Impact of volume and location of irradiated rectum wall on rectal blood loss after radiotherapy of prostate cancer

Koper, P.; Heemsbergen, Wilma D.; Hoogeman, M.; Jansen, Peter P.; Hart, Guus; Wijnmaalen, Arendjan; Os, Marjolein van; Boersma, Liesebeth J; Lebesque, Joos V.; Levendag, Peter C.

doi:10.1016/j.ijrobp.2003.08.008

Cited by 80 publications

(39 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the available literature, no correlation between rectal toxicity and exposure with doses of less than 40 Gy was observed. 29,30 We extended the analysis to compare the volume of the rectum that receives 100% of the prescription dose, according to studies of Carlson et al 23 No significant differences (p = 0.08) were found in the total volume of organ that receives the prescribed 76.32 Gy (on average, slightly less than 2 cc in both cases); however, these differences become statistically significant (p = 0.007) when we study the relative volume (in %) of the organ receiving 100% of the prescription dose, because the total volume appreciably oscillates (by a factor of 2) if we evaluate the entire rectum or the rectal wall. This result coincides well with Kusumoto et al 31 because they demonstrated that the absolute volume DVHs can be used for evaluating rectal toxicity because it depends less than that of relative DVHs on the contouring methods used for high dose levels.…”

Section: Discussionmentioning

confidence: 99%

Dosimetric impact in the dose–volume histograms of rectal and vesical wall contouring in prostate cancer IMRT treatments

Gómez

Andrés

Ruiz

2017

Reports of Practical Oncology & Radiotherapy

View full text Add to dashboard Cite

IMRT Dose-volume histogram Rectum wallBladder wall a b s t r a c t Aim:The main purpose of this study was to evaluate the differences in dose-volume histograms of IMRT treatments for prostate cancer based on the delineation of the main organs at risk (rectum and bladder) as solid organs or by contouring their wall.Background: Rectum and bladder have typically been delineated as solid organs, including

show abstract

Section: Discussionmentioning

confidence: 99%

Dosimetric impact in the dose–volume histograms of rectal and vesical wall contouring in prostate cancer IMRT treatments

Gómez

Andrés

Ruiz

2017

Reports of Practical Oncology & Radiotherapy

View full text Add to dashboard Cite

show abstract

“…The prostate, entire seminal vesicles and proximal seminal vesicles were delineated on each axial slice on the planning computer. The definition of the proximal seminal vesicles was taken from the literature [20]. Since the volume of the rectum increased to a great extent with a rectal balloon in place, compared to the volume of the rectum with no rectal balloon, the rectal wall volume was outlined.…”

Section: Methodsmentioning

confidence: 99%

“…Rectal toxicity following external beam irradiation of prostate cancer correlates with radiation dose, exposed rectal wall volume, in particular with the percentage of rectal volume included in the intermediate and high dose volume [1,16,20,27,28]. Efforts in optimizing external beam radiation to the prostate are aiming to increase the total dose applied to the prostate while minimizing the delivered dose to the organs at risk, e.g., the rectum [5,6,13,25].…”

Section: Introductionmentioning

confidence: 99%

The Impact of Varying Volumes in Rectal Balloons on Rectal Dose Sparing in Conformal Radiation Therapy of Prostate Cancer

Hille

Schmidberger²,

Töws³

et al. 2005

Strahlenther Onkol

View full text Add to dashboard Cite

The use of a rectal balloon filled with 60 ml air led to a significantly decreased proportion of the irradiated rectal wall for all CTVs. This volume filled in rectal balloons is therefore recommended for use. In case of irradiation of the prostate without the seminal vesicles, the use of a rectal balloon should be considered carefully concerning the patients' imaginable discomfort using a rectal balloon and a questionable advantage concerning the estimated risk for chronic toxicity.

show abstract

“…ScHARR brings together a wide range of medical-and health-related disciplines including public health, general practice, mental health, epidemiology, health economics, management sciences, medical statistics, operational research and information science. 67.5 (21.9) 0.13, mean (SD) dose to posterior rectum (Gy) 35.3 (8.6), mean (SD) dose to anterior rectum (Gy) 74.8 (1.4). Planning process combined two phases, a boost to the prostate and a pelvic treatment The initial boost delivers 16 Gy over eight fractions and it is followed by a 6 MV X-ray eight-field coplanar inverse planning IMRT technique delivering an additional 60 Gy over 30 fractions to the prostate (76 Gy total) and 54 Gy over 30 fractions to the SVs and PNs.…”

Section: About Scharrmentioning

confidence: 99%

“…65 However, increased dose can increase toxicity, as has been shown in RCTs of dose escalation. 66,67 Doses upward of 78-80 Gy are difficult to achieve when using 3DCRT, due to the unacceptable risk of side effects. 68 The benefit of IMRT is largely related to the avoidance of side effects of radiation.…”

mentioning

confidence: 99%

Intensity-modulated radiotherapy for the treatment of prostate cancer: a systematic review and economic evaluation

Hummel

Simpson²,

Hemingway³

et al. 2010

Health Technol Assess

View full text Add to dashboard Cite

How to obtain copies of this and other HTA programme reports An electronic version of this title, in Adobe Acrobat format, is available for downloading free of charge for personal use from the HTA website (www.hta.ac.uk). A fully searchable DVD is also available (see below).Printed copies of HTA journal series issues cost £20 each (post and packing free in the UK) to both public and private sector purchasers from our despatch agents.Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per issue and for the rest of the world £3 per issue. How to order:-fax (with credit card details) -post (with credit card details or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you to either print out your order or download a blank order form. Contact details are as follows:Synergie UK (HTA Department) Digital House, The Loddon Centre Wade Road Basingstoke Hants RG24 8QW Email: orders@hta.ac.uk Tel: 0845 812 4000 -ask for 'HTA Payment Services' (out-of-hours answer-phone service) Fax: 0845 812 4001 -put 'HTA Order' on the fax header Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to University of Southampton and drawn on a bank with a UK address. Paying by credit cardYou can order using your credit card by phone, fax or post. SubscriptionsNHS libraries can subscribe free of charge. Public libraries can subscribe at a reduced cost of £100 for each volume (normally comprising 40-50 titles). The commercial subscription rate is £400 per volume (addresses within the UK) and £600 per volume (addresses outside the UK). Please see our website for details. Subscriptions can be purchased only for the current or forthcoming volume. How do I get a copy of HTA on DVD?Please use the form on the HTA website (www.hta.ac.uk/htacd/index.shtml). HTA on DVD is currently free of charge worldwide.The website also provides information about the HTA programme and lists the membership of the various committees. HTA NIHR Health Technology Assessment programmeT he Health Technology Assessment (HTA) programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care. The research findings from the HTA programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a key component of the 'National Knowledge Service'. The HTA programme is needs led in that it fills gaps in the evidence needed by the NHS. There are three routes to the start of project...

show abstract

Impact of volume and location of irradiated rectum wall on rectal blood loss after radiotherapy of prostate cancer

Cited by 80 publications

References 28 publications

Dosimetric impact in the dose–volume histograms of rectal and vesical wall contouring in prostate cancer IMRT treatments

Dosimetric impact in the dose–volume histograms of rectal and vesical wall contouring in prostate cancer IMRT treatments

The Impact of Varying Volumes in Rectal Balloons on Rectal Dose Sparing in Conformal Radiation Therapy of Prostate Cancer

Intensity-modulated radiotherapy for the treatment of prostate cancer: a systematic review and economic evaluation

Contact Info

Product

Resources

About