Impact on the survival of neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and monocyte-lymphocyte ratio on prognosis in children with Hodgkin lymphoma

Ertan, Kubra; Dogru, Aysenur; Kara, Buket; Köksal, Yavuz

doi:10.15537/smj.2022.43.5.20210916

Cited by 3 publications

(2 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recently, there are studies on the use of some biomarkers such as NLR, PLR, MLR in lymphomas. [5,13,14] Biological markers such as NLR, PLR, and MLR were found to be higher in children with lymphoma compared to children with reactive lymphadenopathy. In multivariate odd ratios of variables for predicting malignancy in all children, the statistical significance of age, extension, hemoglobin and MLR were determined.…”

Section: Multivariate Analysismentioning

confidence: 99%

Hodgkin dışı lenfomalı çocukların klinik özelliklerinin, tedavi yaklaşımlarının ve tedavi sonuçlarının değerlendirilmesi

Kara

Uğraş

Ertan

et al. 2022

Journal of Contemporary Medicine

Self Cite

View full text Add to dashboard Cite

Aim: To evaluate the demographic and clinical characteristics, treatment approaches and outcomes of our pediatric patients with non-Hodgkin lymphoma diagnosed and treated in our center. Material and Methods: Between 2006 and 2002, the oncologic charts of the patients diagnosed and followed up as non-Hodgkin lymphoma were reviewed retrospectively. Results: Eighty children with non-Hodgkin lymphoma were included in this study. There were 55 boys (68.8%) and 25 girls (31.2%). The patients’ ages ranged from 2 to 18 years (median: 11.1 years). Nine patients (11.3%) had primary immunodeficiency. Sixty-three of the patients were stage III (78.7%). The majority pathologic subtype was Burkitt lymphoma (n: 31, 38.8%). The overall survival and event-free survival rates were 71.7% and 71.5%, respectively. The patients’ overall survival rates without and with primary immunodeficiency was 81.1% and 11.1%, respectively. There was a significant difference between these two groups. Cox regression analysis showed that advanced stage and concomitant primary immunodeficiency have been risk factors for prognosis. Conclusion: Intensive treatment approaches have increased overall survival rates in children with non-Hodgkin lymphoma. However, this success rate cannot be achieved in non-Hodgkin lymphoma children with primary immunodeficiency.

show abstract

Section: Multivariate Analysismentioning

confidence: 99%

Hodgkin dışı lenfomalı çocukların klinik özelliklerinin, tedavi yaklaşımlarının ve tedavi sonuçlarının değerlendirilmesi

Kara

Uğraş

Ertan

et al. 2022

Journal of Contemporary Medicine

Self Cite

View full text Add to dashboard Cite

show abstract

“…These white blood cell populations are involved in the patho-mechanisms of inflammation and stress disorders at the same time [ 8 , 9 ]. In humans, NLR, MLR, and platelet-to-lymphocyte ratio (PLR) values were studied as inflammatory markers in various conditions for diagnostic and prognostic purposes [ 2 , 8 , 10 , 11 , 12 , 13 , 14 ]. High values of NLR and MLR were considered accurate additional markers in the diagnosis of acute coronary syndrome [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

A Retrospective Comparative Evaluation of Selected Blood Cell Ratios, Acute Phase Proteins, and Leukocyte Changes Suggestive of Inflammation in Cats

Donato

Pennisi

Persichetti

et al. 2023

Animals

View full text Add to dashboard Cite

Neutrophil-to-lymphocyte (NLR), monocyte-to-lymphocyte (MLR), and platelet-to-lymphocyte (PLR) ratios have been proposed as diagnostic and prognostic markers for neoplastic and inflammatory diseases in dogs and cats. The aim of this retrospective preliminary study was to evaluate the relationship between these ratios and markers of inflammation routinely measured in cats. A total of 275 cats were enrolled. Complete blood count, serum amyloid A (SAA), albumin, globulin, and albumin-to-globulin ratio (AGR) data were analyzed, as well as the presence of leukocyte alterations considered suggestive of inflammation (LAI: neutrophils left shift, toxic neutrophils, and reactive lymphocytes) evaluated in blood smears. The NLR and MLR correlated positively with SAA and globulins and negatively with albumin and AGR. Higher NLR and MLR were found in cats with increased SAA and globulins and decreased albumin and AGR. The PLR correlated negatively with albumin and AGR. A higher PLR was found in cats with hypoalbuminemia. Cats with LAI had higher NLR, MLR, and PLR. In cats with no changes in parameters indicative of inflammation, 11.25, 0.42, and 528.3 were identified as upper limits for NLR, MLR, and PLR, respectively. In conclusion, the NLR, MLR, and PLR act as good inflammatory markers easily evaluated by routine hematology.

show abstract

Development and Validation Of A Novel Nomogram Prognostic Model for Predicting the Overall Survival of Lymphoma: A Cohort Study in China

Xu,

Li,

et al. 2023

Preprint

View full text Add to dashboard Cite

Impact on the survival of neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and monocyte-lymphocyte ratio on prognosis in children with Hodgkin lymphoma

Cited by 3 publications

References 21 publications

Hodgkin dışı lenfomalı çocukların klinik özelliklerinin, tedavi yaklaşımlarının ve tedavi sonuçlarının değerlendirilmesi

Hodgkin dışı lenfomalı çocukların klinik özelliklerinin, tedavi yaklaşımlarının ve tedavi sonuçlarının değerlendirilmesi

A Retrospective Comparative Evaluation of Selected Blood Cell Ratios, Acute Phase Proteins, and Leukocyte Changes Suggestive of Inflammation in Cats

Development and Validation Of A Novel Nomogram Prognostic Model for Predicting the Overall Survival of Lymphoma: A Cohort Study in China

Contact Info

Product

Resources

About