Impact of Vena Cava Filters on In-hospital Case Fatality Rate from Pulmonary Embolism

Stein, Paul D.; Matta, Fadi; Keyes, Daniel C.; Willyerd, Gary

doi:10.1016/j.amjmed.2011.05.025

Cited by 170 publications

(77 citation statements)

References 32 publications

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“…1 Cardiovascular risk factors such as hypertension (HT), diabetes mellitus (DM), hypertriglyceridemia, low high-density lipoprotein (HDL) cholesterol levels, and obesity have been shown to be associated with an increased risk of VTE. 2 Besides, pulmonary embolism (PE) risk is higher in patients with cardiovascular diseases such as myocardial infarction (MI) and heart failure (HF), 3,4 and patients with VTE have an increased risk of MI and stroke.…”

Section: Introductionmentioning

confidence: 99%

Higher CHA₂DS₂-VASc Score Is Associated With Increased Mortality in Acute Pulmonary Embolism

Onuk

Karataş

İpek

et al. 2016

Clin Appl Thromb Hemost

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Background: CHA 2 DS 2 -VASc score has been validated in risk prediction for stroke and thromboembolism in patients with atrial fibrillation (AF). Association of CHA 2 DS 2 -VASc score with higher risk of venous thromboembolism and pulmonary embolism (PE) has also been shown. In this study, we investigated the long-term prognostic value of CHA 2 DS 2 -VASc score in patients with acute pulmonary embolism (APE). Methods: Consecutive patients with APE presenting to our emergency department were retrospectively recruited. Patients with AF and who died secondary to causes other than PE were excluded from the study. The CHA 2 DS 2 -VASc score and pulmonary embolism severity index (PESI) were calculated. Results: Two hundred seventy seven participants were included in the study. The mortality rate was 18.7%. Twenty-two cases died within 30 days, and 30 cases died during the follow-up period (median: 13 months). The mean CHA 2 DS 2 -VASc score was significantly higher in dead patients compared to survivors (3.61 + 1.35 vs 1.95 + 1.52, P < .01). In multivariate regression analysis, systolic pulmonary artery pressure (hazard ratio [HR]: 1.03, 95% confidence interval [CI]: 1.01-1.06, P ¼ .02), PESI score (HR: 1.010, 95% CI: 1.004-1.017, P < .01), and CHA 2 DS 2 -VASc score (HR: 1.67, 95% CI: 1.19-2.16, P < .01) were found to be independently correlated with mortality. The patients whose CHA 2 DS 2 -VASc score was between 1 and 3 had 5.67 times and patients whose CHA 2 DS 2 -VASc score was 4 had 16.8 times higher risk of mortality compared to patients with CHA 2 DS 2 -VASc score ¼ 0. Conclusion: Patients with higher CHA 2 DS 2 -VASc scores had higher rates of mortality after APE.

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Section: Introductionmentioning

confidence: 99%

Higher CHA₂DS₂-VASc Score Is Associated With Increased Mortality in Acute Pulmonary Embolism

Onuk

Karataş

İpek

et al. 2016

Clin Appl Thromb Hemost

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“…15,16,17 Venous filters are usually placed in the infrarenal portion of the IVC.Venous filters are indicated in patients with acute PE who have absolute contraindications to anticoagulant drugs, and in patients with objectively confirmed recurrent PE despite adequate anticoagulation treatment. Observational studies suggest that insertion of a venous filter might reduce PE-related mortality rates in the acute phase, 18,19 benefit possibly coming at the cost of an increased risk of recurrence of VTE. 19 As in our case the old lady presented to us in syncope with mild dyspnoea and tachypnoea but without clinical features such as chest pain, palpitation and haemoptysis.…”

Section: Discussionmentioning

confidence: 99%

Pulmonary Embolism presenting as Syncope

Mall

Sha-ning

2015

Nepalese Heart J.

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“…DVT ve PE tedavisinde vena kava filtrelerinin de sınırlı fakat önemli bir yeri vardır. Yapılan tek randomize olmayan çalışmada rutin vena kava filtresi uygulamasının VTE nüksü ve total mortalite oranlarını değiştirmediğini, DVT'de artma ancak PE'de azalma sağladığını, PTS sıklığını etkilemediğini bulunmuştur 18,19 . Bu cihazlarla ilgili en önemli problem filtre etrafında tromboz gelişimidir.…”

Section: Kateter Yollu Girişimsel Tedavilerunclassified

Derin Ven Trombozunda Güncel Tedaviler

Tekin¹

2015

Arşiv Kaynak Tarama Dergisi

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Venous thromboembolism is a disease spectrum that encompasses all pathologic thrombotic conditions observed in human venous system. It is most frequently seen in lower extremity deep veins where it is named as deep vein thrombosis. However, it might also be detected in upper extremity, pelvic and other venous systems of the body. Pulmonary embolism is the life-threatening component of venous thromboembolism. Rapid diagnosis and optimal treatment of are vital for decreasing patient mortality, morbidity, and the incidence of recurrent events. Initial treatment with unfractionated heparin, low-molecular weight heparin, or fondaparinux overlapped with warfarin is the currently approved treatment in most cases. Warfarin monotherapy is then continued for a time period which depends on the specific conditon of patients. These current treatment guidelines were published before the approval of new oral anticoagulants. The advantages of new oral anticoagulants are the ease of use, reduced monitoring requirements, and probably lower bleeding risk than warfarin therapy. This review addresses the current treatment of venous thromboembolism, with a particular emphasis on new oral anticoagulants. Key words: Deep vein thrombosis, Dabigatran, Apixaban, Rivoraxaban, Warfarin ÖZET Venöz tromboembolizm, insan venöz dolaşımında görülen tüm patolojik trombozları kapsayan hastalık durumudur. En sık olarak alt ekstremite derin venlerinde (derin ven trombozu) görülür. Bununla birlikte, üst ekstremite, pelvis ve diğer vücut venlerinde de görülebilmektedir. Venöz tromboembolizmin yaşamı tehdit eden parçası ise pulmoner embolidir. Hasta mortalitesinin, morbiditesinin ve tekrarlayan olayların azaltılması için hızlı tanı ve optimum tedavi yaşamsaldır. Çoğu hastaya başlangıçta warfarine ek olarak fraksiyone olmayan heparin, düşük molekül ağırlıklı heparin

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Impact of Vena Cava Filters on In-hospital Case Fatality Rate from Pulmonary Embolism

Cited by 170 publications

References 32 publications

Higher CHA₂DS₂-VASc Score Is Associated With Increased Mortality in Acute Pulmonary Embolism

Higher CHA₂DS₂-VASc Score Is Associated With Increased Mortality in Acute Pulmonary Embolism

Pulmonary Embolism presenting as Syncope

Derin Ven Trombozunda Güncel Tedaviler

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Impact of Vena Cava Filters on In-hospital Case Fatality Rate from Pulmonary Embolism

Cited by 170 publications

References 32 publications

Higher CHA2DS2-VASc Score Is Associated With Increased Mortality in Acute Pulmonary Embolism

Higher CHA2DS2-VASc Score Is Associated With Increased Mortality in Acute Pulmonary Embolism

Pulmonary Embolism presenting as Syncope

Derin Ven Trombozunda Güncel Tedaviler

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Higher CHA₂DS₂-VASc Score Is Associated With Increased Mortality in Acute Pulmonary Embolism

Higher CHA₂DS₂-VASc Score Is Associated With Increased Mortality in Acute Pulmonary Embolism