Impact of trypanosomosis on food security in Nigeria: A review

Fajinmi, A O; Kalgo, A M; Wyorkson, M A; Yohanna, JA; Faleke, O. O.

doi:10.4314/apra.v3i3.36390

Cited by 2 publications

(2 citation statements)

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“…World health organization (WHO) has described trypanosomosis as a serious disease lacking effective control measures, and all mammalian hosts are susceptible to the infection (Cattand et al, 2005). The disease is characterized by parasitaemia, fever, anaemia, loss of condition and reduced productivity (Abenga et al, 2002;Fajinmi et al, 2007). Over past decades, prevention and control of animal trypanosomosis have relied mainly on chemotherapy and chemoprophylaxis, together with vector control measures.…”

Section: Introductionmentioning

confidence: 99%

The effect of resveratrol supplementation on haematological parameters and trypanocidal efficacy of diminazene aceturate in dogs

Ukwueze¹,

Akpa²,

Odo³

et al. 2023

Sokoto J. Vet. Sc.

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Trypanosomosis is a debilitating, fatal disease of man and animals often associated with anaemia. The trypanocides currently used in the management of the disease are far from giving desired results. This study investigated changes in haematological indices and the treatment outcome of diminazene aceturate (DA) against Trypanosoma brucei in dogs supplemented with resveratrol. A total of twenty (20) male Nigerian local breed of dogs (NBD) aged 6 to 12 months were used for the study. The dogs were randomly assigned into five groups (I-V) of four dogs per group. Group I was uninfected and unsupplemented; group II, was infected, untreated, and unsupplemented; group III, infected unsupplemented, treated with DA, group IV was infected and supplemented but untreated with DA, and group V was infected and supplemented DA-treated. The mean pre-patent period of Trypanosoma infection was 5.75±0.96 and 9.00±0.82 days for the infected unsupplemented and the infected resveratrol-supplemented groups, respectively. There was a complete parasite clearance from peripheral blood within 24-48 hours following treatment with DA on day 10 post-treatment (PT) in the supplemented and 24-72 hours in the unsupplemented treated groups. The supplemented treated did not show any relapse of infection, whereas the un-supplemented, DA-treated showed relapse on day 25 PT. It was concluded that resveratrol supplementation enhanced the efficacy of diminazene aceturate with no risk of relapse, minimized the effects of the parasite in the animals, and increased survival time.

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Section: Introductionmentioning

confidence: 99%

The effect of resveratrol supplementation on haematological parameters and trypanocidal efficacy of diminazene aceturate in dogs

Ukwueze¹,

Akpa²,

Odo³

et al. 2023

Sokoto J. Vet. Sc.

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“…It is ranked among the most important genera of hemoparasites of veterinary importance affecting cattle ( Bakre et al ., 2020 ). The disease is characterized by fever, anemia, reduced productivity, and frequently high mortality, which among the other factors limit the development of rural areas in tropical Africa ( Abenga et al ., 2002 ; Fajinmi et al ., 2007 ). As of 2011, the annual financial burden of animal trypanosomosis in Nigeria was estimated to be above 22 million dollars ( Fadiga et al ., 2013 ).…”

Section: Introductionmentioning

confidence: 99%

Comparative performance evaluation of blood film microscopy for the diagnosis of bovine trypanosomosis by some laboratories in North-central Nigeria

Akinbobola¹,

Okaiyeto²,

Sackey³

et al. 2023

Open Vet J

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Background: Due to its affordability in disease affected communities and suitability for field application, microscopy has historically been considered the gold standard for field diagnosis of trypanosomosis in rural settings. Aim: This works aims to compare the performance of microscopists on bovine trypanosome microscopy by organizing the first comparative assessment on a correct reading of slides by laboratory professionals using the read slide results and a structured interviewer administered questionnaire in North-central Nigeria. Methods: Ten (10) Participants were addressed, as they were sent a panel of two slides (Slide 1: No Trypanosome present; Slide 2: Trypanosome present) and a questionnaire. Results: All participants greater than 41 years old reported correctly the presence and absence of parasite on slides. Only 3/8 of microscopist from Routine diagnostic laboratory reported correctly the presence of the parasite. Conclusion: Our study confirmed errors in reading slides. Therefore, training of microscopist besides a nationwide quality assessment is recommended.

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Impact of trypanosomosis on food security in Nigeria: A review

Cited by 2 publications

References 0 publications

The effect of resveratrol supplementation on haematological parameters and trypanocidal efficacy of diminazene aceturate in dogs

The effect of resveratrol supplementation on haematological parameters and trypanocidal efficacy of diminazene aceturate in dogs

Comparative performance evaluation of blood film microscopy for the diagnosis of bovine trypanosomosis by some laboratories in North-central Nigeria

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