Impact on Quality of Life After Pancreatoduodenectomy: A Prospective Study Comparing Preoperative and Postoperative Scores

Chan, Carlos; Franssen, Bernardo; Domínguez, Ismael; Val, Alejandro Ramírez-Del; Uscanga, Luis; Campuzano, M

doi:10.1007/s11605-012-1898-2

Cited by 31 publications

(41 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, social functioning and emotional role restriction improved after surgery following a short decline. This trend was reported previously. A positive effect for mental health over time was observed here.…”

Section: Discussionsupporting

confidence: 92%

“…Patients completed this questionnaire at home after visiting the surgeon and sent it back by mail, or completed it in the waiting room. Follow‐up questionnaires were scheduled for completion during routine visits to the outpatient department at 1, 3, 6 and 12 months after surgery, until loss to follow‐up or death. Patients who remained in hospital were considered unable to complete questionnaires.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Health-related quality of life after pancreatic resection for malignancy

Heerkens

Tseng

Lips

et al. 2016

Journal of British Surgery

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Methodsmentioning

confidence: 99%

Health-related quality of life after pancreatic resection for malignancy

Heerkens

Tseng

Lips

et al. 2016

Journal of British Surgery

View full text Add to dashboard Cite

show abstract

“…Analysis of the questionnaires did not reveal any differences in quality of life between the groups. A decline in HRQoL 1 month after PD is expected and has been described previously 34 . There are no studies evaluating quality of life after implementation of FT PD, but a comparison of FT versus traditional management of patients undergoing colorectal surgery showed no difference in EORTC QLQ-C30 scores 35 .…”

Section: Discussionsupporting

confidence: 66%

Impact of a fast-track surgery programme for pancreaticoduodenectomy

Williamsson

Karlsson

Sturesson

et al. 2015

British Journal of Surgery

View full text Add to dashboard Cite

Background: Fast-track (FT) programmes are multimodal, evidence-based approaches to optimize patient outcome after surgery. The aim of this study was to evaluate the safety, clinical outcome and patients' experience of a FT programme after pancreaticoduodenectomy (PD) in a high-volume institution in Sweden.Methods: Consecutive patients undergoing PD were studied before and after implementation of the FT programme. FT changes included earlier mobilization, standardized removal of the nasogastric tube and drain, and earlier start of oral intake. Patient experience was evaluated with European Organization for Research and Treatment of Cancer QLQ-C30 and QLQ-PAN26 questionnaires 2 weeks before and 4 weeks after surgery.Results: Between 2011 and 2014, 100 consecutive patients undergoing PD were studied, of whom 50 received standard care (controls), followed by 50 patients treated after implementation of the FT programme. The nasogastric tube was removed significantly earlier in the FT group, and these patients were able fully to tolerate fluids and solid food sooner after PD. Delayed gastric emptying was significantly reduced in the FT group (26 versus 48 per cent; P = 0⋅030). Overall morbidity remained unchanged and there were no deaths in either group. Postoperative length of hospital stay was reduced from 14 to 10 days and hospital costs were decreased significantly. Health-related quality-of-life questionnaires showed similar patterns of change, with no significant difference between groups before or after surgery. Conclusion:The FT programme after PD was safe. Delayed gastric emptying, hospital stay and hospital costs were all reduced significantly. Although patients were discharged 4 days earlier in the FT group, this did not influence health-related quality of life compared with standard care.

show abstract

“…It has been shown that operated patients have a higher quality of life 6 months postoperatively than before surgery [56].…”

Section: Operability Assessmentmentioning

confidence: 99%

Pancreatic Cancer: Yesterday, Today and Tomorrow

et al. 2016

View full text Add to dashboard Cite

Pancreatic cancer is one of our most lethal malignancies. Despite substantial improvements in the survival rates for other major cancer forms, pancreatic cancer survival rates have remained relatively unchanged since the 1960s. Pancreatic cancer is usually detected at an advanced stage and most treatment regimens are ineffective, contributing to the poor overall prognosis. Herein, we review the current understanding of pancreatic cancer, focusing on central aspects of disease management from radiology, surgery and pathology to oncology. Historical remarks & present stateThe first known description of pancreatic cancer is attributed to Giovanni Battista Morgagni in his 1761 publication 'de Sedibus Et Causis Morborum Per Anatomen Indagatis Libri Quinque' [1]. However, the lack of a microscopic evaluation makes the true diagnosis of ductal adenocarcinoma uncertain. The next important advancement in our understanding of pancreatic cancer did not come until 1858, when Jacob Mendez Da Costa revisited Morgagni's original work and also described the first microscopic diagnosis of adenocarcinoma, manifesting pancreatic cancer as a true disease entity [2].The history of pancreatic surgery is fairly recent and involves a combination of brave surgical pioneers, the development of surgical anesthesia and modern aseptic techniques. Some landmarks in the history of pancreatic surgery deserve to be mentioned. The first reported attempt at a pancreaticoduodenectomy was performed in 1898 by the Italian surgeon Alessandro Codivilla for a tumor involving the head of the pancreas [3]; however, the patient did not survive the postoperative period. In the same year, William Stewart Halsted from Johns Hopkins Hospital performed the first successful resection for ampullary cancer by excising portions of the duodenum and the pancreas [4]. The first successful pancreaticoduodenectomy is credited to the German surgeon Walther Carl Eduard Kausch, as part of a two-stage procedure [5]. In 1914, Georg Hirschel performed the first successful pancreaticoduodenectomy in one stage [6] and then in 1935, Allen Oldfather Whipple presented the results of a two-stage procedure involving the resection of the head of the pancreas and duodenum for ampullary carcinoma at the annual meeting of the American Surgical Association, which renewed interest in pancreatic surgery [7]. During his career, Whipple performed 37 pancreaticoduodenectomies, with the procedure evolving into a one-stage technique [8,9], and 1964-1968 1969-1973 1974-1978 1979-1983 1984-1988 1989-1993 1994-1998 1999-2003 2004-2008 2009-2013 Period of diagnosis Whipple is generally credited with popularizing the operation that still bears his name. In 1937, Alexander Brunschwig performed the first successful pancreaticoduodenectomy for pancreatic adenocarcinoma [10]. Today, with the concentration of experience in high-volume hospitals, pancreatic surgery has become a safe procedure associated with an operative mortality below 3% [11][12][13]. While major advances have been made ...

show abstract

Impact on Quality of Life After Pancreatoduodenectomy: A Prospective Study Comparing Preoperative and Postoperative Scores

Abstract: PD has a favorable impact in quality of life as demonstrated by the improvement of most parameters assessed in the postoperative period.

Cited by 31 publications

References 12 publications

Health-related quality of life after pancreatic resection for malignancy

Health-related quality of life after pancreatic resection for malignancy

Impact of a fast-track surgery programme for pancreaticoduodenectomy

Pancreatic Cancer: Yesterday, Today and Tomorrow

Contact Info

Product

Resources

About