) and 55% (45-60%) (p = 0.248) in patients without persistent NLR and with persistent NLR, respectively. Similarly, echocardiographic parameters after TAVI did not differ significantly between both subgroups: median (Q1-Q3) MPG values were 8 (6.025-9.975) mm Hg and 9 (7-11.25) mm Hg (p = 0.076), median (Q1-Q3) PPG values were 16.9 (12)(13)(14)(15)(16)(17)(18)(19)(20) mm Hg and 18 (13.1-22.75) mm Hg (p = 0.069), while median (Q1-Q3) EF values were 60% (50-60%) and 55% (50-60%) (p = 0.112), in patients without persistent NLR and with persistent NLR, respectively. Likewise, paravalvular leak (PVL) presence did not show statistical significance (p = 0.359).…”

“…Clinical profile evaluation, echocardiography and computed tomography (CT) examination analyses play fundamental roles, enabling a precise diagnosis as well as the choice of approach and the device type which will more likely achieve the best result. [16][17][18][19][20] Several cardiac and cardiosurgical scores, including the European System for Cardiac Operative Risk Evaluation II (EuroSCORE II), Society of Thoracic Surgeons (STS) score and Intermountain Risk Score, [21][22][23] have been used to determine the mortality risk. Simple laboratory analysis, with C-reactive protein (CRP), 24,25 leucocytes 25 as well as NLR evaluation, 11 may facilitate prediction of clinical outcomes.…”

Balloon aortic valvuloplasty for severe aortic stenosis may reduce mitral regurgitation in mid-term follow-up

“…There is no doubt that TAVR is a valuable treatment option reflected in current ESC guidelines on valvular heart disease [9]. There are numerous data on the beneficial role of TAVR and many papers have shown a significant MR reduction immediately after or during follow-up after TAVR [26][27][28][29][30][31]. Similar results were reported for patients with low-flow and low gra-dient AS [32].…”