Impaction bone grafting using freeze-dried allograft in revision hip arthroplasty

Roeck, Nicholas J. de; Drabu, K J

doi:10.1054/arth.2001.20250

Cited by 54 publications

(31 citation statements)

References 28 publications

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“…Many authors have reported an improvement in implant stability in femoral and acetabular impactions using a morselized graft that had been simply washed with saline (Kärrholm et al 1999, Ullmark 2000, Höstner et al 2001. In clinical studies, good results have also been reported using defatted freeze-dried bone (Mazhar et al 2001, de Roeck and Drabu 2001, Thien et al 2001. Replacing bone marrow by saline improves liquid flow, particularly after high speed stress (Carter and Hayes Defatted grafts compacted much faster than the fresh-frozen bone, as shown by the greater reduction in height from 1 to 50 impactions.…”

Section: Discussionmentioning

confidence: 99%

Freeze-dried irradiated bone brittleness improves compactness in an impaction bone grafting model

Libouton

Naets

Godts

et al. 2004

Acta Orthopaedica Scandinavica

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Background Defatted bone chips with or without freeze-drying and irradiation have mechanical advantages as compared to fresh-frozen controls in in vitro models of impaction. These improved results have been ascribed to replacement of viscous bone marrow by saline and embrittlement of the freeze-dried bone by irradiation.Material and methods To determine which of these hypotheses is correct, we compared the development of stiffness and compactness of morselized bone graft that had been: 1) fat-reduced with saline, and 2) fresh-frozen, solvent-detergent defatted, 3) freeze-dried irradiated and 4) not irradiated. We used 12 osteoarthrotic femoral heads to prepare these four batches of morselized bone, and impacted 18 samples from each batch in a cylinder. The frozen bone grafts were tested after thawing at room temperature for 2 hours and the freeze-dried grafts were tested after 30 minutes of rehydration. We monitored the development of compactness and stiffness of the material during impaction.Results The stiffness of the freeze-dried irradiated bone was greater than that of the other three series after 10, 50 and 150 impactions. The freeze-dried bone chips that were not irradiated and the chips defatted with saline alone were less stiff than the fresh-frozen control after 150 impactions.Interpretation The brittleness of freeze-dried irradiated bone, caused by loss of the capacity to absorb energy in a plastic way, increases the compactness and stiffness of the morselized grafts. Washing bone with saline alone or treating bone with solvent-detergent but no irradiation had no similar mechanical advantage and the bone did not impact better than fresh-frozen undefatted bone in our model.

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Section: Discussionmentioning

confidence: 99%

Freeze-dried irradiated bone brittleness improves compactness in an impaction bone grafting model

Libouton

Naets

Godts

et al. 2004

Acta Orthopaedica Scandinavica

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“…However, in HTAR surgeries, we found few indexed articles reporting the use of human lyophilized grafts, and even fewer papers addressing bovine bone grafting. 10,11 Such resistance showed by hip surgeons to use lyophilized grafts may be partially associated to the diversity of grafts commercially available, with distinct purposes and indications. As a result, dif- ferent mechanical and biological responses are seen, may times causing a certain fear, due to unawareness, at the moment of choosing and using this kind of graft.…”

Section: Discussionmentioning

confidence: 99%

Osteointegração de enxertos liofilizados impactados

2009

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Acta Ortop Bras. 2009; 17(2):24-8 analysis was based on Merle, d'Aubigné and Postel's scores; while the radiographic analysis was based on an established score for radiographic bone incorporation. Results: No clinical or radiographic differences were found between the groups, and both groups showed an overall osteointegration rate of 85% both in the acetabular and in the femoral component. Conclusions: Impacted lyophilized human and bovine bone grafts produced by following to the proposed protocol did not cause damage to the patients. Results obtained with both bovine and human grafts were similar. Keywords ABSTRACTObjective: The purpose of the study was to provide a clinical and X-ray based evaluation of the results and osteointegration ability of lyophilized human and bovine bone grafts. Methods: This is a non-concurrent cohort trial of 63 patients (66 hips) submitted to revision total hip arthroplasty (RTHA) using impacted freezedried human and bovine cancellous bone grafts. The study was carried out in the

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“…Morselised fresh-frozen allograft has been considered as the standard graft [5,19], but recent series using irradiated allograft show good results in a medium-and long-term follow-up [2,6,10].…”

Section: Discussionmentioning

confidence: 99%

Acetabular revision with freeze-dried irradiated and chemically treated allograft: a minimum 5-year follow-up of 17 cases

Vargas

Caton²

2007

International Orthopaedics (SICO

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Impaction bone grafting using freeze-dried allograft in revision hip arthroplasty

Cited by 54 publications

References 28 publications

Freeze-dried irradiated bone brittleness improves compactness in an impaction bone grafting model

Freeze-dried irradiated bone brittleness improves compactness in an impaction bone grafting model

Osteointegração de enxertos liofilizados impactados

Acetabular revision with freeze-dried irradiated and chemically treated allograft: a minimum 5-year follow-up of 17 cases

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