Impact on mortality and incidence of end-stage renal disease of education and treatment at a diabetes center among patients with type 1 diabetes

Changes in the prognosis of Japanese patients who developed type 1 diabetes before the age of 30 years

“…Deckert et al indicated in 1978 that the prognosis of T1DM cases receiving treatment at specialized care from Steno Diabetes Center was favorable, suggesting the importance of guidance for care by specialists [12]. We reported in the Japanese DERI cohort that the mortality and incidence of end-stage renal disease (ESRD) in patients who had visited our center were lower than in those who had not [5], and the crude mortality in the survey was 1.95 per 1000 person-years. The findings observed in the present study likely extended the Deckert's findings.…”

“…The subjects with T1DM who visited the Department of Pediatrics after 1988 were not included in the records of the Diabetes Center and were not included in this study. The diagnosis of T1DM was performed as previously reported [5,6] and was in accordance with the Japan Diabetes Society (JDS) criteria [7]. In brief, Type 1 diabetes was defined as being prone to ketosis with acute onset and requiring insulin therapy within 1 year of diagnosis.…”

“…A diabetes center was established in 1975 at Tokyo Women's Medical University (TWMU) as the first of its kind in Japan. It has the largest number of patients with T1DM in Japan as previously reported [6], and 13.4% of the subjects in the Japanese DERI cohort [5] was derived from this center.…”

“…Introduction mortality rate and SMR in Japanese patients with T1DM among hospitals in which the mortality per 1000 person-years varied from 1.90 to 6.05 [4,5], and the prognosis of T1DM diagnosed after 1980 is uncertain. A diabetes center was established in 1975 at Tokyo Women's Medical University (TWMU) as the first of its kind in Japan.…”

Incidence and Development of Diabetic Microangiopathy of Fulminant Type 1 Diabetes -Comparison with Non-fulminant Type 1 Diabetes-

“…We have reported that the mortality and incidence of endstage renal disease in patients with type 1 diabetes in our diabetes center were significantly lower than those in general hospitals (5 …”