impact of vitamin D3 and B12 in patients with thyroid disorders in Kirkuk –Iraq

Abstract

Background: Thyroid disorders are common among Iraqis, and hypothyroidism has grown after the 2003 and 2014 events. Anemia and osteoporosis are caused by a lack of ferritin, iron, vitamins B12 and folic acid, as well as vitamin D3. Objectives: to determine thyroid status in people in Kirkuk province and to detect its relation to vitamin D3, B12 as well as its impact on main blood components. Setting: A preliminary cross-sectional study was conducted involving 105 patients attending Ibn-Nafees private medical lab. from both gender, suffering from thyroid dysfunction. their average ages were 38.12± 1.4 years. Methods: Thyroid hormones (T3), thyroid hormones (T4), and thyroid-stimulating hormone (TSH) were measured using the Mini-Vidas machine, and vitamin B12 was evaluated using an ELISA. The Sysmex XN-350 auto-analyzer was used to determine the complete blood count (CBC). Results: The total abnormality rate for thyroid function was 14.28 percent. This rate accounts for 9.52 percent of cases of hyperthyroidism and 4.76 percent of cases of hypothyroidism. Thyroid dysfunction is more prevalent in urban areas than in rural areas. Vitamin B12 insufficiency was often seen in hypothyroid individuals. There was a substantial correlation between hypothyroidism and patient gender.