Abstract. Over the period 1990-2010, maritime Southeast Asia experienced large-scale land cover changes, including expansion of high-isoprene-emitting oil palm plantations and contraction of low-isoprene-emitting natural forests. The ModelE2-Yale Interactive Terrestrial Biosphere global chemistry-climate model is used to quantify the atmospheric composition changes and, for the first time, the associated radiative forcing induced by the land-cover-change-driven 10 biogenic volatile organic compound (BVOC) emission changes (+6.5 TgC y -1 isoprene, -0.5 TgC y -1 monoterpenes).Regionally, surface-level ozone concentrations largely decreased (-3.8 to +0.8 ppbv). The tropical land cover changes occurred in a region of strong convective transport, providing a mechanism for the BVOC perturbations to affect the composition of the upper troposphere. Enhanced concentrations of isoprene and its degradation products are simulated in the upper troposphere, and, on a global-mean basis, land cover change had a stronger impact on ozone in the upper troposphere 15 (+0.6 ppbv) than in the lower troposphere (< 0.1 ppbv increase). The positive climate forcing from ozone changes (+9.2 mW m -2 ) was partially offset by a negative forcing (-0.8 mW m -2 ) associated with a regional enhancement in secondary organic aerosol concentrations. The global-mean ozone forcing per unit of regional oil palm expansion is +1 mW m -2 Mha -1 . In light of expected continued expansion of oil palm plantations, regional land cover changes may play an increasingly important role in driving future global ozone radiative forcing. 20