Impact on quality of life of botulinum toxin treatments for essential blepharospasm

MacAndie, Kerr; Kemp, Ewan

doi:10.1080/01676830490506041

Cited by 31 publications

(18 citation statements)

References 10 publications

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“…Although these all take slightly different approaches, the results for external DCR range from þ 18.5 9 to þ 23.2, 10 and for endonasal DCR from þ 16.8 10 to þ 52.0. 11 Elsewhere in the literature, satisfaction with botulinum toxin is reported as þ 29.2 for blepharospasm, 14 and þ 38.0 for spasmodic dysphonia, 16 and with otorhinolaryngological surgery at þ 20.0 for rhinoplasty, 17 þ 11.3 for septoplasty, 18 and þ 23.0 for functional endoscopic sinus surgery. 19 …”

Section: Introductionmentioning

confidence: 99%

“…However, a major strength of the GBI is its ability to compare a range of different treatments for a variety of conditions, and across diverse demographic and cultural groups. It also benefits from being post-interventional quick and easy to administer by telephone or post, focused on change (rather than taking preoperative and postoperative measures and subtracting one from the other), and its use has been validated for oculoplastic procedures (DCR 9-13 and botulinum toxin for blepharospasm 14 ).…”

Section: Introductionmentioning

confidence: 99%

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Patient-reported benefit from oculoplastic surgery

Smith

Jyothi

Mahroo

et al. 2012

Eye

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Purpose It is vital that surgeons undertaking oculoplastic procedures are able to show that the surgery they perform is of benefit to their patients. Not only is this fundamental to patient-centred medicine but it is also important in demonstrating cost effectiveness. There are several ways in which benefit can be measured, including clinical scales, functional ability scales, and global quality-of-life scales. The Glasgow benefit inventory (GBI) is an example of a patient-reported, questionnaire-based, postinterventional quality-of-life scale that can be used to compare a range of different treatments for a variety of conditions. Methods A cross-sectional study was undertaken using the GBI to score patient benefit from four commonly performed oculoplastic procedures. It was completed for 66 entropion repairs, 50 ptosis repairs, 41 ectropion repairs, and 41 external dacryocystorhinostomies (DCR). The GBI generates a scale from À 100 (maximal detriment) through zero (no change) to þ 100 (maximal benefit). Results The total GBI scores of patients undergoing surgery for entropion, ptosis, ectropion, and external DCR were: þ 25. Po0.001), Po0.001), Po0.001), and þ 32.25 (95% CI 21.47-43.03, Po0.001), respectively, demonstrating a statistically significant benefit from all procedures. Conclusion Patients derived significant quality-of-life benefits from the four most commonly performed oculoplastic procedures.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Patient-reported benefit from oculoplastic surgery

Smith

Jyothi

Mahroo

et al. 2012

Eye

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“…One study identifi ed up to 40 % of BEB patients as suffering from depression (Müller et al 2002b ;Wenzel et al 2000 ). Fortunately, those undergoing treatment with botulinum toxin have shown improvement in quality of life (MacAndie and Kemp 2004 ). In addition to those treatments discussed above, patients may enjoy improvement in symptoms and quality of life through the use of sunglasses, better dry eye control with punctual plugs, biofeedback exercises, acupuncture, or relaxation.…”

Section: Prognosismentioning

confidence: 98%

Management of Benign Essential Blepharospasm

Woodward¹,

Rao

2014

Pearls and Pitfalls in Cosmetic Oculoplastic Surgery

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“…It has been used in over 100 studies of different otorhinolaryngological interventions, and also more recently in a number of studies of oculoplastic procedures. [5][6][7][8][9] The instrument has not been used in cataract surgery, but such data would be useful to allow comparison with other procedures. This pilot study aimed to assess whether the GBI would be sensitive enough to pick up changes in quality of life as early as a few weeks following routine cataract surgery.…”

Section: Introductionmentioning

confidence: 99%

Changes in quality of life shortly after routine cataract surgery

Heemraz

Lee

Hysi

et al. 2016

Canadian Journal of Ophthalmology

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ObjectiveA pilot study to explore use of a generic patient-reported outcome measure to assess patient-perceived improvements in quality of life within 2-4 weeks of routine cataract surgery, and to explore differences after first or second eye surgery. Secondary analysis explored effects of gender and ethnicity. DesignProspective observational study. ParticipantsConsecutive patients attending a weekly nurse-led postoperative clinic. MethodsThe Glasgow Benefit Inventory (GBI), a validated, post-interventional questionnaire (not specific to one particular medical or surgical intervention), was administered. Mean scores were calculated. Scores were compared when patients were grouped by first or second eye, and by gender or ethnicity (unpaired t test). Scores potentially range from +100 (maximum benefit) to -100 (maximum detriment). 3 ResultsThe GBI was administered 113 times to 109 patients (4 patients were seen following both first and second eye surgery). Mean overall score was +22.8 (median +19.4; SD 19.7; 95% CI +19.2 to +26.4). Mean (SD) sub-scores were +30.5 (25.3), +17.8 (26.7) and -3.1 (19.9) for general, social support and physical health sub-domains respectively. Total benefit scores were not significantly different for first or second eye surgery, or across gender (p>0.3). Scores for patients of African (including African Caribbean) ethnicity were significantly higher than those obtained from European patients (p=0.002).

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Impact on quality of life of botulinum toxin treatments for essential blepharospasm

Abstract: This study demonstrates significant quality of life benefit from Botulinum toxin therapy for essential blepharospasm, and justifies continued treatment.

Cited by 31 publications

References 10 publications

Patient-reported benefit from oculoplastic surgery

Patient-reported benefit from oculoplastic surgery

Management of Benign Essential Blepharospasm

Changes in quality of life shortly after routine cataract surgery

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