Impact of vision and hearing impairments on risk of cardiovascular outcomes and mortality in patients with type 2 diabetes: A nationwide cohort study

Jung, Younhea; Han, Kyungdo; Lee, Ji Min; Park, Hye Yeon; Moon, Jooho

doi:10.1111/jdi.13689

Cited by 6 publications

(9 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among the studies which used audiometry, 5 studies used a pure‐tone audiometric threshold of 25 dB or greater to define HL in accordance with the World Health Organization definition, 41 while the remaining 2 used a threshold of 40 dB or greater to define HL. Five studies used air conduction audiometry, 32,34,36‐38 one used both air and bone conduction audiometry, 35 while the last study did not specify the specific type of audiometry assessment used 33 …”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Association Between Hearing Loss and Cardiovascular Disease: A Meta‐analysis

Tan,

Koh,

Tan

et al. 2023

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

ObjectiveHearing loss (HL) has been postulated to be linked to cardiovascular diseases (CVDs) via vascular mechanisms, but epidemiological associations remain unclear. The study aims to clarify the association between HL and stroke, coronary artery disease (CAD), and any CVD.Data SourcesPubMed, Embase, and SCOPUS from inception until April 27, 2022.Review MethodsThree blinded reviewers selected observational studies reporting stroke, CAD, and any CVD in patients with HL, compared to individuals without HL. We extracted data, evaluated study bias using the Newcastle‐Ottawa scale, following Preferred Reporting Items for Systematic Reviews and Meta‐analyses guidelines and a PROSPERO‐registered protocol (CRD42022348648). We used random‐effects inverse variance meta‐analyses to pool the odds ratios (ORs) for the association of HL with stroke, CAD, and any CVD.ResultsWe included 4 cohort studies (N = 940,771) and 6 cross‐sectional studies (N = 680,349). Stroke, CAD, and any CVD were all strongly associated with HL. The overall pooled OR of the association between HL and stroke was 1.26 (95% confidence interval [CI] = 1.16‐1.37, I2 = 78%), and was 1.33 (95% CI = 1.12‐1.58) and 1.29 (95% CI = 1.14‐1.45) for low‐ and high‐frequency HL, respectively. Minimal publication bias was observed, with minimal change to pooled effect size following trim and fill. Similarly, the pooled OR of the association between HL and CAD was 1.36 (95% CI = 1.13‐1.64, I2 = 96%), while that between HL and any CVD was 1.38 (95% CI = 1.07‐1.77, I2 = 99%).ConclusionOur findings suggest that HL and CVD are closely related. Physicians treating patients with HL should be cognizant of this association and view HL in the broader context of general health and aging.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Five studies used air conduction audiometry, 32,34,[36][37][38] one used both air and bone conduction audiometry, 35 while the last study did not specify the specific type of audiometry assessment used. 33…”

Section: Study Characteristicsmentioning

confidence: 99%

Association Between Hearing Loss and Cardiovascular Disease: A Meta‐analysis

Tan,

Koh,

Tan

et al. 2023

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

show abstract

“…Surprisingly, this reduced CV risk score occurs mostly in patients that present worse baseline VA scores. Since impaired vision is associated with increased frailty and increased risk of death due to CVDs, 4–11 we hypothesize that this improved CV risk score in these patients is due to improved vision. However, we do not know why this occurs.…”

Section: Discussionmentioning

confidence: 99%

“…2,3 Moreover, vision loss correlates with increased incidence of adverse conditions such as depression 4 falls and fractures. 5 In addition, vision impairment associates with higher prevalence of underlying chronic diseases such as cardiovascular diseases (CVDs), poorer overall survival and increased risk of mortality [6][7][8][9][10][11] .…”

Section: Introductionmentioning

confidence: 99%

Reduced cardiovascular risk score following bilateral cataract phacoemulsification surgery: A retrospective observational cohort study

Matias

Alves-Peixoto

Miranda

et al. 2023

European Journal of Ophthalmology

View full text Add to dashboard Cite

Objective To assess the cardiovascular risk (CV risk) change following bilateral phacoemulsification cataract surgery. Methods We performed a retrospective observation cohort study on 112 selected patients who underwent uncomplicated bilateral cataract surgery at Centro Hospitalar de Entre o Douro e Vouga (CHEDV) between 2018 and 2019. This patient cohort was further subdivided in 2 different groups: Good VA – no to mild visual impairment, ≤0.48 LogMAR; Bad VA – moderate to severe visual impairment, >0.48 LogMAR. We compared the changes in the CV risk score components in our patient cohort and between subgroups Good VA and Bad VA, before and after surgery, using paired t-test or Wilcoxon rank-sum test, and repeated measures ANOVA with Tukey post-hoc tests, respectively. Visual Acuity (VA) before and after surgery was correlated with the patients’ CV risk score. At last, linear regression models were built to explain changes in CV risk variables considering the change in VA. Results Cataract surgery resulted in improved VA. Notably, following surgery our patient cohort showed reduced low-density lipoprotein (LDL) levels after surgery, from 111.17±36.26 mg/dL to 104.22±37.53 mg/dL, and reduced systolic arterial pressure (SAP), from 139.1±15.0 mmHg to 133.7±12.0 mmHg. Ultimately, this translated to an improved CV risk score within 6 months of cataract surgery, from 17.39±11.44% to 16.51±11.27%. Of note, these improvements were mostly present in the Bad VA group of patients, where baseline VA and incidence of dyslipidemia were worse. Conclusion Our results suggest that phacoemulsification cataract surgery may be an important tool in addressing CV risk.

show abstract

“…Furthermore, impaired vision is associated with increased prevalence of other comorbidities, including depression 4 , falls and fractures 5 . Of note, vision loss associates with higher prevalence of underlying chronic diseases such as cardiovascular diseases (CVDs) and decreased life-expectance [6][7][8][9][10][11] .…”

Section: Introductionmentioning

confidence: 99%

Improved glycaemic control and cardiovascular risk in patients with DM-II following Cataract Phacoemulsification surgery

Matias

Alves-Peixoto

Miranda

et al. 2022

Preprint

View full text Add to dashboard Cite

Objective: Assess the glycemic control and cardiovascular risk (CV risk) change in Diabetes-Mellitus type II (DM-II patients) undergoing uncomplicated bilateral cataract phacoemulsification surgery. Design: Retrospective study. Participants: We selected 28 patients who underwent uncomplicated bilateral cataract surgery at Centro Hospitalar de Entre o Douro e Vouga between January 2018 and December 2019. Inclusion criteria: inexistence of other known ophthalmological pathology, the availability of their records of comorbidities, lipid profile, blood pressure, glycated hemoglobin (HbA1c) and body max index (BMI) prior to and in the 6 months following surgery. Methods: We assessed our patient cohort for changes in HbA1c, lipid profile, BMI and blood pressure before and after surgery. We further subdivided our patient cohort in 2 different groups: group 1 – no to mild visual impairment, ≤0.48 LogMAR; group 2 – moderate to severe visual impairment, >0.48 LogMAR, and assessed for the same variables at the mentioned timepoints. Comparisons were done using paired samples Student’s T-test or Wilcoxon rank, and repeated measures ANOVA with Tukey Post-Hoc tests, respectively. Results: Following cataract surgery and subsequent improved visual acuity (VA), our patient cohort showed decreased HbA1c, lower arterial blood pressure and decreased BMI, with an improved CV risk score within 6 months of cataract surgery. These improvements where more evident in the patients with worse baseline VA. Conclusions: Phacoemulsification cataract surgery should be considered in patients with visual impairment, particularly in those that benefit from improved glycemic control and whom need to reduced their cardiovascular risk, such as DM-II patients.

show abstract

Impact of vision and hearing impairments on risk of cardiovascular outcomes and mortality in patients with type 2 diabetes: A nationwide cohort study

Cited by 6 publications

References 33 publications

Association Between Hearing Loss and Cardiovascular Disease: A Meta‐analysis

Association Between Hearing Loss and Cardiovascular Disease: A Meta‐analysis

Reduced cardiovascular risk score following bilateral cataract phacoemulsification surgery: A retrospective observational cohort study

Improved glycaemic control and cardiovascular risk in patients with DM-II following Cataract Phacoemulsification surgery

Contact Info

Product

Resources

About